You are on page 1of 9

Synapse & reflexes

1 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

What is a synapse: Junction Impulse are transmitted o Nerve to nerve o Nerve to muscle o Nerve to glands Types of synapses 1. Where the synapse is located

2.

Types of post-synaptic cell

2 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

Inhibitory: 3. Type of transmitter a. Electrical b. Chemical Cl- channels open Inhibition of transmission Transmitters: o Gamma-aminobutyric acid (GABA) o Serotonin

Function of synapses Determine direction of signal Perform a selective action Memory o Facilitation

How is the impulse transmitted?

4.

Excitatory or inhibitory a. Transmitter b. Ion

Excitatory: Na+ (other cations) channels open Transmits an action potential Transmitters: o Acetylcholine o Norepinephrine

3 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

Neurotransmitters Receptors

What are neurotransmitters? Types of neurotransmitters: Small molecule rapidly acting o Acute responses o Synthesized in the cytosol of the pre-synaptic terminal o Vesicles are recycled
4 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

Neuropeptides o More prolonged actions o Synthesized in the neuronal cell body o Vesicles are autolyzed

Examples of neurotransmitters:

5 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

Types of receptors: Excitatory or inhibitory o Excitatory receptors: Na+ (other cations) channels open Transmits an action potential o Inhibitory receptors Cl- channels open Inhibition of transmission

Ion channels vs. Second messenger o Ion channels Allows entry/ exit of ions

6 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

Second messenger Activate a substance in the cytoplasm

Neuromuscular junction

7 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

8 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

Types of reflexes Monosynaptic o Stretch reflex o Single synapse o Example: Knee-jerk reflex

Reflexes
Basic unit: reflex arc

Polysynaptic o Multiple synapses o Example: Withdrawal reflex

9 ADC- KAFC: UPH DJGTMU | Synapse & reflexes by Dr. Babsa-ay

You might also like