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Ethics
BY
In one of the most highly publicized cases of alleged scientific misconduct in recent
memory, which has become known as the “Baltimore Affair,” a paper co-authored by
Nobel Prize winning scientist David Baltimore was suspected of containing fraudulent
data. During the Summer of 1991, the New York Times gave this story front page
coverage. This scandal embarrassed the organizations that sponsored the research,
including the National Institute of Health (NIH) and the Whitehead Institute, tarnished
Baltimore’s reputation, attracted the attention of Congress, and even involved the Secret
Service. The paper, which appeared in the 25 April 1986 issue of the journal Cell, listed
six authors. Baltimore supervised the research, although he did not perform the
experiments. The paper experiments showed that the insertion of a foreign gene into a
mouse can induce the mouse’s genes to produce antibodies mimicking those of the
foreign gene. If this claim were true, it would suggest that one could control the immune
system by using foreign genes to make it produce antibodies. So far, this research has not
been confirmed by other scientists.
She begins a search for the old data used to write this paper and
to her surprise she finds that the records do not agree with the
results the professor reported in the paper. It appears as if Jonas
omitted about 10 percent of the recorded data. Akua talks to
Jonas about this discrepancy and he explains that he omitted
some of the data because he felt the telescope was not working
correctly when it produced these poor results. She presses him
further on this issue and he tells her to trust his judgment.
Questions:
Should they submit a correction to the journal?
What should Butamo do if his colleagues do not want to submit a
correction?
Crime does not pay in science, because the scientific method, the
peer review system, and the public nature of scientific research
serve as mechanisms for catching people who break science’s
ethical rules.