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    This document provides a chart with dosing guidelines for anesthetizing laboratory rats with ketamine and xylazine. The chart lists recommended doses of ketamine at 80mg/kg and xylazine at 10mg/kg based on the rat's body weight ranging from 100gm to 500gm. It also specifies the required volume of each drug in milliliters and units to administer for proper dosing. Stock concentrations and unit conversions are noted at the bottom.

    Original Description:

    In laboratory, Ketamine and Xylazine are being used to anaesthetise the rat. The anesthetic dose for ketamine and xylazine is 80mg/kg and 10mg/kg body weight respectively. Generally, the stock solution concentration of aforesaid drugs (while buying from medical shops) is 50mg/ml for ketamine, 20mg/ml for xylazine. This page gives the information about required volume of ketamine and xylazine from stock solution for the given rat (as per weight).

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    Anesthetic Drug Dose Chart for Laboratory Rat

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    This document provides a chart with dosing guidelines for anesthetizing laboratory rats with ketamine and xylazine. The chart lists recommended doses of ketamine at 80mg/kg and xylazine at 10mg/kg based on the rat's body weight ranging from 100gm to 500gm. It also specifies the required volume of each drug in milliliters and units to administer for proper dosing. Stock concentrations and unit conversions are noted at the bottom.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    33 views1 page

    Anesthetic Drug Dose Chart For Laboratory Rat

    Uploaded by

    SHANRUSHIA
    This document provides a chart with dosing guidelines for anesthetizing laboratory rats with ketamine and xylazine. The chart lists recommended doses of ketamine at 80mg/kg and xylazine at 10mg/kg based on the rat's body weight ranging from 100gm to 500gm. It also specifies the required volume of each drug in milliliters and units to administer for proper dosing. Stock concentrations and unit conversions are noted at the bottom.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    ANESTHETIC DRUG DOSE CHART FOR LABORATORY RAT

    ANESTHETIC DOSE: Ketamine - 80mg/kg & Xylazine - 10mg/kg


    Animal Weight
    100gm
    110gm
    120gm
    130gm
    140gm
    150gm
    160gm
    170gm
    180gm
    190gm
    200gm
    210gm
    220gm
    230gm
    240gm
    250gm
    260gm
    270gm
    280gm
    290gm
    300gm
    310gm
    320gm
    330gm
    340gm
    350gm
    360gm
    370gm
    380gm
    390gm
    400gm
    410gm
    420gm
    430gm
    440gm
    450gm
    460gm
    470gm
    480gm
    490gm
    500gm

    Ketamine Dose
    8mg
    8.8mg
    9.6mg
    10.4mg
    11.2mg
    12mg
    12.8mg
    13.6mg
    14.4mg
    15.2mg
    16mg
    16.8mg
    17.6mg
    18.4mg
    19.2mg
    20mg
    20.8mg
    21.6mg
    22.4mg
    23.2mg
    24mg
    24.8mg
    25.6mg
    26.4mg
    27.2mg
    28mg
    28.8mg
    29.6mg
    30.4mg
    31.2mg
    32mg
    32.8mg
    33.6mg
    34.4mg
    35.2mg
    36mg
    36.8mg
    37.6mg
    38.4mg
    39.2mg
    40mg

    Required Volume
    ml

    units

    0.16
    0.18
    0.19
    0.21
    0.22
    0.24
    0.26
    0.27
    0.29
    0.30
    0.32
    0.34
    0.35
    0.37
    0.38
    0.40
    0.42
    0.43
    0.45
    0.46
    0.48
    0.50
    0.51
    0.53
    0.54
    0.56
    0.58
    0.59
    0.61
    0.62
    0.64
    0.66
    0.67
    0.69
    0.70
    0.72
    0.74
    0.75
    0.77
    0.78
    0.80

    6
    6.6
    7.2
    7.8
    8.4
    9
    9.6
    10.2
    10.8
    11.4
    12
    12.6
    13.2
    13.8
    14.4
    15
    15.6
    16.2
    16.8
    17.4
    18
    18.6
    19.2
    19.8
    20.4
    21
    21.6
    22.2
    22.8
    23.4
    24
    24.6
    25.2
    25.8
    26.4
    27
    27.6
    28.2
    28.8
    29.4
    30

    Xylazine Dose
    1mg
    1.1mg
    1.2mg
    1.3mg
    1.4mg
    1.5mg
    1.6mg
    1.7mg
    1.8mg
    1.9mg
    2mg
    2.1mg
    2.2mg
    2.3mg
    2.4mg
    2.5mg
    2.6mg
    2.7mg
    2.8mg
    2.9mg
    3mg
    3.1mg
    3.2mg
    3.3mg
    3.4mg
    3.5mg
    3.6mg
    3.7mg
    3.8mg
    3.9mg
    4mg
    4.1mg
    4.2mg
    4.3mg
    4.4mg
    4.5mg
    4.6mg
    4.7mg
    4.8mg
    4.9mg
    5mg

    Required Volume
    ml

    units

    0.05
    0.055
    0.06
    0.065
    0.07
    0.075
    0.08
    0.085
    0.09
    0.095
    0.1
    0.105
    0.11
    0.115
    0.12
    0.125
    0.13
    0.135
    0.14
    0.145
    0.15
    0.155
    0.16
    0.165
    0.17
    0.175
    0.18
    0.185
    0.19
    0.195
    0.2
    0.205
    0.21
    0.215
    0.22
    0.225
    0.23
    0.235
    0.24
    0.245
    0.25

    2
    2.2
    2.4
    2.6
    2.8
    3
    3.2
    3.4
    3.6
    3.8
    4
    4.2
    4.4
    4.6
    4.8
    5
    5.2
    5.4
    5.6
    5.8
    6
    6.2
    6.4
    6.6
    6.8
    7
    7.2
    7.4
    7.6
    7.8
    8
    8.2
    8.4
    8.6
    8.8
    9
    9.2
    9.4
    9.6
    9.8
    10

    Note: Stock Concentration: Ketamine - 50mg/ml, Xylazine - 20mg/ml, 1 ml = 40 units

    Prepared By: Annadurai Shanmuganathan, Ph.D Student, University of Madras

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