‫امارت اسالمی افغانستان‬

‫وزارت صحت عامه‬

‫شفاخانه تخصصی پروان‬
‫دیپارتمنت داخله عمومی‬
‫دیابت بی مزه‬

‫تهیه و ترتیب ‪ :‬ناصر ارمان‬

Contains
• Definition
• Types
• Causes
• Clinical manifestations
• Laboratory studies
• Deffrentiation diagnosis
• Treatment
Deffination

• Diabetes insipidus is a rare condition where you pee a lot and often
feel thirsty.
Types
• Cranial
• Nephrogenic
Cranial DI
• Primary DI
• Secondary DI
• Vasopressinase induced DI
• Tumors
• Surgery
• Trauma
• Radiation
• Infections
• Idiopathic
• Gestational DI
Nephrogenic DI
• V2 Receptors insufficiency
• Pyelonphritis
• Renal Amyloidosis
• Sickle cell anemia
• Chronic hypercalcemia
• Multipal Myeloma
• Drugs
Clinical manifestations
• Pollyurea
• Pollydepsia
• General Clinical manifestations
Laboratory Studies
• Testing urine to see if it contains too much water can be helpful in
identifying diabetes insipidus. Blood tests. Checking the levels of
certain substances in the blood, such as sodium, potassium and
calcium, can help with a diagnosis and may be useful in identifying the
type of diabetes insipidus
Differential diagnosis
• DM type 2
• Drug induced pollyurea
Treatment of cranial DI
• Desmopressin
• Lepressin
• Chlorpropamid
• Carbamazepin
Treatment of Nephrogenic DI
• Hydrochlorothiazide + Desmopressin
• Hydrochlorothiazide + Indomethacin
• Thanks