UNIVERSIDAD PRIVADA DE HUANCAYO FRANKLIN ROOSEVELT

RESOLUCIN N517-2010-CONAFU

CARRERA PROFESIONAL DE CIENCIAS FARMACUTICAS Y BIOQUMICA

TRABAJO DE BROMATOLOGIA

DOCENTE: LUIS ARTICA MALLQUI PERTENECE: MAMANI PALACIOS, DIVA SEMESTRE: VI TURNO: DIURNO

HUANCAYO 2013

5 CARBOHIDRATOS IMPORTANTES

O H HO H H OH H OH OH OH

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C6 H12 O6 = 180.156 = C(40.00%) H(6.71%) O(53.29%) = 37.54 0.3 cm 3 = 113.9 3.0 cm 3 = 352.9 4.0 cm 3 = 1.573 0.02 = 92.0 3.0 dyne/cm = 1.581 0.06 g/cm 3 = Not available = 14.88 0.5 10-24cm3 = 180.06339 Da = 180 Da = 180.157763 Da

D-Glucose

OH O H OH OH OH

HO H H

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C12 H24 O12 = 360.312 = C(40.00%) H(6.71%) O(53.29%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 360.12678 Da = 360 Da = 360.315527 Da

D-Fructose

O HO HO H H H H OH OH OH

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C18 H36 O18 = 540.468 = C(40.00%) H(6.71%) O(53.29%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 540.19017 Da = 540 Da = 540.47329 Da

D-Mannose
O H HO HO H OH H H OH OH
Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass = C6 H12 O6 = 180.156 = C(40.00%) H(6.71%) O(53.29%) = 37.54 0.3 cm 3 = 113.9 3.0 cm 3 = 352.9 4.0 cm 3 = 1.573 0.02 = 92.0 3.0 dyne/cm = 1.581 0.06 g/cm 3 = Not available = 14.88 0.5 10-24cm3 = 180.06339 Da = 180 Da = 180.157763 Da

D-Galactose

O H H H OH OH OH OH

D-Ribose

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C11 H22 O11 = 330.286 = C(40.00%) H(6.71%) O(53.29%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 330.116215 Da = 330 Da = 330.289233 Da

5 VITAMINAS IMPORTANTES
Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume
OH

H3C

CH3

CH3

CH3

= C20 H30 O = 286.452 = C(83.86%) H(10.56%) O(5.59%) = 95.49 0.3 cm 3 = 300.0 3.0 cm 3 = 738.0 6.0 cm 3 = 1.549 0.02 = 36.6 3.0 dyne/cm = 0.954 0.06 g/cm 3 = Not available = 37.85 0.5 10-24cm3 = 286.229665 Da = 286 Da = 286.459321 Da

CH3

Vitamin A Retinol

Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

H 2N O H2N H3C H 3C O NH2H C 3 H3C O

O H2N H 3C N N Co N
+

O NH2 O

CH3

N N

CH3 CH3

CH3 O

NH

NH2 CH3 CH3

O N P O HO N O H H H O H

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C63 H88 Co N14 O14 P = 1355.366 = C(55.83%) H(6.54%) Co(4.35%) N(14.47%) O(16.53%) P(2.29%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 1354.567407 Da = 1354 Da = 1355.388564 Da

HO

Vitamin B12

HO O HO HO O

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C6 H8 O6 = 176.124 = C(40.92%) H(4.58%) O(54.50%) = 35.26 0.3 cm3 = 90.1 3.0 cm3 = 310.3 6.0 cm3 = 1.711 0.02 = 140.5 3.0 dyne/cm = 1.954 0.06 g/cm3 = Not available = 13.97 0.5 10-24cm3 = 176.03209 Da = 176 Da = 176.12586 Da

OH

Vitamin C l-Ascorbic Acid

H3C CH3 H

CH3 CH3

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C27 H44 O = 384.638 = C(84.31%) H(11.53%) O(4.16%) = 121.27 0.4 cm 3 = 396.9 5.0 cm3 = 979.4 6.0 cm3 = 1.523 0.03 = 37.0 5.0 dyne/cm = 0.96 0.1 g/cm 3 = Not available = 48.07 0.5 10-24cm3 = 384.339215 Da = 384 Da = 384.648243 Da

H CH2 HO

Vitamin D3
CH3 HO H3C CH3 O CH3 CH3 CH3 CH3 CH3

Molecular Formula = C29 H50 O2 Formula Weight = 430.706 Composition = C(80.87%) H(11.70%) O(7.43%) Molar Refractivity = 135.06 0.3 cm3 Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass = 462.7 3.0 cm3 = 1123.0 4.0 cm3 = 1.495 0.02 = 34.6 3.0 dyne/cm = 0.930 0.06 g/cm3 = Not available = 53.54 0.5 10-24cm3 = 430.38108 Da = 430 Da = 430.717478 Da

Vitamin E -Tocopherol

5 ESTEROIDES IMPORTANTES

H3C
12

21 20 17

22 23

24 25

CH3

26

CH3
13

18

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= = = = = = = = = = = = =

C27 H48 372.670 C(87.02%) H(12.98%) 118.76 0.3 cm 3 972.0 6.0 cm 3 1.492 0.02 31.8 3.0 dyne/cm 0.910 0.06 g/cm 3 2.38 0.1 47.08 0.5 10-24cm3 372.3756 Da 372 Da 372.680842 Da

H
16

1 2 3 4

CH3
10 5

19

11 9

CH3
27

= 409.1 3.0 cm 3

H
8

14

15

H
6

Cholestane

H3C H3C
12 21 22 20 17 23 18 13

28 24 25

CH3
27

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C28 H50 = 386.697 = C(86.97%) H(13.03%) = 123.35 0.3 cm 3 = 426.0 3.0 cm 3 = 1010.0 6.0 cm 3 = 1.490 0.02 = 31.5 3.0 dyne/cm = 0.907 0.06 g/cm 3 = 2.37 0.1 = 48.90 0.5 10-24cm3 = 386.39125 Da = 386 Da = 386.70783 Da

CH3

H
16

1 2 3 4

CH3
10 5

19

11

CH3
26

H
9 8 14 15

H
6

Ergostane

H3 C
12

21

H
20 17

34 22 23

CH3
24 25

28

CH3
26

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C30 H52 = 412.734 = C(87.30%) H(12.70%) = 130.54 0.3 cm3 = 439.4 3.0 cm3 = 1054.9 6.0 cm3 = 1.505 0.02 = 33.2 3.0 dyne/cm = 0.939 0.06 g/cm3 = 2.48 0.1 = 51.75 0.5 10-24cm3 = 412.4069 Da = 412 Da = 412.745856 Da

CH3
13

18

H CH3
33 16

1 2 3 4

CH3
10 5

19

11 9

CH3
27

H
8

14

15

H
6

Gorgostane
18 13
Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass = C49 H84 = 673.191 = C(87.42%) H(12.58%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 672.6573 Da = 672 Da = 673.210787 Da

12

CH3
17 16 14 15

1 2 3 4

CH3
10 5

19

11 9

H
8

H
6

Androstane
H
12 11 1 2 3 4 13 17 16 14 15
Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass = C17 H28 = 232.404 = C(87.86%) H(12.14%) = 72.55 0.3 cm 3 = 244.6 3.0 cm 3 = 586.8 4.0 cm 3 = 1.504 0.02 = 33.1 3.0 dyne/cm = 0.949 0.06 g/cm 3 = 2.19 0.1 = 28.76 0.5 10-24cm3 = 232.2191 Da = 232 Da = 232.410954 Da

H
10 5

H
8

H
6

Gonane

3 ALCALOIDES IMPORTANTES
H
12 17 1 2 3 20 4 19 11 10 13 16
Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass = C18 H27 N = 257.414 = C(83.99%) H(10.57%) N(5.44%) = 76.62 0.4 cm 3 = 225.2 5.0 cm3 = 582.3 6.0 cm3 = 1.595 0.03 = 44.7 5.0 dyne/cm = 1.14 0.1 g/cm 3 = Not available = 30.37 0.5 10-24cm3 = 257.214349 Da = 257 Da = 257.420738 Da

H
9 8

14

NH
5 6 7

H H

15

aconitane
16 10 1 2 3 4 11 12 15 13 5 6 9 14 17

NH H
8 7

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C16 H21 N = 227.345 = C(84.53%) H(9.31%) N(6.16%) = 70.53 0.4 cm 3 = 206.7 5.0 cm3 = 534.5 6.0 cm3 = 1.598 0.03 = 44.7 5.0 dyne/cm = 1.09 0.1 g/cm 3 = Not available = 27.96 0.5 10-24cm3 = 227.167399 Da = 227 Da = 227.350808 Da

morphinan

H CH3 O
6 7 8 13

4 4a 12a 3 2

O
5 5a 12b 8a 9

OH

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C17 H21 N O3 = 287.354 = C(71.06%) H(7.37%) N(4.87%) O(16.70%) = 80.31 0.4 cm 3 = 223.9 5.0 cm 3 = 614.3 6.0 cm 3 = 1.636 0.03 = 56.6 5.0 dyne/cm = 1.28 0.1 g/cm 3 = Not available = 31.83 0.5 10-24cm3 = 287.152144 Da = 287 Da = 287.359761 Da

1 12 11

10

CH3

14

galanthamine

8 AMINOACIDOS IMPORTANTES
O
Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass = C9 H11 N O = 149.190 = C(72.46%) H(7.43%) N(9.39%) O(10.72%) = 44.11 0.3 cm 3 = 140.1 3.0 cm 3 = 358.9 4.0 cm 3 = 1.542 0.02 = 43.0 3.0 dyne/cm = 1.064 0.06 g/cm 3 = Not available = 17.48 0.5 10-24cm3 = 149.084064 Da = 149 Da = 149.193096 Da

NH2

Phenylalanyl (Phe)

O H2 N NH2 OH

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C6 H14 N2 O2 = 146.188 = C(49.30%) H(9.65%) N(19.16%) O(21.89%) = 38.43 0.3 cm 3 = 129.9 3.0 cm 3 = 348.1 4.0 cm 3 = 1.503 0.02 = 51.5 3.0 dyne/cm = 1.125 0.06 g/cm 3 = Not available = 15.23 0.5 10-24cm3 = 146.105528 Da = 146 Da = 146.189941 Da

Lysine (Lys)

O H3 C S NH2 OH

Methionine (Met)

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C11 H25 N3 O4 S = 295.400 = C(44.73%) H(8.53%) N(14.22%) O(21.66%) S(10.86%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 295.156578 Da = 295 Da = 295.402583 Da

CH3 O HO NH2 OH

Threonine (Thr)

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C15 H34 N4 O7 S = 414.519 = C(43.46%) H(8.27%) N(13.52%) O(27.02%) S(7.74%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 414.214822 Da = 414 Da = 414.523152 Da

O OH NH NH2

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C11 H12 N2 O2 = 204.225 = C(64.69%) H(5.92%) N(13.72%) O(15.67%) = 57.76 0.3 cm 3 = 149.8 3.0 cm 3 = 435.3 4.0 cm 3 = 1.697 0.02 = 71.1 3.0 dyne/cm = 1.362 0.06 g/cm 3 = Not available = 22.90 0.5 10-24cm3 = 204.089878 Da = 204 Da = 204.229174 Da

Tryptophan (Trp)

CH3 O H3 C NH2 OH

Valine (Val)

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C16 H23 N3 O4 = 321.372 = C(59.80%) H(7.21%) N(13.08%) O(19.91%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 321.168857 Da = 321 Da = 321.377427 Da

NH2 HN NH

O OH NH2

Arginine (Arg)

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C22 H37 N7 O6 = 495.573 = C(53.32%) H(7.53%) N(19.78%) O(19.37%) = Not available = Not available = Not available = Not available = Not available = Not available = Not available = Not available = 495.280533 Da = 495 Da = 495.580814 Da

CH3 O H3 C NH2 OH

Molecular Formula Formula Weight Composition Molar Refractivity Molar Volume Parachor Index of Refraction Surface Tension Density Dielectric Constant Polarizability Monoisotopic Mass Nominal Mass Average Mass

= C6 H13 N O2 = 131.173 = C(54.94%) H(9.99%) N(10.68%) O(24.39%) = 34.86 0.3 cm 3 = 126.6 3.0 cm3 = 316.4 4.0 cm3 = 1.462 0.02 = 39.0 3.0 dyne/cm = 1.035 0.06 g/cm 3 = Not available = 13.82 0.5 10-24cm3 = 131.094629 Da = 131 Da = 131.175242 Da

Isoleucine (Ile)