Poster No.

PP-000

Blood Pressure Outcomes in Elderly Hypertensive

Patients Treated with Amlodipine as Monotherapy: A
Randomized Trial
Pratiwi Rulinny, Pasaman Barat Hospital

Introduction:
In Indonesia, the number of people with hypertension has increased by more than 20 million in
just 5 years. Elderly patients (those 60 years of age and older) with a high comorbid rate make up
more than a third of those diagnosed with hypertension. Hypertension has become one of the
problems of non-communicable diseases that must be treated seriously. Hypertension
management requires the use of antihypertensive medications and modification of lifestyle
factors. Amlodipine is one of the most popular options for treating hypertension in older patients
in Indonesia. Amlodipine is performed on monotherapy patients in first-rate facilities and
evaluated by a general practitioner The goal of this study is to determine whether amlodipine,
used as a monotherapy in primary healthcare, is beneficial in treating older adults with newly
diagnosed hypertension.

Results:
Materials: However, after six months, more than half
A single randomized clinical study was of the patients still did not achieve normal
conducted at AA Primary Health Care Services systolic blood pressure despite taking
between November 2021 and May 2022 with amlodipine (mean SBP 144,389 ± 1,4
70 patients who had recently been diagnosed mmHg). In diastolic blood pressure,
with hypertension, were 60 years old or older, significantly decreases and reaches normal
and had never received treatment for the pressure (mean DBP 80,36 ± 4,5 mmHg).
condition.
The subjects were given 5 mg of
amlodipine once daily for six months.
Throughout the experiment, monthly
blood pressure measurements were
taken. The study employs repeatedly
measured ANOVA, and the p-value is
adjusted using the Bonferroni
method

Results : figure 1 systolic rate in six months

A total of 70 people were randomly assigned
to treatment in this study, with 67 of them
eligible for analysis. The average age in this
study was 65,5 years, with women
outnumbering men (61.1%).

Amlodipine reduced systolic blood pressure

significantly by 31,9 ± 1.6 mmHg (p<0.001)in
systolic blood pressure (SBP) in figure 1 and
13,84 9 ± 1.1 mmHg (p<0.001) in diastolic
blood pressure (DBP) in figure 2. Most
patients (87.9%) displayed BP control with figure 2 diastolic rate in six months
amlodipine 5 mg at 4 months.

Conclusion:
Amlodipine can lower systolic and diastolic blood pressure in elderly patients newly diagnosed
with hypertension. Amlodipine, on the other hand, cannot restore normal
systolic blood pressure