Driving distance from, Tuscaloosa, AL to Panama City Beach is 280 Miles / 451 Km. How many hours? 4 hours 57 mins. I would put about $130.00 of gas in my car . The Legacy Hotel $127 Rooms at Legacy by the Sea. Up to 60% Off in Panama City Beach! The hotel have 3 stars. The best beach this side of paradise, Panama City Beach Florida offers 27 miles of stunning white sand, emerald green waters and surefire enjoyment in, on or under the water. Legacy by the Sea Gulf-front hotel located on the gulf and close to shopping and nightlife. If I do stay, I will stay the entire weekend. Me & my Best Friend. Shelter= $254.00 In the water. I would love to get in the water & swim with the Dolphins. Dolphins are harmless creatures & theyre kind . Food Davids New Orleans Style Snow-Balls All this looks so good. I Cant wait until I go to Panama. Its going to be me & two of my best friends. Tinkk & Kink. We have $100 apiece for food. We can eat at any restaurant we want. FOOD= $300 in all Shopping Me & my girls are going to the Mall & ball out ! We might spend about 500 apiece. In all= $1,500 WERE HERE!!