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TITLE OF THESIS

A CROSS SECTIONAL STUDY ON THE


PREVALENCE OF THYROID DISORDERS
AMONG ADULTS IN THE URBAN
POPULATION OF DELHI
PROTOCOL PRESENTATION BY
DR.MOHD ASLAM
FIRST YEAR POSTGRADUATE(2022-2025)
DEPT. OF PHYSIOLOGY
MAULANA AZAD MEDICAL COLLEGE
& ASSOSIATED HOSPITALS
NEW DELHI110002
GUIDE AND CO-GUIDE
NAME OF SUPERVIOSR. NAME OF CO-SUPERVISOR,

DR. AARTI SOOD MAHAJAN DR.M.MEGHACHANDRA SINGH

Director Professor & Head Director Professor & Head

Department of Physiology Department-Community and Family Medicine

Maulana Azad Medical College Maulana Azad Medical College

New Delhi – 110002. New Delhi -110002.

CO SUPERVISOR CO-SUPERVISOR
DR. DAYARAM HALDWANI DR. BINITA GOSWAMI
Director Professor & Ex-HOD Professor
Department of Physiology Department of Biochemistry
Maulana Azad Medical College Maulana Azad Medical College
New Delhi -110002 New Delhi -110002
INTRODUCTION
• Thyroid dysfunction is one of the most common endocrine
diseases seen in clinical practice.
• It may include hyporthyroidism,subclinical hypothyroidism and
Hyperthyroidism,subclinical hyperthyroidism and
• The prevalence of thyroid dysfunction varies by age, sex, race,
and geographically1,2.
• Abnormal thyroid function has important ramifications on health
issues including metabolism,bone health and mental health3.
• Current estimates of the frequency of thyroid dysfunction are
largely deduced from data in middle-aged populations4,5
• There are limited available data on the prevalence of thyroid
dysfunction in adults in urban indian population.
INTRODUCTION
• The Prevalence of hypothyroidism is variable because being
studies have differed significantly with regard to population
age range, geographic position, race and environmental
factors( salutary iodine and goitrogen input),
• Inheritable characteristics of study population, and criteria
used to define presence and degree of thyroid disease6.
• At present, the overall global Prevalence of hypothyroidism is
4.6% while in India, it's reported to be around10.957. The
Colorado Thyroid Disease Prevalence Study of,862 state
residers reported an elevated serum TSH concentration in
9.5% of all individualities and in 8.9% of those who weren't
formerly taking thyroid hormone8.
INTRODUCTION
• While multiple studies have examined associations of race,
commerce, BMI, dyslipidemia, heart rate, glycemic control,
order function and smoking with thyroid hormone situations in
middle-aged cohorts5.
• In an epidemiological study carried out from Cochin,
subclinical and overt hyperthyroidism were present in about
1.6% and1.3% independently of the subjects who took part in
the survey9.
• In a sanitarium- rested study conducted in Pondicherry among
the women population, subclinical and overt hyperthyroidism
were present in1.6% and1.2% of subjects10.
INTRODUCTION
• It is essential to pierce newer population and newer
geographic areas of the country which have yet remain
unexposed in analogous epidemiological checks to
comprehend the nature of thyroid conditions and their
associations with thyroid autoimmunity and other common
comorbidities.
• Lacunae in existing literature-
• There is paucity of information on the Prevalence of Thyroid
Dysfunction/ Thyroid disorders among adults in the urban
community setting in India.
AIMS AND OBJECTIVES

• AIMS AND OBJECTIVES


• 1)To assess the prevalence of thyroid dysfunction among
adults residing in an urban community of Delhi.
• 2)To study the association of anthropometric and biochemical
Parameters (RBS, Lipid profile) in these subjects with thyroid
profile of study participants.
• 3)To increase awareness of thyroid illness in community.
MATERIALS AND METHODS

• MATERIALS AND METHODS


• STUDY SETTING: This study would be carried out in the
Department of Physiology in association with the Department
of Community and department of biochemistry, Maulana Azad
Medical college and Associated hospital, New Delhi.
• STUDY DESIGN
• Community-based cross-sectional study.
STUDY AREA

• STUDY AREA
• The study will be conducted in the field practice area of Urban
Health centre, Gokalpuri attached to the Department of
Community Medicine, Maulana Azad Medical College, New
Delhi. The population of the Gokalpuri urban area is 29,242
residing in 7961 households. It has 4 blocks (A, B,C,D).
• STUDY PERIOD
• Study will be conducted for a period of one year.
STUDY POPUL ATION-

• STUDY POPUL ATION-


• SUBJECT SELECTION
• INCLUSION CRITERIA
– Adults aged between 18 to 59 yrs.
– Both genders male and female.
– Both undiagnosed and diagnosed patients with thyroid
disorders
STUDY POPUL ATION-

• EXCLUSION CRITERIA.
– Not willing to participate.
– Geriatric population above 60 years.
– Pregnant women.
• PRIMARY OUTCOME
• Proportion of adults having thyroid dysfunction.
• SECONDRY OUTCOME
• Increasing awareness of Thyroid illness in community.
SAMPLE SIZE

• SAMPLE SIZE

• Sample size is calculated using the following formula



• N = Z α2 p q
• L2
• Where,
• Zα = 1.96, Value of the standard normal variate corresponding to the
level of significance, Alpha = 5%,
• N = Sample Size,
• p = prevalence,
• q = 100-p,
• L = Relative Error.
MATERIALS AND METHODS

• Based on a previous study conducted by P Manash et al, the


prevalence of thyroid dysfunction is taken as 33.98 11. The
sample size is calculated as follows-
• p= 33.98
• q = 100-33.98=66.02
• L= Relative error 20% of p.
• Therefore, N= 1.96 x1.96 (33.98 X 66.02) =170
(6.79 X 6.79)

• Sample size has come out to 170 be with prevalence of 33.98.
We will take minimum 187 study participants in this study
considering 10% non-response rate.
MATERIALS AND METHODS

• DETAILED METHODOLOGY: The participants are


classified as definitions like- hypothyroidism: when serum T4
<4.6 μg/dL and TSH >4.2 μIU/mL;
• hyperthyroidism:when serum T4 >12.0 μg/dL and TSH <0.27
IU/mL; and
• SCH(Sub clinical Hypothyroidism):where normal serum T4
(4.6–12 μg/dL) and TSH >4.2 IU/mL.
DETAILED METHODOLOGY:
• STUDY INSTRUMENTS:
• Questionnaire:Pre-designed, semi-structured and pre-tested
interview schedule will be used.
• This will consist of identification data, which would include
name, age, place of residence, socio demographic factors
including occupation, educational level and monthly income12
history of thyroid dysfunction, if any, medical history,
menstrual history (females) and family history of thyroid
diseases.
• The data will be collected in Hindi after validation of the tool
for linguistic accuracy.
DETAILED METHODOLOGY:
• General physical examination: Head to toe examination for
any changes in texture of hair, skin will be done.
Anthropometric data (Height and weight) using standard
guidelines.
• BMI will be calculated for the study subjects using the height
and weight applying the formula: BMI=weight(kg)/height
(m2).
• According to WHO recommended cut-points for BMI
categories in Asian populations are as follows: <18.5, 18.5-
22.9, 23-27.4, and ≥27.5 for underweight, normal weight,
overweight and obese respectively13.
DETAILED METHODOLOGY:
• Weight will be taken using calibrated digital machine with
least count of 100 grams and height will be taken in standing
position against a wall,
• Height will be taken using a flexible, non-stretchable
calibrated measuring tape with least count of 1mm.
• Vital Statistics: Blood pressure and pulse rate. Blood pressure
will be measured by digital sphygmomanometer in sitting
position in study participant’s house.
DETAILED METHODOLOGY:
• Biochemical Investigations for thyroid function test (TSH, free
T3, free T4, Anti TPO antibodies) for this 3ml blood sample
(fasting)in Red top vacutainer is required and
• Lipid profile(direct LDL,HDL-Cholesterol will be measure by
Direct measure, PTA/MgCl2 methods,
• Total Cholesterol by Cholesterol oxidase,esterase peroxidase
methods and Triglicerides by Enzymatic endpoint methods.
• RBS with Glucose oxidase,hydrogen peroxidase method (for
this 2ml blood sample in Grey top vacutainer is required) will
be done from laboratory of department of Biochemistry.
METHODOLOGY / DATA COLLECTION:

• SAMPLING METHOD.
• Household will be the study unit.
• Total households are 7,961 in the study area, and the sample to
be covered is 180 households.
• The sampling interval is calculated by dividing total number
of households in the study are by the number of households
sampled i.e. 7961/187= ~ 43.
• Therefore, every 43rd house will be selected through
systematic random sampling method. The first household will
be selected randomly.
METHODOLOGY / DATA COLLECTION:

• A list of all the households will be obtained from the Urban


health centre/ Field functionaries. The sample will be collected
by house visits.
• The adults in the selected household will be interviewed using
a semi structured questionnaire after taking written informed
consent and explaining them the purpose of the study.
• In case there are more than one eligible adult in the household,
only one study subject will be chosen by the Kish Method.
METHODOLOGY / DATA COLLECTION:

• In case a household is found closed on the day of visit, three


visits will be made, then next household will be selected for
the study.
• First the contact numbers of all the subjects will be collected
in the previous day of survey. They will be requested for the
early morning fasting sample.
• After the completion of interview, 3 ml of blood will be
withdrawn from peripheral vein and collected in a plain (red
top)vacutainer by the researcher for the assessment of thyroid
hormone levels under all precautions.
METHODOLOGY / DATA COLLECTION:

• The blood samples collected will be placed in a collection box


after proper labelling and will be carried to the laboratory of
biochemistry department of M. Azad medical college with
utmost care(Temprature maintained icebox/carrier).
• In the laboratory the samples will be centrifuged to obtain
serum.
• TSH and thyroid hormone levels will then be measured using
CobasElecsys 401 Electrochemiluminescence Immunoassay
(Eclisa)and the reports will be collected from the laboratory on
next day.
• Anti Thyroperoxidase Ab(Anti-Tpo Ab) will be measured by
Enhanced Chemiluminescene Immunoassy.
METHODOLOGY/ DATA COLLECTION
• In addition, information and health education about Thyroid
releted disease will be provided to family in the form of Flash
card/Posters/ppts.
• The study subjects will be informed about the results. Those
who are found to have abnormal TSH or thyroid hormone
levels (free T3, free T4) will be referred to the physician
physician for medical management to Lok Nayak hospital.
STUDY PLAN-GANTT CHART
STATISTICAL ANALYSIS
• The collected data will be entered in MS-Excel and will be
analyzed using SPSS-version 25.
• Quantitative data will be expressed by mean and standard
deviation and significant level of differences between the mean
will be tested by Student’s’t’-test.
• For non-normal distribution, Mann Whitney U test will be
used.
• Qualitative data will be expressed by the percentages and
proportions and the significant level of differences between the
proportions will be tested by chi square test or fisher’s exact
test. These and/or other statistical test will be done.
• ‘p’ value of <0.05 will be considered statistically significance.
ETHICAL CONSIDERATION
• Approval of the Institutional Ethics Committee will be taken.
• The study does not include any method that goes beyond “less
than minimal” risk to the subject or their acquaintances.
• Each subject will be explicitly explained about the purpose of
the study by the investigator and written, informed consent will
be obtained from the subject before inclusion in the study.
• Privacy of subjects and confidentiality of responses will be
maintained and this will also be explained to the subject, before
inclusion.
• The benefit of knowledge and training will be provided to all
without bias.
REFERENCES
• 1.Ittermann T. Khattak, R. M. Nauck, M. Cordova C. M. & Volzke, H. Shif of
the TSH reference range with improved iodine supply in Northeast Germany.
Eur J Endocrinol 172, 261–267, https://doi.org/10.1530/EJE-14-0898 (2015).
• 2.Meisinger, C. et al. Geographic variations in the frequency of thyroid
disorders and thyroid peroxidase antibodies in persons without former thyroid
disease within Germany. Eur J Endocrinol 167, 363–371,
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• 7.Sethi B, Barua S, Raghavendra MS, Gotur J, Khandelwal D, Vyas U, et


al. The thyroid registry: Clinical and hormonal characteristics of adult
Indian patients with hypothyroidism. Indian J Endocrinol Metab
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• 8.Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. The
Colorado thyroid disease prevalence study. Arch Intern Med
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• 9. Usha Menon V, Sundaram KR, Unnikrishnan AG,
Jayakumar RV, Nair V, Kumar H. High prevalence of
undetected thyroid disorders in an iodine sufficient adult south
Indian population. J Indian Med Assoc. 2009;107:72–7.
• 10.Abraham R, Murugan VS, Pukazhvanthen P, Sen SK.
Thyroid Disorders In Women of Puducherry.Indian J Clin
Biochem. 2009;24:52–9.
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• 11.Institute of Medicine. Medicare Coverage of Routine
Screening for Thyroid Dysfunction. Washington, DC: The
National Academies Press .2003.https ://doi.org/10.17226
/https://doi.org/10.17226/10682. [Last accessed on 2019 Jan 12].
• 12.Ain SN, Khan ZA, Gilani MA. Revised kuppuswamy scale for
2021 based on new consumer price index and use of conversion
factors. Indian J Public Health. 2021 Oct-Dec;65(4):418-421. doi:
10.4103/ijph.ijph_1108_21. PMID: 34975091
• 13.World Health Organisation. Obesity: preventing and managing
the global epidemic. Report on a WHO Consultation on Obesity.
Geneva: WHO; 1997.
•THANK YOU
REFERENCES
• 5.Hollowell, J. G. et al. Serum TSH, T4, and thyroid antibodies in
the United States population (1988 to 1994): National Health and
Nutrition Examination Survey (NHANES III). The Journal of
Clinical Endocrinology & Metabolism 87, 489–499, https://doi.
org/10.1210/jcem.87.2.8182 (2002).
• 6.Bremner, A. P. et al. Age-related changes in thyroid function: a
longitudinal study of a community-based cohort. Te Journal of
clinical endocrinology and metabolism 97, 1554–1562,
tps://doi.org/10.1210/jc.2011-3020 (2012).
• 7. Institute of Medicine. Medicare Coverage of Routine Screening
for Thyroid Dysfunction. Washington, DC: The National Academies
Press. 2003. https://doi.org/10.17226/10682. [Last accessed on 2019
Jan 12].
REFERENCES
• 8.Sethi B, Barua S, Raghavendra MS, Gotur J, Khandelwal D,
Vyas U, et al. The thyroid registry: Clinical and hormonal
characteristics of adult Indian patients with hypothyroidism.
Indian J Endocrinol Metab 2017;21:302‑7.
• 9. FlynnRW, Bonellie SR, JungRT, MacDonaldTM,
MorrisAD, Leese GP, et al. Serum thyroid ‑stimulating
hormone concentration and morbidity from cardiovascular
disease and fractures in patients on long‑term thyroxine
therapy. J Clin Endocrinol Metab 2010;95:186‑93.
• 10.Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. The
Colorado thyroid disease prevalence study. Arch Intern Med
2000;160:526‑34.
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of the European Dialysis and Transplant Association - European
Renal Association, https://doi.org/10.1093/ndt/gfw301 (2016).
• 12.Peter PAS eds. Epidemiology of Thyroid dysfunction
hypothyroidism and hyperthyroididm. Thyroid International
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• 13.Baral N, Lamsal M, Koner BC, et al. Thyroid dysfunction in
eastern Nepal. South Asian J Trop Med Public Health 2002; 33:
638-641.
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overt hypothyroidism: effect on thyrotropin, prolactin, and thyroid
reserve and metabolic impact on peripheral target tissue.Am J Med
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• 20. Usha Menon V, Sundaram KR, Unnikrishnan AG, Jayakumar RV,
Nair V, Kumar H. High prevalence of undetected thyroid disorders in
an iodine sufficient adult south Indian population. J Indian Med
Assoc. 2009;107:72–7. PubMed
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• 21.Abraham R, Murugan VS, Pukazhvanthen P, Sen SK. Thyroid
Disorders In Women of Puducherry.Indian J Clin Biochem.
2009;24:52–9. PMC free article PubMed
• 22.Jayakumar RV, Nisha B, Unnikrishnan AG, Nair V, Kumar H.
Thyroidstatus in metabolic syndrome – a clinical study. Thyroid
Researchand Practice,2010;366-370.
• 23.World Health Organisation. Obesity: preventing and managing the
global epidemic. Report on a WHO Consultation on Obesity. Geneva:
WHO; 1997.
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E and Prabhakaran D, 2014. Hypertension in India: a systematic review
and meta-analysis of prevalence, awareness, and control of
hypertension. Journal of Hypertension, Vol. 32, No. 6, p. 1170
PATIENT PROFORMA

• Name: Age (in years):


• Sex:
• ANTHROPOMETRY:
• Height in meters: Weight in kg: BMI(kg/m2)
• ADDRESS:
• OCCUPATION
• HISTORY OF PRESENT ILLNESS:
• Hyperactivity +/- irritability +/-
palpitation +/- tremor +/-
• Heat intolerance +/- nervousness+/-
fatigue +/- weight loss/gain
• Hair loss +/- constipation +/- dryness
of skin +/- sleep apnea +/-
PATIENT PROFORMA

• HISTORY OF PRESENT ILLNESS:


• Hyperactivity +/- irritability +/- palpitation +/-
tremor +/-
• Heat intolerance +/- nervousness+/- fatigue +/-
weight loss/gain
• Hair loss +/- constipation +/- dryness of skin +/-
sleep apnea +/-
• HISTORY OF PAST ILLNESS:
• PERSONAL HISTORY: (including menstrual history)
PATIENT PROFORMA

• GENERAL PHYSICAL EXAMINATION:


• Pulse rate: BP:
• Pallor: Y/N Cyanosis: Y/N Icterus: Y/N Pedal
Oedema: Y/N
• Clubbing: Y/N Lymph nodes: Y/N
• Periorbital puffiness: +/- Dull expressionless: +/- large
tongue: +/-
• Thyroid enlargement: +/- protrusion of eyeball: +/-
excessive sweeting: +/-
PATIENT PROFORMA

• CNS EXAMINATION
• RESPIRATORY SYSTEM EXAMINATION:
• CVS EXAMINATION:
• ABDOMINAL EXAMINATION:
BIOCHEMICAL AND OTHER INVESTIGATION

• BIOCHEMICAL AND OTHER INVESTIGATION


• Fasting blood sugar
• Hemoglobin
• Lipid profile - Total cholesterol
• Serum triglycerides, HDL, LDL
• Thyroid profile
• Free T3
• Free T4
• TSH
• Anti-TPO
CONSENT FORM
• DEPARTMENT OF PHYSIOLOGY
• MAULANA AZAD MEDICAL COLLEGE AND ASSOCIATED L.N.
• GIPMER AND G.N.E.C. AND HOSPITALS, NEW DELHI – 110002
• CONSENT FORM
• I/ my relative, exercising my free power of choice, hereby give my/relative consent for myself to
be a subject in the
• Study titled-A CROSS SECTIONAL STUDY ON THE PREVALENCE OF TYROID
DISORDERS AMONG ADULTS IN THE URBAN POPULATION OF DELH.
• I/relative have been informed to my satisfaction, by the attending physician
• Dr. _Mohd Aslam__________________, the purpose of the study and nature of investigation to
be carried
• out.
• I/relative understand that a doctor will conduct a physical examination and other investigations
including blood tests which may be of relevance to the study.
• I/relative aware of my right to opt out of the study at any time during the course of the study
without having to give the reasons for doing so.
• I/relative have also been told that a relative/known person would accompany me to the recording
room.

• Signature of attending Physician Signature of Patient
DEPARTMENT OF PHYSIOLOGY
MAULANA AZAD MEDICAL COLLEGE
AND ASSOCIATED HOSPITALS, NEW
DELHI – 110002
• लिखित सहमति फार्म
• मैं/रिश्तेदार, अपनी मर्जी से, इस अध्ययन में एक विषय बनने के लिए अपनी/(रिश्तेदार) सहमति देता हूँ
• शीर्षक : दिल्ली के शहरी आबादी में वयस्कों में थायराइड विकारों की व्यापकता पर एक क्रॉस सेक्शनल अध्ययन I उपस्थित
चिकित्सक डॉ द्वारा मुझे/(रिश्तेदार) मेरी संतुष्टि के बारे में
• सूचित किया गया है तथा अध्ययन के बारे में बताया गया है
• मैं/(रिश्तेदार) समझता हूँ कि डॉक्टर शारीरिक परीक्षण और रक्त परीक्षण सहित अन्य जॉच करेगा जो अध्ययन के लिए प्रासंगिकता हो
सकता है।
• मैं/(रिश्तेदार) अध्ययन के दौरान किसी भी समय कारण बताए बिना अध्ययन से बाहर निकलने के अपने अधिकार से अवगत हूँ।
• मुझे/(रिश्तेदार) यह भी बताया गया है कि एक ज्ञात व्यक्ति मेरे साथ रिकॉडिंग रुम में जाएगा

• चिकित्सक हस्ताक्षर रोगी के हस्ताक्षर

• रिश्तेदार का हस्ताक्षर /रिकार्डिंग के समय मौजूद अस्पताल के कर्मचारी का हस्ताक्षर

• तारीख:
DEPARTMENT OF PHYSIOLOGY
MAULANA AZAD MEDICAL COLLEGE AND
ASSOCIATED AND HOSPITALS,
NEW DELHI – 110002
• PATIENT INFORMATION SHEET
• TITTLE: A CROSS SECTIONAL STUDY ON THE PREVALENCE
OF THYROID DISORDERS AMONG ADULTS IN THE URBAN
POPULATION OF DELHI.
• You are invited to participate in a study conducted by Dr.Mohd Aslam,
who is a student of MD in Physiology at Maulana Azad Medical
College. In this study we will assess thyroid function status, lipid
profile, anthropometry parameter and clinical examination in study
subjects. The data thus obtained would be analyzed in thyroid profile in
urban community of Delhi.
• You/relative would ask few questions related to your health, detail
history and a clinical examination would be done followed by a blood
investigation where blood sample(3ml) would be taken.
PATIENT INFORMATION SHEET

• Thyroid function test,lipid profile ,anthropometry parameter and blood


sugar examination would be done. Your cooperation is requested for these
procedures.
• There is a minimal, non-significant risk involved in blood collection. All
procedures would be done under aseptic conditions and your comfort
would be of prime importance. Your participation in the study is voluntary
and free of cost. You may choose to withdraw from the study any time
without any penalty. Your withdrawal from the study would not affect your
treatment in the institute. Your information will be kept confidential if this
study is published. No payment will be made to you to participate in our
study. If any complications occur you will not be given any compensation,
but will be treated in hospital for it.
• Your participation would be helpful in exploring relationship between the
thyroid gland function status lipid profile and anthropometry parameter,
which can be used for management of various diseases. You would also be
benefited by getting various blood investigations at free of cost.
PATIENT INFORMATION SHEET

• For any further information you/relative can contact following.


• Dr.Mohd Aslam Dr.Aartisood Mahajan,Director
professor &Hod Dept.of physiology,
• MAMAC&Associated Hospitals,New Delhi.110002
• Phone no. 9968604301
• 1st year Post graduate
• Dept.of physiolog
• MAMC& Associated Hospitals
• New Delhi-110002
• Phone no.7987911731
PATIENT INFORMATION SHEET

• Institutional Ethics Committee address, mail id & phone number



• Correspondence Address:
• Dr. Shalini Chawla (Member secretary)
• Institutional Ethics Committee
• 3rdFloor, Room No.306A.
• Maulana Azad Medical college
• Bahadur Shah Zafar Marg
• New Delhi-110002
• Contact No: 01123239271.Ext-308.

PATIENT INFORMATION SHEET
• DEPARTMENT OF PHYSIOLOGY
• MAULANA AZAD MEDICAL COLLEGE AND ASSOCIATED HOSPITALS,NEW DELHI – 110002
• रोगी सूचना पत्र
• शीर्षक : दिल्ली के शहरी आबादी में वयस्कों में थायराइड विकारों की व्यापकता पर एक क्रॉस सेक्शनल अध्ययन I
• आपको डॉ मोहम्मद असलम द्वारा अध्ययन में भाग लेने के लिए आमंत्रित किया जाता है, जो मौलना आजाद मेडिकल कालेज में फिजियोलॉजी में एमडी के छात्र हैं | इस अध्ययन में हम
थाइराईड कार्य परीक्षण,तथा रोग विषयक परीक्षण करेंगे। इस प्रकार प्राप्त आंकडौ का विश्लेषण थाइराईड कार्य में किया जायेगा। आपसे/(रिश्तेदार) अपने स्वास्थ्य से संबंधित कु छ प्रश्न
पूछे जाएंगे और एक रोग विषयक परीक्षण रक्त जांच के बाद की जाएगी जहाँ रक्त नमूना (3 एमएल) लिया जाएगा।
• थाइराइड कार्य परीक्षण, और रोग विषयक परीक्षण किया जाएगा। इस प्रक्रिया के लिये आपके सहयोग का अनुरोध किया गया है रक्त संग्रह में शामिल एक न्यूनतम, गैर महत्वपूर्ण जोखिम है।
सभी प्रक्रियाओं को निर्जिवाणुक परिस्थितियों में किया जाएगा तथा आपकी आरामदायक स्थिति महत्वपूर्ण होगी। अध्ययन में आपकी भागीदारी स्वैच्छिक और निशुल्क होगी। आप बिना किसी
दंड के किसी भी समय अध्ययन। से हटना चुन सकते है। अध्ययन से आपकी वापसी संस्थान में आपके ईलाज को प्रभावित नहीं करेगी। यदि यह अध्ययन प्रकाशित हुआ तो आपकी
जानकारी गोपनीय रखी जाएगी। इस अध्ययन में भागीदारी के लिए आपको कोई भुगतान नहीं किया जाएगा। अगर कोई परेशानी आती है तो कोई मुआवजा नहीं दिया जाएगा, लेकिन इसके
लिये आपका इलाज अस्पताल में किया जाएगा
• आपकी भागीदारी थाइराइड ग्रंथी कार्य की स्थिति व रोग विषयक परीक्षण के बीच सम्बंधो की खोज में सहायक होगी, जिसका उपयोग विभिन्न रोगों के प्रबंधन के लिये किया जा सकता है।
• आप विभिन्न रक्त जांच को मुक्त परीक्षण करके लाभान्वित होगें।

• किसी और जानकारी के लिये आप निम्नलिखित से संपर्क कर सकते हैं।
• डॉ मोहम्मद असलम डॉ आरती सूद माहाजन
• प्रथम वर्ष स्नातकोंतर निदेशक प्राध्यापक
• फिजियोलॉजी विभाग शरीर क्रिया विज्ञान
• एमएएमसी और संबंधित अस्पताल, एमएएमसी और संबंधित अस्पताल
• नई दिल्ली -110002 नई दिल्ली -110002
• फोन नंबर7987911731 फोन नंबर 9968604301

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• संस्थागत निति आयोग का पता, मेल आईडी, फोन नंबर
• लिखा पढी का पता
• डॉ प्रोफे सर शालिनी चावला (सदस्य सचिव)
• संस्थागत निति आयोग
• 3 मंजिल कमरा नम्बर 306A,
• मौलाना आजाद मेडिकल कॉलेज
• बहादुर शाह जाफर मार्ग
• नई दिल्ली -11002
• सम्पर्क नम्बर: 01123239271,Ext-380.

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