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WOMEN‘S HEALTH
Lisnadiyanti
Dysfunctional Uterine Bleeding
DUB : Abnormally Heavy, light or irregular
bleeding
Most problems are related to endocrine
disruptions that alter normal cyclic changes
in endometrium
DUB also may due to organic disease, such
as neoplasms and infections
DUB can be chronic problem contributing to
iron deficiency anemia
Continu…..
Dysfunctional uterine bleeding (DUB) is defined
as abnormal uterine bleeding in the absence of
organic disease.
Dysfunctional uterine bleeding is the most
common cause of abnormal vaginal bleeding
during a woman's reproductive years.
Dysfunctional uterine bleeding can have a
substantial financial and quality-of-life burden.
It affects women's health both medically and
socially.
Dysfunctional Uterine Bleeding (DUB)
It is an abnormal bleeding from the uterus in the
absence of organic disease of the genital tract.
It is characterized by dysfunction of the uterus,
ovary, pituitary, hypothalamus or other part of
reproductive system.
the pattern of bleeding is mainly heavy &
regular ( menorrhagia ) but it could be irregular
uterine bleeding or intermenstrual bleeding.
Continue….
Introduction
•Dysfunctional uterine bleeding (DUB) is defined
as ABNORMAL uterine bleeding with no demonstrable
organic cause, genital or extragenital.
•Patients present with “abnormal uterine bleeding”
( amenorrhea )
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Physiology
Contunue…..
Normal Menstruation
Estradiol and progesterone levels decrease several
days prior to the onset of menses.
Endometrial blood flow decreases
Endometrial height decreases and vascular stasis occurs.
Tissue ischemia occurs.
Arterial relaxation
Sloughing of the endometrium.
Uterine bleeding occurs
Anovulasi
Failure of the ovaries to release or
produce mature eggs
Causes about 90% of DUB
Common causes :
1. Pituitary adenoma
2. Polycystic ovarium syndrome
3. Contraceptives
4. Endometrial infections
5. Cervicitis
Hypomenorrhea
Short, scant menstrual flow, may result
from endocrine dysfunction]
Menstrual flow may be light or consist only
of spotting for 1 to 2 days
Short cycles ( 17 – 20 days )
Women younger than 30 years with
consistent are more prone to infertility and
increased risk for endometrial carcinoma
Oral contraceptives and cervical stenosis
can lead to Hypomenorrhea
Common causes of DUB
Endometriosis
The normal tissue lining the uterine cavity is called the
endometrium.
Endometriosis is a condition in which the presence
of this endometrial tissue moves outside the uterus.
The most common places for implantation are the
ovaries, fallopian tubes, bladder and intestines, uterine
wall, and the lining of the pelvis.
Medical treatment : oral contraceptives to suppress
estrogen production and tinning the endometrial lining,
Danazol and nafarelin
Endometriosis image
Endometriosis image
The symptoms of endometriosis
Painful periods (dysmenorrhea)
This pain can vary. It may start just prior to menstruation or
even several days before menstruation begins. The pain is
generally at its worst during the point of heaviest flow.
Frequently, large clots are seen. Pain can also be present in
other locations during the period
Pain During Intercourse (Dyspareunia)
This usually results from tissue implants deep in the pelvic wall
that have infiltrated the lining of the abdomen (peritoneum),
and from adhesion (scar tissue) formation.
Pelvic Pain
This usually results from a collection of shed (regurgitated)
menstrual blood in the abdominal cavity causing local
abdominal (peritoneal) inflammation. Pelvic pain can be very
similar to that of appendicitis; patients complain of pain in the
lower right region of their abdomens.
Back pain
Intermenstrual Bleeding
Intermenstrrual bleeding is vaginal bleeding (other than post-coital) at
any time during the menstrual cycle other than during normal menstruation.
Bleeding between periods (intermenstrrual bleeding) may be associated with
sexual intercourse - bleeding during intercourse
Bleeding between periods may be in the middle of the menstrual cycle - mid
cycle bleeding or mid cycle spotting.
Women on the pill may experience break through bleeding.
This is not strictly intermenstrual bleeding because the monthly bleeding
experienced by those women taking the pill is correctly called 'withdrawal
bleeding' and is not spontaneous menstruation.
Intermenstrual bleeding may amount to no more than spotting between
periods or it may be heavy.
Cervical polyps
Cervical erosion - ectropion
Cervicitis (most commonly causes blood-tinged discharge)
Condylomata acuminata of the cervix
Cancer (but bleeding is most often post-coital)
What causes intermenstrual bleeding?
4. Uterine causes:
Endometrial polyps
Fibroids
Adenomyosis (usually only symptomatic in later reproductive
years)
Endometrial adenocarcinoma
5. Oestrogen-secreting ovarian cancers
Clinical Assessment
A reproductive history should always be obtained,
including the following: Age of menarche and menstrual
history and regularity
Last menstrual period (LMP), including flow, duration,
and presence of dysmenorrhea
Postcoital bleeding
Gravida and para
Previous abortion or recent termination of pregnancy
Contraceptive use, use of barrier protection, and
sexual activity (including vigorous sexual activity
or trauma)
History of sexually transmitted diseases (STDs)
or ectopic pregnancy
Treatment of DUB
Goals
control bleeding
prevent recurrence
preserve fertility
correct associated conditions
induce ovulation in patients who want to
conceive
Nursing Assessment
Menstrual History :