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What is a synapse: Junction Impulse are transmitted o Nerve to nerve o Nerve to muscle o Nerve to glands Types of synapses 1. Where the synapse is located
2.
Inhibitory: 3. Type of transmitter a. Electrical b. Chemical Cl- channels open Inhibition of transmission Transmitters: o Gamma-aminobutyric acid (GABA) o Serotonin
Function of synapses Determine direction of signal Perform a selective action Memory o Facilitation
4.
Excitatory: Na+ (other cations) channels open Transmits an action potential Transmitters: o Acetylcholine o Norepinephrine
Neurotransmitters Receptors
What are neurotransmitters? Types of neurotransmitters: Small molecule rapidly acting o Acute responses o Synthesized in the cytosol of the pre-synaptic terminal o Vesicles are recycled
4 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay
Neuropeptides o More prolonged actions o Synthesized in the neuronal cell body o Vesicles are autolyzed
Examples of neurotransmitters:
Types of receptors: Excitatory or inhibitory o Excitatory receptors: Na+ (other cations) channels open Transmits an action potential o Inhibitory receptors Cl- channels open Inhibition of transmission
Ion channels vs. Second messenger o Ion channels Allows entry/ exit of ions
Neuromuscular junction
Types of reflexes Monosynaptic o Stretch reflex o Single synapse o Example: Knee-jerk reflex
Reflexes
Basic unit: reflex arc