Optimal Immune System Support

Product Training
 THE HUMAN IMMUNE SYSTEM
...…is a complicated network of cells, antibodies and
proteins that serves following three main functions:

1. Removes waste and harmful material, to

ensure the normal function of the body.

2. Defends against pathogens - bacteria, fungi

and virus.

3. Kills and removes dead and altered cells.

 THE HUMAN IMMUNE SYSTEM
......is delicately balanced by a very sophisticated feedback
regulation and control system

• Prolonged immune deficiency can lead to infection, frequent

sickness, lack of vigor and energy and impaired metabolism.

• On the other hand, chronic activation of immune system can

also lead to certain autoimmune conditions such as arthritis,
lupus, nephritis, allergy, etc.
 
Immune Cells Recognize and Destroy:
Pathogens and Altered Cells
Chemical message alerts Immune cell
immune system that an “swallows”
invader is present foreign invader
 REISHI MUSHROOM
Reishi (Ganoderma lucidum) mushroom
is a fungus occurring as a shelf-like form
on the sides of trees and stumps in
densely wooded mountains with high
humidity and low light.

The spores of Reishi have such tough

outer husks that germination is next to
impossible, which accounts for its rarity.
 TYPES OF REISHI
There are 62 types of Reishi, of which six are most common:

RED BLACK
BLUE WHITE
YELLOW PURPLE

RED Reishi is preferred because it can produce the highest

quality extract and has been subject to the most scientific
evaluation
 TRADITIONAL USE
Reishi, also known as Lingzhi, is one of the most valued herbal products in
Traditional Chinese Medicine (TCM)

Reishi’s earliest herbal remedies were recorded between

206 B.C. - 8 A.D.

In Taiwan, families often give

Reishi to their aging grandparents
 CULTIVATION OF REISHI
In 1971, Yukio Naoi, a researcher of the Kyoto University in
Japan, successfully developed the artificial cultivation of
Reishi, which resulted in reproducible and consistent
production of Reishi.
 REISHI SPORES
• These highly active substances are the essence of Reishi.
• They are the reproductive cells that are released at maturity.
• However, Reishi spores are protected by an extremely hard shell
which prevent us from optimally absorbing the actives.
Compounds Identified in Reishi Mushrooms
Compound Function
Polysaccharides Improves immunity, reinforces liver function, and
stimulates insulin secretion
Triterpenes Nourishes the liver, anti-allergy, anti-inflammation,
maintains cholesterol, and eases pain
Nucleosides Inhibits plaque agglutination, prevents thrombus
formation
Fatty Acids Inhibits histamine release
Amino Acids, Replenishes nutrients
Vitamins, Minerals
RESEARCH FINDINGS:
REISHI MUSHROOM & EXTRACTS
• Cell support
• Immune dysfunction-related diseases
• Liver protection
• Nervous system dysfunction
• Cardiovascular protection and blood sugar support
 CLINICAL STUDIES ON REISHI
Reishi stimulates the immune system’s ability to recognize
pathogens and altered cells

Reishi provides complementary therapy to promote health

and longevity

• stimulates the formation of antibodies

• stimulates the ability of proliferation of immune cells
• modulates the function of T cells and NK cells

Wang SY, et al. International Journal of Cancer 1997;70(6):699-705. Lu Z, Lin ZB. 1994 International Symposium on
Ganoderma Research, October 24-26, 1994, Beijing Medical University, Beijing , China, Program and Abstracts, p. 82.
Kupin, V. (1992). The 4th International Symposium on Ganoderma lucidum, Hyatt Regency hotel, June 10, 1992, Seoul, Korea,
Program and Abstracts, pp. 36-39. Yang QY, Wang, M. M. (1996). 1996 Taipei International Ganoderma Research Conference,
Taipei International Convention Center (TICC), August 15-15, 1996, Abstracts, Special Lecture.
 Optimal Immune System Support

* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
  Uses the best Reishi species:
RED Reishi or Ganoderma lucidum
 Use of the best Reishi cultivation method:
solid tree trunk, organic cultivation for
120-200 days
 Free of heavy metals and
unwanted microbial
contamination

* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
 Uses Pharmanex’s
proprietary
manufacturing
process
to extract active
components from
Reishi
* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
 Cracked Reishi Spores

Reishi spores 100% Cracked spores

— 3000X magnification under an electronic microscope

* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Proprietary Formula
• Contains Reishi spores (100% cracked)
• Standardized to
– 6% Reishi triterpenes
– 13.5% Reishi polysaccharides
 REISHIMAX CLINICAL STUDIES
A comparative study demonstrated enhanced
immune functions by ReishiMax:
• Increased serum antibodies*
• Stimulated proliferation of immune cells*
• Modulation of the T cell functions*
• Enhanced the NK cell functions*

* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
 ReishiMax enhances cell-mediated
immune functions*
5000
p<0.001 by ANOVA
Interleukin-2 (pg/ml)

4000
+822% +799%
3000

2000
+405%
p=0.12
1000

0
Placebo 0.585 1.170 2.925 0.585 (g/kg)
ReishiMax GLP Other
Reishi
By Medical Institute at National Taiwan University
* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
 Higher Amount of Actives
mAU Other Reishi product
GA
200

100

0 10 20 30 40 50
min

mAU ReishiMax GA

Ganoderol acid DM-std

Ganoderol B
100

50

0 10 20 30 40 50
min

* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
 HIGHER SOLUBILITY
90%
90%
80% 71%

70%
60% 51%

50%
40%
30%
20%
10%
0%
ReishiMax Reishi A Reishi B
By Pharmanex Research Center at Shanghai Medical University
* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
 COMPETITIVE ADVANTAGE
 6S process
 Best natural Red Reishi species
 Organic cultivation
 Cracked spores
 Proprietary manufacturing
technology
 Highest level of actives on the
market
 Scientifically proven

* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
 RECOMMENDED USAGE
Take twice daily with meals:
• 1 capsule each time for health
maintenance
• 2 capsules each time for
immune modulation
Safe and well tolerated at the
recommended dosage

* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
 Taken together, ReishiMax and Tegreen 97
provide a comprehensive cellular health
maintenance program*

* These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
THANK YOU