Sample Midterm BICD 110 Cell Biology

1. Multiple choices (20 questions) (20%) (Circle the letter next to the correct answer) 1). The following modification occurs on nuclear lamins, which cause nuclear lamina to disassemble and nuclear envelo e to be redistributed during cell c!cle" a. #$lin%ed gl!cos!lation b. &$lin%ed gl!cos!lation c. 'hos hor!lation d. (!ristalation 2). The function of the phospholipid exchange (transfer) proteins is: a. Flipping phospholipids from one leaflet to another b. Catalyzing glycosylation of phospholipids c. Moving newly synthesized phospholipids from smooth ER to other membrane compartments d. Transfer lipids into cell nucleus

2.

rue or !alse (10 questions) (20%)

))))))))1). *am brush chromosomes are mitotic chromosomes. ))))))))2). 'roteins ta%e u most of a cell+s dr! weight.

". #illing the $lan%s (10 questions) (20%) 1). The ,0 nm fiber, found in inter hase chromosomes can be unfolded a structure called )))))))))))))))))))))))))))) with nucleosome core articles and -#./ 2). The most common secondar! structure of the transmembrane domains of membrane$ s anning roteins is )))))) ))))))))/

01C-110 (idterm ('rof. 2imin 3ou) &. '(periments (t)o e(periments) (10%) 1) .s shown in the diagram below, when a mouse cell and a human cell are induced to fuse into one h!brid cell, the membrane roteins from the two different cells were found intermixed with each other all over the fused cell.

01C-110 (idterm ('rof. 2imin 3ou) a) 4hat was the main conclusion of this classical ex eriment5 b) 'lease briefl! describe another ex eriment that can rovide more 6uantitative measurement of this feature of membranes and membrane roteins that the above$ mentioned ex eriment reveals

*. +ame the structures (t)o questions) (10%) 1). 'lease name the three im ortant structures on eu%ar!otic chromosomes indicated as 1, 2 and ,.

01C-110 (idterm ('rof. 2imin 3ou)

1 )))))))))))))))))))))))))) 2 )))))))))))))))))))))))))) , ))))))))))))))))))))))))))

01C-110 (idterm ('rof. 2imin 3ou) ,. Short ans)ers (t)o questions) (20-) The following diagram shows rotein translocation into a mitochondrian.

a. 8x lain where energ! is introduced to allow directed trans ort. b. 1ndicate where the T&( com lex and the T1(2, com lex are located.