Professional Documents
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Module 6A
Module 6A
Resource Speaker
Designation
Inpatient Therapeutic Care
(ITC)
Learning objectives
At the end of the module, you will be able to:
• Explain reductive adaptation
• Assess patients for admission to ITC
• Triage SAM patients to emergency and non-emergency cases
• Give appropriate medications for ITC and their correct administration
• Administer nutritional management of SAM children 6-59 months
• Administer nutritional management of SAM children <6 months
• Orient the mother/caregiver in the care of her child with SAM
• Monitor each child for signs of deterioration in each Phase
• Assess a child’s readiness for discharge
Session 1.
Pathophysiology of
severe acute malnutrition
Reductive Adaptation
Malnourished children have adapted to low food intake by:
• Using energy and nutrients more efficiently
• Doing less work
• The reduced activity affects all the organs and cells in a
malnourished child’s body
• Causes very profound effects on body functions
Children with malnutrition do not show usual signs and
symptoms and the usual life-saving actions may be
dangerous in the malnourished child.
Reductive Adaptation
Acute malnutrition involves internal processes that lead to an
altered metabolism and involving the disruption of:
1. Cardiovascular system
2. Gastro-intestinal system
3. Liver function
4. Genitourinary system
5. Immune system
6. Endocrine System
7. Circulatory system
Muscle Muscle fibers become thin and
Function weak
Slower muscle contraction &
relaxation
Intestinal Atrophy of intestinal villae High volume &
Function Reduction in enzymes to absorb concentrated food can
carbohydrates cause diarrhea
Heart Function Reduced cardiac output Easy to precipitate heart
failure by fluid overload
Kidney Reduced renal blood flow Sodium concentration
Function Glomerular Filtration Rate(GFR) is may increase to
reduced dangerous level
Sodium excretion is impaired
Immune & Reduced (antibody-mediated & 95% of SAM have
Inflammatory cell-mediated immunity are systemic infection
Functions diminished) Blood WBC count is
unreliable
Breathing,
Followed by Amoxicillin Orally / NGT 4 - 9.9kg = 250mg Twice daily for 5 days
10 - 13.9kg = 500mg
14 - 19kg = 750 mg
*Where there is amoxicillin resistance give Cefotaxime (IM 50mg/kg once daily) for 2 days then
give amoxicillin-clavulanic acid combination for 5 days
Routine Medications for SAM in
Phase 1 / Stabilization
Antimalarials
•Follow national protocol
•Caution: some antimalarials are toxic in the
SAM child – avoid amodiaquine
•NO Quinine in the first two weeks of treatment
Medications NOT for Phase 1
Anti-helminthics
• Absorbed through gut and generates active metabolites in the liver
• Would be ineffective as SAM child with poor gut and liver function
• Not given immediately but given later during treatment
Iron
• Increases risk of death by increasing risk of sepsis
• Given only in Phase 2
Zinc
• Only given in Phase 1 if commercial therapeutic feeds not available
AND
• Child has diarrhea
Test yourself!!
True or False.
1. SAM patients need sodium supplementation.
FALSE
2. All children with SAM are presumed to have a bacterial infection.
TRUE
3. Iron supplementation is given during Phase 1 treatment in ITC.
FALSE
1. Phase 1
Stabilization
2. Transition
3. Phase 2
SAM ITC
Phase 1 Stabilization
Discharge
(Transfer) to OTC
SAM ITC Phase 2
*low in protein, fat and sodium and *nutritional value equal to RUTF *consists of a peanut-based paste,
rich in carbohydrates with sugar, vegetable fat and
*used as therapeutic milk for <6 skimmed milk powder, enriched
months old infants with vitamins and minerals
Phase 1/Stabilization
https://www.youtube.com/watch?v=_yiIVpVA4Zc&feature=
youtu.be
When F-75 is not available
• There are alternative recipes
• Or use diluted F-100
• Commercial milk formula is NOT a suitable substitute
≥ 5kg 6
⅓ packet 1 ¾ to 2 packets
Pointers on
Preparing RUTF
Demonstrate proper
handwashing with
soap and water
Preparing RUTF to eat
Measure the
portions
One fourth
Tear RUTF packet Fingers mark the portion
as the child eats
Or caregiver gives a small amount on he
finger
On RUTF
If RUTF not consumed --
• Offer F-75 therapeutic milk
• Eating of RUTF and F-75
should not take more than 1
hour
• Store RUTF in a cool dry
place
• Offer RUTF at
the next feeding
until child
consumes full
amount
• Once consistently
eating full
amounts, further
increase amount
Re-assess, re-assess
• Change the treatment regimen if the child’s appetite does not
improve over 2-3 days (they do not eat the required RUTF
amount)
• Change the diet to F-100 if the child is stable but the appetite
does not improve after 3 days in the Transition Phase →
continue to Phase 2 inpatient care
Fully transitioning to OTC
The child is ready to continue nutritional
rehabilitation at home with OTC when:
• At least 75% of full RUTF amount is
eaten in 24 hours
• No other issues identified during
monitoring
• If conditions are fulfilled, discontinue F-75
and give RUTF plus water or
breastfeeding
• Refer to OTC or back to the OTC which
referred the child
Referral Form to ITC or OTC
Transition to Phase 2 using F-100
Do this when:
1.Child on RUTF in preparation for outpatient care, clinically stable but
appetite not improving
5.When 90% of F-100 ration taken orally and no other issues → Phase
2
Preparing F-100
Prepare amount of F-100 milk needed
https://www.youtube.com/watch?v=_yiIVpVA4Z
c&feature=youtu.be
Phase 2
• Caloric intake increased to 200 kcal/kg/day using F-100
therapeutic milk
1. Anthropometry
2. Weight Graph
3. Feeding
4. Feeding monitoring
Surveillance in Phase 1
After every feeding Record any breastfeeding taken before the therapeutic milk
session of Record the amount of therapeutic feed taken carefully on the
therapeutic milk, the therapeutic surveillance sheet
medical staff should: For infants < 6 months: note the amount of therapeutic milk given
Every 12 hours Measure and record the child’s temperature, pulse rate and respirations
Everyday Indicate the prescription for therapeutic milk, measure and record the
weight , measure and record the level of edema, record symptoms such
as cough, indicate if the child has an NGT, for infants < 6 months:
assess breastfeeding practice
The condition may occur when after fasting more than one week, with
rapid ingestion and large amounts of food develops:
acute weakness or “floppiness”, lethargy, delirium, neurological
symptoms, acidosis, muscle necrosis, liver and pancreatic failure,
cardiac failure, sudden unexpected death
Reasons for deterioration in Transition
Phase:
Re-activation syndrome - occurs when a previously undiagnosed
infection becomes apparent.
•Result of the recovery of the immune and/or inflammatory system rather
than the development of a newly acquired infection
•Treatment is according to national protocol except where modified by
other protocols in these guidelines
Reasons for deterioration in Transition
Phase:
Osmotic diarrhea - resulting from a change in diet (less common with
low osmolarity feeds)
Aspiration of food - through improper feeding technique (children with
SAM have weak muscles and swallow slowly. This makes them prone to
choking, with liquid or food particles entering their airways and and
developing aspiration pneumonia).
Nosocomial infection – child contracting illness from other patients
Inappropriate prescription / use of medications – some medicines may
be harmful to child due to abnormal physiology in SAM child
Switch from Transition (RUTF) to Phase 2 F-100 if:
• Stable but appetite is not improving after three days in Transition
• Transition onto RUTF can be attempted again after a couple of days
Be vigilant for any of the following signs that the child is not coping with the transition:
• Rapid increase in the size of • Any significant re-feeding diarrhea
the liver* involving weight loss
• Any sign of fluid overload (i.e. • Any complication arising which
increasing respiratory and necessitates intravenous fluids
pulse rates, increasing edema • Edema not reducing, any increasing
and puffy eyelids, visible neck edema or edema developing when
veins)* it was previously absent
*If these signs occur, stop fluids immediately and reassess after one hour)
Session 9
Monitoring and Referral in
Phase 2
Surveillance in Phase 2
• Continue monitoring until recovery.
• Observations should be recorded
systematically on the Therapeutic
Surveillance Sheet
• Refer back to Phase 1 care with F75 or
transition if:
▪ There is deterioration in the nutritional status
of the child
▪ Do a thorough assessment/reassessment of
the child’s treatment
Surveillance in Phase 2 After
transition,
Daily Record RUTF or F100 intake after each feed
Observations Measure weight
monitor
Assess edema progress by
Count the number of breaths in a full minute
Measure heart rate
rate of weight
Measure temperature gain:
Assess clinical status (vomiting, diarrhea, dehydration,
cough)
Assess nutritional status against discharge criteria Weigh the
child every
Weekly Measure MUAC morning
observations
before
Two-weekly Measure height/length feeding, &
observations
plot the
weight.
Calculating weight gain
This example is for weight gain over 3 days. Classify the weight gain as:
•Current weight of the child in grams = 6300 g •poor (< 5 g/kg per day), the
•Weight 3 days ago in grams = 6000 g child requires a full re-
assessment
Step 1: Calculate weight gain in grams
•moderate (5–10 g/kg per
6300–6000 = 300 g day), check whether the
Step 2: Calculate average daily weight gain intake targets are being met
300 g ÷ 3 days = 100 g/day or if infection has been
overlooked
Step 3: Divide by child's average weight in kg:
•good (> 10 g/kg per day)
100 g/day ÷ 6.15 kg = 16.3 g/kg per day
Pocket Book of Hospital Care for Children: Guidelines for the
Management of Common Childhood Illnesses. 2nd edition.
Geneva:
Session 10: Discharge
Criteria to Start Transition Phase to OTC:
Category Criteria
Child aged 6 to 59 months Medical complications resolved (or chronic
conditions controlled)
AND
edema subsiding (must have reduced to at least
+2)
AND
appetite for RUTF (must be able to eat at least
75% of outpatient ration)
*There is no anthropometric criterion for discharge when transitioning from ITC to OTC because nutritional
rehabilitation is continued and completed in OTC.
Category Discharge Criteria from Transition to OTC
• Grade of edema
• Ration of RUTF given (number of
packets on discharge)
• Medications received and medicines Children discharged from ITC are
PRIORITY for outreach follow-up in
to be continued after discharge their first week in the OTC
• Clinical condition on discharge
Discharge procedure to OTC
Step 7 Record the child as a “discharge to outpatient care”
in the tally sheet/monthly report.
Child aged 6 to 59 Admitted on MUAC, edema, MUAC ≥ 125mm (12.5cm) for 2 consecutive visits
months or both MUAC and WFH Z- AND
score No edema for 10 days AND Clinically well
Infants < 6 months Child is gaining weight more than 5g/kg/day on breast milk for 3
consecutive days**
AND
edema is absent
AND
Clinically well & childhood immunizations have been checked
Discharge Procedure from ITC:
Step 1 Explain to the caregiver that their child has recovered sufficiently
and congratulate them.
On Day 3, Ana’s appetite increased. She finished the ration of F75 milk
each feeding and would ask for more.
4. What are the criteria that signal the readiness to transition?
a. medical complications are resolving
b. appetite returns
c. edema is reducing
d. all of the above
Case 1. Ana
Ana was a reluctant eater, but she finished most of her feeds and
continued 4-hourly feeds (6 feeds per day) on Day 2. At two feeds, she
took less than 75% of the amount offered, but then she took more at the
next feeds.
3. Does Ana need an NGT for feeding? (Yes or No)
On Day 3, Ana’s appetite increased. She finished the ration of F75 milk
each feeding and would ask for more.
4. What are the criteria that signal the readiness to transition?
a. medical complications are resolving
b. appetite returns
c. edema is reducing
d. all of the above
Case 1. Ana
Ana was a reluctant eater, but she finished most of her feeds and
continued 4-hourly feeds (6 feeds per day) on Day 2. At two feeds, she
took less than 75% of the amount offered, but then she took more at the
next feeds.
3. Does Ana need an NGT for feeding? (Yes or No)
On Day 3, Ana’s appetite increased. She finished the ration of F75 milk
each feeding and would ask for more.
4. What are the criteria that signal the readiness to transition?
a. medical complications are resolving
b. appetite returns
c. edema is reducing
d. all of the above
Case 1. Ana
You decided that Ana is ready for transition. The RHU in her vicinity has
a functional OTC.
By Day 6-7, what would you consider to decide that Ana is ready to
be discharged to OTC?
a.At least 75% of full RUTF amount is eaten in 24 hours
b.No other issues identified during monitoring
•a and b
Case 1. Ana
You decided that Ana is ready for transition. The RHU in her vicinity has
a functional OTC.
By Day 6-7, what would you consider to decide that Ana is ready to
be discharged to OTC?
a.At least 75% of full RUTF amount is eaten in 24 hours
b.No other issues identified during monitoring
c.a and b
Case 1. Ana
You decided that Ana is ready for transition. The RHU in her vicinity has
a functional OTC.
By Day 6-7, what would you consider to decide that Ana is ready to
be discharged to OTC?
a.At least 75% of full RUTF amount is eaten in 24 hours
b.No other issues identified during monitoring
c.a and b
Case 1. Ana
You decided that Ana is ready for transition. The RHU in her vicinity has
a functional OTC.
By Day 6-7, what would you consider to decide that Ana is ready to
be discharged to OTC?
a.At least 75% of full RUTF amount is eaten in 24 hours
b.No other issues identified during monitoring
c.a and b
Case 2a. Marcia
Marcia is a 38 months old girl with weight 8.6 kg, height
is 85.5 cm.
Her WFH Z score is < -3 SD. MUAC is 10.9 cm. She
had bilateral edema with poor appetite.
1. What is the grade of her edema?
2. What is your diagnosis?
2.How much calories will this give her per kg body weight?
3.How much volume would you give her at each meal if you plan
to give her 6 meals/day? She is now 8.8kg
Case 2b. Marcia
TRANSITION
There is no OTC near where Marcia lives. You plan to transition her
to what phase of nutritional management?
2.How much calories will this give her per kg body weight?
3.How much volume would you give her at each meal if you plan
to give her 6 meals/day? She is now 8.8kg
Case 2b. Marcia
TRANSITION
There is no OTC near where Marcia lives. You plan to transition her
to what phase of nutritional management?
1.What type of therapeutic feeding will you give Marcia?
Transition to Phase 2 using F100
2.How much calories will this give her per kg body weight? 130
Cal/kg/day
3.How much volume would you give her at each meal if you plan
to give her 6 meals/day? She is now 8.8kg
Case 2b. Marcia
TRANSITION
There is no OTC near where Marcia lives. You plan to transition her
to what phase of nutritional management?
1.What type of therapeutic feeding will you give Marcia?
Transition to Phase 2 using F100
2.How much calories will this give her per kg body weight? 130
Cal/kg/day
3.How much volume would you give her at each meal if you plan
to give her 6 meals/day? She is now 8.8kg 180 ml
Case 2b. Marcia
On Day 5, her mother tells you that Marcia eats all the therapeutic
milk on her own and seems to want for more.
5.To what calorie intake per kg body weight will she now be
increased?
6.How much volume of feed will you give per meal for 5 feeds
per day? She is now 9 kg.
Case 2b. Marcia
On Day 5, her mother tells you that Marcia eats all the therapeutic
milk on her own and seems to want for more.
5.To what calorie intake per kg body weight will she now be
increased?
6.How much volume of feed will you give per meal for 5 feeds
per day? She is now 9 kg.
Case 2b. Marcia
On Day 5, her mother tells you that Marcia eats all the therapeutic
milk on her own and seems to want for more.
5.To what calorie intake per kg body weight will she now be
increased? 200 kCal/kg/day
6.How much volume of feed will you give per meal for 5 feeds
per day? She is now 9 kg.
Case 2b. Marcia
On Day 5, her mother tells you that Marcia eats all the therapeutic
milk on her own and seems to want for more.
5.To what calorie intake per kg body weight will she now be
increased? 200 kCal/kg/day
6.How much volume of feed will you give per meal for 5 feeds
per day? She is now 9 kg. 270mL
Case 2b. Marcia
DISCHARGE
7. What criteria will help you decide when she is ready for
discharge? Encircle the letter of the correct answer.
7. What criteria will help you decide when she is ready for
discharge? Encircle the letter of the correct answer.
• F-75 and F-100 are now supplied in 400g canisters allowing for
longer shelf life of 4 weeks when opened
• Each canister comes with a specifically developed scoop (white for
F-75 and blue for F-100) that allows smaller amounts of therapeutic
milk to be prepared
• Smaller amounts of freshly made up milk reduces wastage and
minimizes the risk of contaminated feeds being given to children
• Using the corresponding look-up tables, the amount of therapeutic
milk to be prepared will determine the number of scoops and amount
of boiled water needed
Reference Table for F-75
F-75
Level Scoop Quantity of Water (ml) Approximate Feed Volume (ml)
1 25 ≈28
2 50 ≈56
4 100 ≈112
8 200 ≈224
10 250 ≈280
20 500 ≈560
Whole canister of 400g 2200 ≈2480
1 25 ≈29
2 50 ≈58
4 100 ≈117
8 200 ≈234
10 250 ≈290
20 500 ≈580
Whole canister of 400g 1850 ≈2158
1 25 28
2 50 56
4 100 112
8 200 224
10 250 280
Since we will 20
be needing 56ml of feed, we500 will need to prepare 2 scoops
560 of F-75 and
Whole50ml
canisterof
of water
400g to produce an approximate
2200 feed volume of2480
56ml
1 25 28
2 50 56
4 100 112
• From this table, we will need to add 2 scoops of F-75 to the 50ml of boiled water in the feeding
cup to make 56 ml of F-75 feed
• Do not press the scoop on the side of the can as the scoop will become too tightly packaged
• Using the rim of the can of flat edge of a spoon, level off the excess powder
• Adding more or less powder than instructed can make the children ill.
• Make sure scoop does not come into contact with moisture or water.
• Replace scoop in can and close securely.
Preparing a cup feed of F-75
• Mix powder and water thoroughly by stirring with a spoon. Stir
until consistency is smooth and lumps are dissolved. Be careful to
avoid scalding.
• Cool to feeding temperature ≤37ºC.
• You may use a cooling bowl to reduce the temperature of the
feed. Ensure that the feed does not come into contact with the
water bath.
Preparing a cup feed of F-75
• When cooled, give the feed to the child. Throw away
any milk not consumed within 2 hours after
preparation.
• Dry the outside of the feeding cup and label.
• Include on the label the type of therapeutic milk, the
patient’s name, date and time of preparation, amount
of feed required, and preparer’s name or initials
• Check temperature of the feed before giving to the
child. Drop a small amount of feed to the wrist,
without putting the cup in contact with the skin.
• If it is at room temperature, then it is ready to give to
the child.
Preparing a cup feed of F-75
Options for feeding, use:
1. Cup and saucer
• The child drinks from cup
• Any spillage while drinking will be caught with the saucer
• Spilled therapeutic milk will be returned to the main cup used by
the child
2. Nasogastric tube
Give the feed to the child, and then throw away any milk
not consumed within 2 hours after preparation
Preparing a cup feed of F-100
• Follow the same procedure for F-75, noting the
required amount to be prepared and following the
appropriate F-100 look up table to determine scoops
and mls of water needed
• Make sure to use the correct blue scoop for F-100
Preparing a batch of cup feeds ( if more
than one patient)
• When you have more than 1 SAM patient, it will be
necessary to prepare more than 1 cup feed
simultaneously.
• A larger batch of therapeutic milk can be made
and transferred to individual feeding cups
• Take note that therapeutic feeds are more
susceptible to contamination in large, open
containers
• Large volume of feeds will take a longer time to
cool down, leaving potential for growth of harmful
bacteria if not prepared properly
• Preparing batches of milk will save time, but it is
important to decant the milk into serving cups
immediately to avoid bacteria growth
Preparing a batch of cup feeds
• After determining the total amount of feeds that need to be prepared,
prepare the appropriate amount of water and therapeutic milk needed
based on the look up table
• Observe the same procedures in sterilizing the materials, boiling the
water, and mixing of the powder
• After preparation, immediately pour the appropriate amount of feeds in
the prepared feeding cups and give to the children