PICU protocols from Drug Doses" by Frank Shann.

Intensive Care Unit,

Royal Children's Hospital 14th edition
Gentamicin. IV or IM. 1wk-10yr: 8mg/kg day 1, then 6 mg/kg daily. >10yr:
7mg/kg day 1, then 5mg/kg (max 240-360mg) daily. Neonate, 5mg/kg dose:
<1200g 48H (0-7 days of life), 36H (8-30 days), 24H (>30days); 1200-2500g
36H (0-7 days of life), 24H (>7 days); term 24H (0-7 days of life), then as for
1wk-10yr. Trough level <1.0mg/L.
Amikacin. Single daily dose IV or IM. Neonate: 15mg/kg stat, then 7.5mg/kg
(<30wk) 10mg/kg (30-35wk) 15 mg/kg (term <1wk) daily. 1wk-10yr: 25mg/kg
day 1, then 18mg/kg daily. >10yr: 20mg/kg day 1, then 15mg/kg (max 1.5g)
daily. Trough level <5.0mg/L (RCH sent to St.Vs)
Vancomycin. 10mg/kg (adult 500mg) 6H IV over 1hr, or 1g 12H in adult IV
over 2hr. Newborn: 10mg/kg 8H IV over 1hr. C.difficile: 10mg/kg (adult
500mg) 6H oral. Intraventric (NOT/kg): 10mg 48H. Trough 5-10mg/L (peak
20-40mg/L).