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The Fantastic Voyage

Research 2- The Cell Cycle


CompiledbyEmilyClarkson

Duplicating Cells
Everycellhasits6me;itgrows,works,eventuallyitwearsoutanddies.Tokeepthebalanceofan organism,dyingcellsarereplacedthroughadividingprocessknownasMitosis.Howeverbefore mitosiscanoccur,anumberofchangesmusttakeplaceinacellbeforeitcansplitintotwo iden6calones.Thelifecycleofacellcanbeseeninthediagrambelow.

The Cell Cycle- Interphase


ThecyclebeginsonthisdiagramatG1.G1isaperiodofgrowthinthecell,maturingand increasinginsize.FollowingthiscomestheSPhase(DNASynthesis).Thecellcreatesanexact copyofallthechromosomesofDNAinthenucleus.AJerthiscomesasecondaryperiodofgrowth G2.ThesethreephasesG1SPhaseandG2allcomeundertheMitosisperiodnamed InterphaseItmakesupthemajorityofacellslife.Thenextfewstagesseethecellac6vely duplicatetoformadaughtercell.

The Cell Cycle- Prophase


ThebeginningoftheMstageofthecycle(otherwiseknownasMitosis)isknownasProphase. HeretheDNAchromosomescoilandcondense,sotheycanbeclearlyseenunderamicroscope. TheyappearxshapedandareknownasChroma6ds(seenmoreclearlyontheillustra6oninthe nextstage)Thechroma6dscompriseofapairofiden6calchromosomes,producedinthe synthesisstage.Atthis6methenucleolus(thedensepartofthenucleus)disappears.The organellesknownascentriolesbegintomigrate,sothatoneislocatedoppositetheother,atpole endsofthecell.

Nucleus

DNA

Centrioles

The Cell Cycle- Metaphase


FollowingProphasecomestheMetaphase.Atthisstagetheen6renuclearmembranebreaks downtoallowthechroma6dstolineupinthecentreofthecell.Thebreakingdownofthenuclear membranealsogiveswaytothespindles.Thespindlesare6nymicrotubules,producedbythe centrioles,nowateitherendofthecell.Thosespindleslatchontothecentresofthechroma6ds, eachchroma6disheldbyonespindlefromeachcentriole.Readyforthenextstagecalled Anaphase.

Chroma6d Spindle Centriole

The Cell Cycle- Anaphase


Anaphaseistheperiodinwhichthecentriolespullawayfromeachother,theirspindlespulling andbreakingthechroma6dsintwo.Eachhalfisnowtechnicallyonechromosome,theybare iden6calgene6cinforma6on.Thecentriolespullthetwoiden6calpairsawayfromeachotherto oppositeendsofthesamecellreadyforthenalpartofthedivisionintotwoiden6calcells.

SisterChroma6ds

Chromosome Spindle Centriole

The Cell Cycle- Telophase


Telophaseisthenalstep.Thetwocompletesetsofgene6cinforma6onhavenucleus membranesformaroundthem.Laterthosechromosomesunravelagainsotheycannolongerbe seenunderamicroscope.Thecytoplasmcon6nuestodivideun6lafullcellisformed,resul6ngin apairofiden6calcells,onemotherandonedaughter.Fromherethecyclebeginsagainandthe cellsbegintogrowbackattheG1stage

DNA Nucleus Centriole

Cytoplasm

Bibliography
Illustra6ons CellCycle hTp://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/cells2.html hTp://dedunn.edublogs.org/2011/06/08/cellcycle/ hTp://ms6boldo.blogspot.co.uk/2008/05/mytosisoryourtosis.html Variousinforma6on Overviewofcellcycle hTp://www.youtube.com/watch?v=2aVnN4RePyI hTp://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/cells2.html hTp://ms6boldo.blogspot.co.uk/2008/05/mytosisoryourtosis.html

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