Model Test Paper 2013 B.Sc.-III Biotech.

Genome Analysis
Points to remember: 1. Write answer precisely as no supplementary answer book will be given to any candidate. 2. All the parts of one question should be answered at one place only .one complete answer should not be answered at different places in the answer book. 3. Write down the section and question number. 4. Question 1. is compulsory to attempt. 5. It is compulsory to attempt one question from each section. In all including the first question attempt five questions. Q1. Answer the following (each carries one mark) (i)Define:(a) (b) (c) (d) (e) RFLP VNTR SNP QTL SSLP

(II) (a) Human genome project was started in ___________. (b) ___________number of genes are found in rice according to rice genome project. (c) Give two examples of PCR based markers ___________ and ___________. (d) More the distance between two genes more are the chances of ___________. (e) Give an application of RAPD.
(Sec-A)

Q2. Describe the linkage analysis in Drosophila or Neurospora.

Q3. Describe the chromatin model of chromosome structure.

(Sec-B)

Q4. Differentiate between genetic mapping and physical mapping? Q5. Define restriction mapping. Taking an example describe the procedure.
(Sec-C)

Q6. Write short notes on: (a) QTL (b) GISH Q7. Define exon trapping. Describe the technique.
(Sec-D)

Q8. Describe the current status and future perspective of Rice genome project. Q9. Give a detailed account on human genome project and its applications.