Drug Information Bulletin

Drug Information Centre (DIC) Indian Pharmaceutical Association

Bengal Branch Tele fax: 033 24612776, E-mail: ipabengal.dic@gmail.com Web Site: http://www.ipabengal.org Contact: 09830136291

th

Year

Volume: 05

Number: 51

31st March 2012

Content World TB Day celebration 2012: Stopping TB in my life time World Tuberculosis Day Themes Key facts on TB Multidrug-resistant tuberculosis-Q&A The Stop TB Strategy Pharmacist is now an active partner in TB care and control Forthcoming Event

World TB Day celebration 2012: Stopping TB in my life time

2 World Tuberculosis Day Themes Year World Theme World Theme World Theme World Theme World Theme World Theme World Theme World Theme World Theme World Theme World Theme World Theme World Theme Tuberculosis Day 2012 World Tuberculosis Day Theme "Stopping TB in My Lifetime."

Tuberculosis Day 2011 "On the move against TB: Transforming the fight towards elimination" Tuberculosis Day 2010 "On the move against TB: Innovate towards action" Tuberculosis Day 2009 Tuberculosis Day 2008 Tuberculosis Day 2007 Tuberculosis Day 2006 Tuberculosis Day 2005 Tuberculosis Day 2004 Tuberculosis Day 2003 Tuberculosis Day 2002 Tuberculosis Day 2001 Tuberculosis Day 2000 "I am stopping TB" "I am stopping TB" "TB anywhere is TB everywhere" "Actions for life Towards a world free of TB" "Frontline TB care providers: Heroes in the fight against TB" "Every breath counts Stop TB now!" "DOTS cured me it will cure you too!" "Stop TB, fight poverty" "DOTS: TB cure for all" "Forging new partnerships to Stop TB"

Key facts on TB Tuberculosis (TB) is second only to HIV/AIDS as the greatest killer worldwide due to a single infectious agent. In 2010, 8.8 million people fell ill with TB and 1.4 million died from TB. Over 95% of TB deaths occur in lowand middle-income countries, and it is among the top three causes of death for women aged 15 to 44. In 2009, there were about 10 million orphan children as a result of TB deaths among parents. TB is a leading killer of people living with HIV causing one quarter of all deaths.

Multi-drug resistant TB (MDR-TB) is present in virtually all countries surveyed. The estimated number of people falling ill with tuberculosis each year is declining, although very slowly, which means that the world is on track to achieve the Millennium Development Goal to reverse the spread of TB by 2015. The TB death rate dropped 40% between 1990 and 2010.

Multidrug-resistant tuberculosis-Q&A Q: What is multidrug-resistant tuberculosis and how do we control it?

3 A: The bacteria that cause tuberculosis (TB) can develop resistance to the antimicrobial drugs used to cure the disease. Multidrug-resistant tuberculosis (MDR-TB) is TB that does not respond to at least isoniazid and rifampicin, the two most powerful antituberculosis drugs. Every year, more MDR-TB cases are being reported. The primary cause of multidrug resistance is mismanagement of TB treatment. Most people with tuberculosis are cured by a strictly followed, six-month drug regimen that is provided to patients with support and supervision. Inappropriate or incorrect use of antimicrobial drugs, or use of ineffective formulations of drugs, can cause drug resistance. Strong and enforced regulations to ensure acceptable, effective tuberculosis treatment can help control MDR-TB. In some countries, it is becoming increasingly difficult to treat MDR-TB. Treatment options are limited and recommended medicines are not always available. In some cases even more drugresistant tuberculosis is developing. Extensively drug-resistant TB, XDR-TB, is a form of multi-drug resistant tuberculosis that responds to even fewer available medicines. There were about 650 000 cases of MDRTB present in the world in 2010. It is estimated that about 9% of these cases were XDR-TB. The Stop TB Strategy Vision, goal, objectives and targets Vision A TB-FREE WORLD Goal To dramatically reduce the global burden of TB by 2015 in line with the Millennium Development Goals and the Stop TB Partnership targets Objectives Achieve universal access to high-quality care for all people with TB Reduce the human suffering and socioeconomic burden associated with TB Protect vulnerable populations from TB, TB/HIV and multidrug-resistant TB Support development of new tools and enable their timely and effective use Protect and promote human rights in TB prevention, care and control Targets MDG 6, Target 8: Halt and begin to reverse the incidence of TB by 2015 Targets linked to the MDGs and endorsed by the Stop TB Partnership: by 2015: reduce prevalence and deaths due to TB by 50% compared with a baseline of 1990 by 2050: eliminate TB as a public health problem

Components of the Stop TB strategy 1. Pursue high-quality DOTS expansion and enhancement Secure political commitment, with adequate and sustained financing Ensure early case detection, and diagnosis through quality-assured bacteriology Provide standardized treatment with supervision, and patient support Ensure effective drug supply and management

4 Monitor and evaluate performance and impact 2. Address TB-HIV, MDR-TB, and the needs of poor and vulnerable populations Scale-up collaborative TB/HIV activities Scale-up prevention and management of multidrug-resistant TB (MDR-TB) Address the needs of TB contacts, and of poor and vulnerable populations 3. Contribute to health system strengthening based on primary health care Help improve health policies, human resource development, financing, supplies, service delivery and information Strengthen infection control in health services, other congregate settings and households Upgrade laboratory networks, and implement the Practical Approach to Lung Health (PAL) Adapt successful approaches from other fields and sectors, and foster action on the social determinants of health 4. Engage all care providers Involve all public, voluntary, corporate and private providers through PublicPrivate Mix (PPM) approaches Promote use of the International Standards for Tuberculosis Care (ISTC) 5. Empower people with TB, and communities through partnership Pursue advocacy, communication and social mobilization Foster community participation in TB care, prevention and health promotion Promote use of the Patients' Charter for Tuberculosis Care 6. Enable and promote research Conduct programme-based operational research Advocate for and participate in research to develop new diagnostics, drugs and vaccines

Ageing and health: Good health adds life to years The topic of World Health Day in 2012 is Ageing and health with the theme "Good health adds life to years". The focus is how good health throughout life can help older men and women lead full and productive lives and be a resource for their families and communities. Ageing concerns each and every one of us whether young or old, male or female, rich or poor no matter where we live. Pharmacist is now an active partner in TB care and control A Joint statement by the World Health Organization (WHO) and the International Pharmaceutical Federation (FIP) on Engaging Pharmacists in TB care and control has been signed on 4th September 2011 at Hyderabad, India during FIP congress.In India IPA is working to engage Pharmacists in collaboration with State TB Control Division, AIOCD, Drugs Control Authorities. The first project was implemented successfully and now expanding in other states like- Madhya Pradesh, Odisha etc. Forthcoming Event CELEBRATION OF WORLD HEALTH DAY

Seminar on Role of Pharmacists in TB Care and Control & th Release of 5 Anniversary issue of Drug Information Bulletin
Organized by: IPA, Bengal Branch Date: 7th April 2012 Time: 5.30 pm Venue: IPA Auditorium Speakers: Dr. Sandip Roy, M O, State TB Cell, Govt. of West Bengal & Dr. D. Chattopadhyay, Assistant Director, Indian Council of Medical Research, Kolkata Unit.