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9.

Miscellaneous Diseases

( Infertility )
Section 1. Infertility
与分析
1.1 Etiology & Pathogenesis

1.2 Diagnosis & Differential Diagnosis

1.3 Pattern Differentiation and


Treatments

1.4 Acupuncture and Moxibustion


Treatment
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Section 1. Infertility 与分析
1.5 Chinese Patent Medicines

1.6 Prognosis

1.7 Prevention and Self-Care

1.8 Case Study

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Section 1. Infertility 与分析

Infertility (不孕症, Bu Yun Zheng


) is defined as no conception after one
year of active sex , without the use of
contraceptives .

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If a woman has never become
pregnant , it is referred to as primary
infertility . If there has been a
pregnancy in the past ( including full
term pregnancy , miscarriage , ectopic
or molar pregnancy ) but attempts for
another pregnancy fail after one year
of trying , it is referred to as secondary
infertility .

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Section 1. Infertility 与分析

The causes of infertility are associated


with both the man and the woman . In
this chapter we consider female
fertility only .

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Section 1. Infertility 分析
1.1 Etiology & Pathogenesis

Infertility is mainly related to kidney


deficiency and qi - blood disorder in
chong mai and ren mai . The more
common clinical patterns are : a
deficiency of kidney - qi , liver
stagnation , phlegm dampness and
blood stasis .
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Kidney deficiency ? What can cause 集

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liver constraint ?
What can cause 集

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blood stasis ?
What can cause 集

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phlegm dampness ? What can cause 集

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Differential Diagnosis 集与分析

be distinguished from case history

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The physician should inquire about the
woman’s age, health status, sexual life
and how long she has been trying to
conceive. Information about
menstruation , previous pregnancy
and delivery , abortions or
miscarriages is important .
Differential Diagnosis

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He or she should also pay close
attention to whether or not there is any
history of pelvic infection , what
contraception method has been used in
the past and if there have been
abdominal ( or other ) surgeries in the
past . Any previous or present
endocrinopathy or tuberculosis is
relevant .
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Family history might include inherited
diseases , heart disease , diabetes , high
blood pressure , high cholesterol or
mental issues .

Differential Diagnosis

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Differential Diagnosis 集与分析

should be distinguished from


Symptoms

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Different causes of infertility present with
different symptoms .
In the case of ovulatory dysfunction ,
menstrual disorders may be reported
including, amenorrhea . In the case of
endometriosis , infertility is often
accompanied by dysmenorrhea or
spotting before the period .

Differential Diagnosis
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In the case of salpingitis , there may be
pain in the lower abdomen and excessive
vaginal discharge . A woman with uterine
adhesions may also have scanty or no
periods . In the case of immune
infertility , there may be no obvious
symptoms .

Differential Diagnosis
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Essentials of Pattern Differentiation 集与分

Differentiation of
patterns
While the main concern is inability to conceive ,
details of menstrual and gynecological history as
well as general health are relevant .
 Delayed menarche , a consistently late
menstrual cycle with scanty flow , accompanied
by soreness of the waist and weak legs , are
symptoms of a kidney deficiency pattern .
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Essentials of Pattern Differentiation 集与分

If there is an irregular menstrual cycle ,


unsmooth menstrual flow , accompanied by a
distending pain in the breasts and
hypochondrium , and disturbed emotions , it is
mostly caused by liver constraint .
 If there is obesity , it indicates phlegm
dampness .
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Essentials of Pattern Differentiation 集与分

 If there is pain in the lower abdomen with
scanty menstruation , it belongs to the pattern
of blood stasis .

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Treatment Principles 集与分析

 The emphasis of treatment is on


warming and nourishing the kidney - qi and
regulating qi and blood and keeping the
menstrual cycle regular . Conception is
then more likely to occur .

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Treatment Principles 集与分析

 The patient needs to have balanced emotions


and circumstances , to be temperate in sexual
activity , and to be aware of her optimum fertile
period at ovulation as the ideal time for intercourse
and conception .

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Pattern Differentiation and Treatments 集
与分析
Infertility
1.Kidney deficiency
1.1 Kidney-qi deficiency
[ Main Manifestations ]

Long term infertility , irregular


menstruation , menstrual volume
sometimes being excessive or sometimes
scanty .
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Pattern Differentiation and Treatments 集
Infertility
与分析
1.Kidney deficiency
1.1 Kidney-qi deficiency
[ Other Signs and Symptoms ]

 Dizziness and tinnitus , soreness of the


waist and weakness of the legs , clear long
urine , fatigue and low spirits .
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Pattern Differentiation and Treatments 集
Infertility
与分析
1.Kidney deficiency
1.1 Kidney-qi deficiency
 [ Tongue and Pulse ]

A pale tongue with a thin coating ,


and a deep and thready pulse ,
especially in both chi regions.
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[ Treatment Principles ]
Tonify the kidney and boost qi ,
reinforce the essence and supplement
bone marrow .
[ Formula ]

 Yu Lin Zhu ( Unicorn - Rearing Pill , 毓


麟珠) .
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Pattern Differentiation and Treatments 集
与分析
Infertility
1.Kidney deficiency
1.2 Kidney-yang deficiency
[ Main Manifestations ]

Long term infertility , late scanty


pale periods or amenorrhea ,
excessive vaginal discharge .

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Pattern Differentiation and Treatments 集
Infertility
与分析
1.Kidney deficiency
1.2 Kidney-yang deficiency
[ Other Signs and Symptoms ]

A cold abdomen and limbs , low sexual


desire , frequent urination or incontinence ,
dark and dull complexion .

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Pattern Differentiation and Treatments 集
与分析
Infertility
1.Kidney deficiency
1.2 Kidney-yang deficiency
 [ Tongue and Pulse ]

A pale tongue with a white , moist


coating , and a deep , slow , thready or
weak pulse .
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[ Treatment Principles ]

Warm the kidney and assist yang ,


dissolve dampness and consolidate
essence .

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[ Formula ]

Wen Bao Yin ( Uterus - Warming


Decoction , 温胞饮) .

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Pattern Differentiation and Treatments 集
与分析
Infertility
1.Kidney deficiency
1.3 Kidney-yin deficiency
[ Main Manifestations ]

Long term infertility , delayed , scanty and


light red menstrual periods .

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Pattern Differentiation and Treatments 集
与分析
Infertility
1.Kidney deficiency
1.3 Kidney-yin deficiency
[ Other Signs and Symptoms ]

Dizziness and tinnitus , soreness of the waist


and weakness of the legs , blurred vision ,
palpitations , sallow , yellowish complexion .
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Pattern Differentiation and Treatments 集
与分析
Infertility
1.Kidney deficiency
1.3 Kidney-yin deficiency
[ Tongue and Pulse ]

 A pale tongue with a thin coating ,


and a deep , thready pulse .

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[ Treatment Principles ]

nourish the kidney and the blood,


regulate and tonify chong mai and ren
mai.

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[ Formula ]

Yang Jing Zhong Yu Tang (养精种玉


汤, Essence - Nourishing Jade -
Planting Decoction ).

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Pattern Differentiation and Treatments 集
与分析
Infertility
2. Liver constraint
[ Main Manifestations ]

 Infertility for more than a year ,


delayed menstrual cycle , variable
menstrual volume , breast distention
premenstrually .
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Pattern Differentiation and Treatments 集
Infertility
与分析
2. Liver constraint
[ Other Signs and Symptoms ]

 Discomfort in the chest and


hypochondrium , distending pain in the lower
abdomen , emotional depression or restlessness
and irritability .
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Pattern Differentiation and Treatments 集
与分析
Infertility
2. Liver constraint
[ Tongue and Pulse ]

A red tongue with a thin coating , and a wiry


pulse .

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Infertility
2. Liver constraint
[ Treatment Principles ]
Soothe the liver and relieve
constraint , and regulate the blood and
menstruation .
[ Formula ]

Kai Yu Zhong Yu Tang (开郁种玉汤,


Depression - Opening Jade - Planting
Decoction )
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Pattern Differentiation and Treatments 集
与分析
Infertility
3. Phlegm - damp
[ Main Manifestations ]

 Infertility for a long time , obesity ,


delayed menstrual cycle or amenorrhea ,
excessive vaginal discharge , whitish in
color and sticky in nature without odor .
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Pattern Differentiation and Treatments 集
Infertility
与分析
3. Phlegm - damp
[ Other Signs and Symptoms ]

 Dizziness and palpitations , chest distress


and nausea , bright white complexion .

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Pattern Differentiation and Treatments 集
与分析
Infertility
3. Phlegm - damp
[ Tongue and Pulse ]

A tongue with a white greasy coating , and a


slippery pulse .

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Infertility
3. Phlegm - damp
[ Treatment Principles ]
Dry the dampness and dissolve the
phlegm , regulate qi and
menstruation .
[ Formula ]

 Qi Gong Wan (启宫丸, Uterus -


Opening Pill ).

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Pattern Differentiation and Treatments 集
与分析
Infertility
4. Blood stasis
[ Main Manifestations ]

 Infertility for many years , a delayed


menstrual cycle , variable menstrual
volume , dark purple in color , unsmooth
flow with blood clots .
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Pattern Differentiation and Treatments 集
Infertility
与分析
4. Blood stasis
[ Other Signs and Symptoms ]

 Pain in the lower abdomen aggravated


with pressure , increasing before and during
menstruation .

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Pattern Differentiation and Treatments 集
与分析
Infertility
4. Blood stasis
[ Tongue and Pulse ]

A dark purple tongue , or a tongue with


petechiae at the edge of the tongue , and a
wiry and choppy pulse.

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Infertility
4. Blood stasis
[ Treatment Principles ]
Invigorate the blood and dissolve stasis
, warm the vessels and unblock the
collaterals .
[ Formula ]

 Shao Fu Zhu Yu Tang (少腹逐瘀汤,


Lesser Abdomen Stasis - Expelling
Decoction )
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[ CASE STUDY ]

Ms . Zhai , age 28, a nurse .

Chief Complaint : Inability to conceive


for three years , with regular sexual
activity and no contraceptive use .

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[ CASE STUDY ]

History of Present Illness: The patient


had been married for three years , with
a normal sexual life , not using any
form of contraception ; but she was
unable to conceive .

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[ CASE STUDY ]

History of Present Illness: Her body


weight gradually increased . Her
menstruation lasted for 3-4 days with a
32-37 day cycle . The menses were
scanty with no dysmenorrhea . There
was also slight leakage of breast milk .
Previous examination at another
hospital revealed increased prolactin in
the blood . Other hormone levels were
normal .
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[ CASE STUDY ]

History of Present Illness: Previous


intermittent treatment with
bromocriptine showed no significant
effects . After adding metformin ,
breast milk leakage was reduced , but
so was menstrual flow . The menses
were red and slightly pale . At the first
visit , the patient ' s menstruation had
been absent for two months .
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[ CASE STUDY ]

History of Present Illness: There was


no abdominal pain or other
discomfort . The patient was obese with
a flushed complexion . The tongue was
pale with a white greasy coating , and
her pulses were thready and slippery .

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[ CASE STUDY ]

Histories of menstruation , leucorrhea ,


pregnancy and delivery:
Her menarche occurred at age 14,
lasting for 3-4 days , with a cycle of 32-
37 days , and a scanty volume .

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[ CASE STUDY ]

Past History:
She was healthy in the past with no
special disease history .

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[ CASE STUDY ]

Gynecological Examination:
The vulva and vagina were normal ,
with moderate , light yellow vaginal
discharge. The cervix was smooth and
glossy . The uterus was anteverted , of
normal size , good mobility and no
tenderness . There was no tenderness in
both adnexa . No obvious mass was
palpated .
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[ CASE STUDY ]

TCM Diagnosis

① Infertility due to internal


obstruction of phlegm - dampness . ②
Delayed menstrual cycle due to
obstruction of phlegm - dampness .
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[ CASE STUDY ]
Pattern Differentiation
The patient has an improper diet , which
impairs the function of the spleen and the
stomach . Spleen deficiency leads to a
failure in transportation , which gives rise to
retention of water dampness . The collected
dampness transforms into phlegm and
obstructs qi movement , leading to qi
stagnation and blood stasis .
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[ CASE STUDY ]
Pattern Differentiation
Phlegm binds with stasis to obstruct the
chong and ren mai , resulting in infertility .
The obstruction of the chong and ren mai
leads to delayed menstruation or
amenorrhea . The pale tongue with a white
greasy coating , and thready slippery pulses
are signs of spleen deficiency with phlegm
obstruction .
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[ CASE STUDY ]

Treatment Principles

Invigorate the spleen and tonify the


kidney , dry the dampness and resolve the
phlegm , and invigorate the blood and
regulate menstruation .
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[ CASE STUDY ]

Formula

 Modified Qi Gong Wan (启宫丸,


Uterus - Opening Pill )

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