membranes Fetal membranes continues • Fetal membranes consist of two layers ie • The chorion • The amnion The chorion • This is the outer layer of the two fetal membranes • It's thicker than the amnion, friable and shaggy on both sides . • Internally, it's attached to the amnion by loose areolar tissue and remnant of primitive mesenchyme • Externally it's covered by vestiges of trophoblastic layer and decidual cells of the fused decidua capsularis and parietalis. Amnion • It's the inner layer of the fetal membranes • Internal surface is smooth and shiny and is in contact with amniotic fluid. • A fully formed amnion is 0.02-0.5mm in thickness. Functions of fetal membranes . Intact membranes prevent ascending uterine infections . Facilitates dilation of the cervix during labor . Has got enzyme activities for steroid hormonal metabolism .They are rich source of glycerophospholipids containing arachidonic acid which is a precursor of prostaglandin E2 and F2 alpha . Contributes to the formation of liquor amnii Clinical correlates • Prelabor rupture of membranes (PROM) • Preterm prelabor rupture of membranes (PPROM) • Chorioamnionitis