A peripheral blood smear was taken from a patient with fever, chills, and rigors and found crescent-shaped gametocytes of Plasmodium falciparum under the microscope. P. falciparum has an incubation period of 12 days on average between a mosquito bite and symptoms appearing. It is transmitted to humans by the female Anopheles mosquito. Recent developments in malaria diagnosis and prophylaxis include fluorescence microscopy, rapid antigen detection tests, molecular detection methods like PCR, and vaccine research though an effective vaccine is still not available.
A peripheral blood smear was taken from a patient with fever, chills, and rigors and found crescent-shaped gametocytes of Plasmodium falciparum under the microscope. P. falciparum has an incubation period of 12 days on average between a mosquito bite and symptoms appearing. It is transmitted to humans by the female Anopheles mosquito. Recent developments in malaria diagnosis and prophylaxis include fluorescence microscopy, rapid antigen detection tests, molecular detection methods like PCR, and vaccine research though an effective vaccine is still not available.
A peripheral blood smear was taken from a patient with fever, chills, and rigors and found crescent-shaped gametocytes of Plasmodium falciparum under the microscope. P. falciparum has an incubation period of 12 days on average between a mosquito bite and symptoms appearing. It is transmitted to humans by the female Anopheles mosquito. Recent developments in malaria diagnosis and prophylaxis include fluorescence microscopy, rapid antigen detection tests, molecular detection methods like PCR, and vaccine research though an effective vaccine is still not available.
• Describe what you have seen under microscope and identify the parasite and name the species. • Crescent shape gametocytes of P. falciparum
• What is the incubation period of these parasites?
• Interval between the infective mosquito bite and the first appearance of clinical symptoms; varies with the species of the parasite. – P. vivax—14 (8–31) days – P. falciparum—12 (8–14) days – P. ovale—14 (8–31) days – P. malariae—28 (18–40) days • Which mosquito transmits the parasite to man? • Female Anopheles mosquito
• What are the recent developments in this field?
• Diagnosis – Fluoroscence microscopy (acridine orange) – Immunochromatographic tests for rapid antigen detection – Molecular methods- DNA probes and PCR • Prophylaxis – Though, effective vaccine is not yet available for malaria, several vaccines are under development