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Secrets of Physio
OBJECTIVES
1. FUNCTIONAL ANATOMY OF THE EYE
2. EYE OPTICS AND IMAGE FORMATION
3. PHYSIOLOGY OF VISION
4. VISUAL PATHWAY
5. REFLEXES: ACCOMODATION AND PUPILARY REFLEXES
6. APPLIED ASPECTS AND CLINICALLY RELEVANT
CONDITIONS
PUPILARY REFLEXES
1. LIGHT REFLEXES
2. CILIOSPINAL REFLEXES
3. ACCOMODATION REFLEX
LIGHT REFLEX
• This is a reflex in which the pupil constricts when light is flashed into
the eyes.
• It is of two types:
• Direct light reflex: there is constriction of pupil in an eye when light
is thrown into that eye.
• Indirect light reflex: involves constriction of pupil in both eyes when
light is thrown into one eye. It is also called consensual light reflex.
PATHWAY FOR THE LIGHT REFLEX
• Fibers of light reflex pathway and the fibers of visual pathway
are the same up to optic tract. Beyond that these two sets of
fibers are separated.
• When light falls on the eye, the visual receptors are stimulated.
• Afferent (Sensory) impulses from the receptors pass through
optic nerve, optic chiasma and optic tract.
• At the midbrain level, few fibers get separated from optic tract and
synapse on the neurons of pretectal nucleus which lies close to the
superior colliculus.
• Pretectal nucleus of midbrain forms the center for light reflexes.
• Both pretectal nuclei are connected by the posterior commissure.
• Efferent (motor) impulses from the pretectal nucleus are carried by short
fibers to Edinger-Westphal nucleus (parasympathetic nucleus) of
oculomotor nerve (third cranial nerve).
• From Edinger-Westphal nucleus (parasympathetic) of oculomotor reach
the ciliary ganglion.
• Post-ganglionic fibers arising from ciliary ganglion pass through short
ciliary nerves and reach the eyeball. These fibers cause contraction of
constrictor pupillae muscle of iris.
• Contraction of the constrictor pupilae is mediated by M3
receptors which are Gq coupled receptors (Phopholipase C,
DAG and IP3)
• Reason for consensual light reflex is that, some fibers from pretectal
nucleus of one side cross to the opposite side and end on opposite
Westphal nucleus.
• In neurosyphilis, light reflexes are lost due to a lesion in the pretectal
nucleus.
• Pupilary dilation is caused by contraction of the dilator pupillae which is
supplied by the sympathetic nerve.
CILIOSPINAL REFLEXES
• Ciliospinal reflex is the dilatation of pupil in eyes caused by painful
stimulation of skin over the neck.
• It is due to the contraction of dilator pupillae muscles.
• Sensory impulses pass through cutaneous afferent nerve.
• The center is in first thoracic spinal segment.
• Efferent pass through sympathetic fibers and reach dilator pupillae.
ACCOMMODATION
• This is the adjustment of eye to see either near or distant objects clearly.
• It is a process by which light rays from near objects or distant objects are brought to a focus
on sensitive parts of the retina.
• It is achieved by various adjustments made in the eyeball.
NEAR VISION ACCOMMODATION
• This is achieved by:
• Convergence of eyeballs by contraction medial recti.
• Constriction of the pupil by contraction of constrictor pupillae of iris.
• Increase in the anterior curvature of the lens due to contraction of the
ciliary muscle.
Secrets of Physio