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  • Liver PA

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    Elena Cristina
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    The liver is the largest gland in the body, weighing about 1500 grams in adults. It performs both internal and external secretion functions, as the same hepatocyte cells are responsible for both. The liver is divided into lobes that are functional units, with classical lobes containing hepatocytes and central veins, and portal lobes located around the porto-biliary spaces where bile is secreted into ducts from the portal spaces. Liver damage occurs in acinus patterns based on the distance of hepatocytes from blood vessels, with hypoxic or toxic lesions appearing farther from vessels first.

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    liver PA

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    The liver is the largest gland in the body, weighing about 1500 grams in adults. It performs both internal and external secretion functions, as the same hepatocyte cells are responsible for both. The liver is divided into lobes that are functional units, with classical lobes containing hepatocytes and central veins, and portal lobes located around the porto-biliary spaces where bile is secreted into ducts from the portal spaces. Liver damage occurs in acinus patterns based on the distance of hepatocytes from blood vessels, with hypoxic or toxic lesions appearing farther from vessels first.

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    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    3 views26 pages

    Liver PA

    Uploaded by

    Elena Cristina
    The liver is the largest gland in the body, weighing about 1500 grams in adults. It performs both internal and external secretion functions, as the same hepatocyte cells are responsible for both. The liver is divided into lobes that are functional units, with classical lobes containing hepatocytes and central veins, and portal lobes located around the porto-biliary spaces where bile is secreted into ducts from the portal spaces. Liver damage occurs in acinus patterns based on the distance of hepatocytes from blood vessels, with hypoxic or toxic lesions appearing farther from vessels first.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
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    of 26

    LIVER

    https://liverfoundation.org/for-patients/about-the-liver/the-progression-of-liver-disease/
    Let’s repeat!

    -the most voluminous gland of the body 1500 gr


    - amphicrine gland:
    -the same cell - the hepatocyte - performs a function of internal and external
    secretion
    Hepatic lobe = morpho-functional unit
    Classical lobe: hepatocyte+CLV
    Portal lobe: located around the porto-biliary space, whose biliary secretion is
    eliminated in a bile duct from the port space
    Hepatic acinus-> Acinus is functionally based on hepatocyte lesions due to
    hepatic hypoxia or toxic lesions, depending on the distance from the blood
    vessel.
    LIVER
    Stain HE
    3

    LIVER
    Stain Trichromic
    1 centrolobular vein
    2. Hepatic lobe
    3. Portal space

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