Mock Practical Session

Section A
Dr Modupe Kuti
FWACP (Lab Med)
 Question 1
Result A Result B
Urine Volume mL 25 2000
Urine Creatinine (conc.) mg/dL 23 23
Urine Creatinine (24hr) mg - 460
Urine Albumin (conc.) mg/dL 6 6
Albumin Creatinine Ratio mg/g 261 -
Albumin Excretion Rate g/24 hr - 0.12

a) How will the reference interval for the urine creatinine (24hr) be determined?

b) What is the rationale for the above?

c) What is the basis for the measurement of urine creatinine for result A?

d) How were the samples used in Result A and Result B collected?

 Question 1
Result A Result B
Urine Volume mL 25 2000
Urine Creatinine (conc.) mg/dL 23 23
Urine Creatinine (24hr) mg - 460
Urine Albumin (conc.) mg/dL 6 6
Albumin Creatinine Ratio mg/g 261 -
Albumin Excretion Rate g/24 hr - 0.12

a) How will the reference interval for the urine creatinine (24hr) be determined?

b) What is the rationale for the above?

c) What is the basis for the measurement of urine creatinine for result A?

d) How were the samples used in Result A and Result B collected?

 Question 2
• A 45-year-old man was referred to the outpatient clinic with hypertension which is difficult
to control. His blood pressure was 190/100mmHg. For the past 4 months, it was noted
that his plasma Potassium has ranged between 2.6 and 2.9 mmol/L. There was no other
remarkable medical history. His physician requests for a Plasma Aldosterone- Renin
Ratio (ARR)

a) What is the clinical usefulness/utility of the requested test?

b) State 2 important precautions to be observed before this test is conducted

c) How is plasma renin level determined?

d) List 2 follow up tests that may be indicated with a positive ARR

 Question 2
• A 45-year-old man was referred to the outpatient clinic with hypertension which is difficult
to control. His blood pressure was 190/100mmHg. For the past 4 months, it was noted
that his plasma Potassium has ranged between 2.6 and 2.9 mmol/L. There was no other
remarkable medical history. His physician requests for a Plasma Aldosterone- Renin
Ratio (ARR)

a) What is the clinical usefulness/utility of the requested test?

b) State 2 important precautions to be observed before this test is conducted

c) How is plasma renin level determined?

d) List 2 follow up tests that may be indicated with a positive ARR

 Question 3
• Review the information below from an EQA report
SDI – Standard Deviation Index

% D – Percentage Deviation

a) What is the difference between overall performance and instrument performance?

b) How is SDI calculated?
c) How is SDI interpreted
d) What is your conclusion about this laboratory’s performance from this report
 Question 3
• Review the information below from an EQA report
SDI – Standard Deviation Index

% D – Percentage Deviation

a) What is the difference between overall performance and instrument performance?

b) How is SDI calculated?
c) How is SDI interpreted
d) What is your conclusion about this laboratory’s performance from this report
 Question 3
• Review the information below from an EQA report
SDI – Standard Deviation Index

% D – Percentage Deviation

a) What is the difference between overall performance and instrument performance?

b) How is SDI calculated?
c) How is SDI interpreted
d) What is your conclusion about this laboratory’s performance from this report
 Question 4
• Study the electrophoretograms below

I.

II.

III.

IV.
a) Identify all the bands present in the first strip (Normal) , from left to right
b) Which of these patterns would you seen in a patient with nephrotic syndrome?
c) Explain the changes seen in the electrophoretogram chosen in b) above
d) Indicate a likely diagnosis in the other 2 strips
 Question 4
• Study the electrophoretograms below

I.

II.

III.

IV.
a) Identify all the bands present in the first strip (Normal) , from left to right
b) Which of these patterns would you seen in a patient with nephrotic syndrome?
c) Explain the changes seen in the electrophoretogram chosen in b) above
d) Indicate a likely diagnosis in the other 2 strips