Name of the Drug AMLODIPINE BESYLATE

General Action

Specific Action

Indication Angina pectoris due to coronary artery spasm (Prinzmetals variant angina) Chronic stable angina, alone or in combination with other drugs Essential hypertension, alone or in combination with other antihypertensives

Contraindications

Adverse Reaction

Nursing Responsibilities

Antianginal Inhibits the movement Antihyperte of calcium ions across the membranes of nsive cardiac and arterial Calcium muscle cells; inhibits channel Norvasc transmembrane blocker calcium flow, which Dosage: 1 tab results in the 10mg OD depression of impulse formation in specialized cardiac pacemaker cells, Pregnancy slowing of the category C velocity of conduction of the cardiac impulse, depression of myocardial contractility, and dilation of coronary arteries and arterioles and peripheral arterioles; these effects lead to decreased cardiac work, decreased cardiac oxygen consumption, and in patients with vasospatic angina, increased delivery of oxygen to cardiac cells.

Contraindicated with allergy to CNS: Dizziness, ASSESMENT: amlodipine, impaired lightheadedness, headache, History: Allergy to amlodipine, impaired hepatic or renal hepatic or renal asthenia, fatigue, lethargy function, sick sinus syndrome, heart block, lactation, heart function, sick sinus failure, syndrome, heart Physical: Skin lesions, color, edema; P, BP, baseline ECG; CV: Peripheral edema, block (second or peripheral perfusion, auscultation; R, adventitious sounds; arrhymias third degree), and liver evaluation, GI normal output; LFTs, renal function lactation. tests, urinalysis Dermatologic: Flushing, Use cautiously withrash jaundice (yellowing of INTERVENTIONS: the skin or eyes). heart failure, pregnancy. Warning: Monitor patient carefully (BP, cardiac rhythm, and GI: Nausea, abdominal output) while adjusting drug to therapeutic dose; use special discomfort caution if patient has heart failure. Urinating more or less than Monitor BP carefully if patient is also on nitrates. Monitor cardiac rhythm regularly during stabilization of usual, or not at all; dosage and periodically during long term therapy. Administer drug without regard to meals. Fever, chills, body aches, flu symptoms; Always remember and follow the 10 Rs of drug administration. Tired feeling, muscle weakness, and pounding or TEACHING POINTS: uneven heartbeats; Take with meals if upset stomach occurs. You may experienced these side effects: Nausea, vomiting chest pain; (eat frequent small meals); headache (adjust lightning, noise, and temperature; medication may ordered) swelling, rapid weight gain; Report irregular heartbeat, shortness of breath, swelling of the hands or feet, pronounced dizziness, constipation. Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking amlodipine and benazepril. Drink 6 to 8 full glasses of water daily while you are taking this medication.

Name of the Drug MEFENAMIC ACID ApoMefenamic, ponstel 500 mg 1 cap 3x/day Pregnancy category C

General Action NSAID

Specific Action

Indication

Contraindications

Adverse Reaction

Nursing Responsibilities

CNS: Headache, dizziness, BEFORE: AntiRelief of moderateContraindicated somnolence, insomnia, inflammatory, pain when therapy with Assess for history of allergies, renal, hepatic, CV,GI analgesic and will not exceed 1 hypersensitivity to fatigue, tiredness, tinnitus, conditions; pregnancy; lactation mefenamic acid, ophthalmic effects antipyretic week. Assess the physical for skin color and lesions; orientation, aspirin allergy, and Dermatologic: Rash, activities related Treatment of reflexes, opthalmolgic, and andiometric evaluation, as treatment of prurotus, sweating, dry to inhibition of primary peripheral sensation; P, edema R, adventitious sounds,; renal preoperative pain mucous prostaglandin dysmenorrhea. function tests, serum electrolytes, stool guaiac with coronary artery membranes,stomatitis synthesis; exact bypass grafting. mechanisms of DURING: GI: nausea, dyspepsia, GI action are not Be aware that patient may be at increase risk for CV events, Use cautiously with pain, diarrhea, vomiting, known. GI bleeding, monitor accordingly. asthma, renal or constipation, flatulence Give the milk or food to decrease GI upset. hepatic impairment, Arrange for periodic ophthalmologic examinations during peptic ulcer disease, GU: Dysuria, renal long-term therapy. GI bleeding, impairment If overdose occurs, institute emergence procedureshypertension heart supportive therapy and induced emesis, activated charcoal, failure, pregnancy Hematologic: bleeding, and/or an osmotic cathartic lactation. platelet inhibition wiyh Do not exceed 1 week therapy higher doses, neutropenia, Always remember and practice the 10 Rs eosinophilia, leukopenia, pancytopenia, AFTER: thrombocytopenia, Take drug with food; take only the prescribed dosage and agranulocytosis, teach not to take the drug longer than 1 week granulocytopenia, aplastic Discontinue drug and consult health care provider if rash, anemia, decrease Hgb or Hct, diarrhea, or digestive problems occur. bone marrow depression, Dizziness or drowsiness can occur ( so avoid driving and menorrhagia using dangerous machinery ) Respiratory: Dyspnea, Report sore throat, fever, rash, itching, weight gain, swelling hemoptysis, pharyngitis, in the ankles or fingers, changes in vision; cephalexin. bronchospasm, rhinitis Other: Peripheral edema, anaphylactoid reactions to anaphylactic shock