THE

STRUCTURE
OF
THE FOUR
 OSTEOGENIC CELLS

Osteogenic cells are stem cells that are

located in the surface lining of bones
marrow.
Osteogenic cell are undiffentiated, they are
undefined and eventuallybecome other
Kinds of cells in other words stem cells.
 OSTEOBLASTS CELLS

A cell that make bone. It does so by

producing a that then becomes
mineralized. Bone mass is maintained
by a balanced between the activity of
osteoblasts that form bone and other
cells called osteoclasts that break it
down.
 OSTEOCLASTS
CELLS
An osteoclasts from the greek word (oston),
meaning “bone” and (clatos), meaning “broken”
is a type of bone cell that breaks down bone tissue.
This function is critical in the maintenance, repair
and remodeling of bones of vertebral skeleton.
 OSTEOCYTES CELLS
Osteocytes, a cell that lies within the
substance of fully formed bone, It occupies a
small chamber called lacuna: which is
contained in the calcified matrix of bone .
Osteocytes derive from osteoblast, or
bone – forming cells, and are products they
secreted
DIFFERENCE
OF THE FOUR
BONE CELLS
 OSTEOGENIC CELLS

 Huge cells from fused monocytes

 Function in home desorption at surfaces such s edosteum
 Digest bone
 Large multi-nucleard
 Exhibit ruffled border and clear zone
 Exhibits polarity with nuclei away from bone surface
 OSTEOBLAST CELLS

Form matrix and collagen fibers but can’t

divide
Differentiates to become osteocytes
Positioned above osteoid matrix
Regulates mineralization type 1 collagen
 OSTEOCLAST CELLS

Huge cells from fussed monocytes

Function in bone resorption at surfaces such as
endosteum
Digest bone
Large multi-nucleared
Exhibits ruffled border and clear zone
exhibits polarity with nuclei away from bone surface
High density of golgi stacks, mitochondria and
lysozomal vesicles
 OSTEOCYTES

 Mature cells that no longer secrete matrix

 Born from osteoblasts
 Maintain bone matrix
 Occupies lucunae
 Extends filipodia through canaliculi
 Forms gap junction with neighboring cells