Georley Joy R.

Lobrido BN4-A
Angelica Elixee G. Lopez BN4-A

January 22, 2015

DRUG STUDY

Name of Drug

Dosage/ Route/
Frequency

Mechanism of
action

Indications

Contraindications

Generic Name:
lansoprazole

Dosage:
30 mg

Brand Name:
Prevacid

Route:
PO
Frequency:
OD

Short-term
treatment of active
duodenal ulcer
Short-term
treatment of
gastroesophageal
reflux disease:
severe erosive
esophagitis; poorly
responsive
symptomatic
gastroesophageal
reflux disease
Treatment of
pathological
hypersecretory
conditions, longterm therapy

Contraindicated
with hypersensitivity
to lansoprazole or
any of its
components.

Classifications:
Antisecretory drug
Proton pump inhibitor

Gastric pump
inhibitor:
Supresses
gastric acid
secretion by
specific
inhibition of the
hydrogenpotassium
ATPase enzyme
parietal cells;
blocks the final
step of acid
production

Eradication of
Helicobacter pylori
infection in patients
with active or
recurrent duodenal
ulcers in
combination with
clarithromycin and
amoxicillin

-use cautiously with

pregnancy and
lactation

Adverse Reaction
Headache, dizziness,
asthenia, vertigo,
insomnia, anxiety,
paresthesias, dream
abnormalities, Rash,
inflammation,
urticaria, pruritus,
alopecia, dry skin,
acne,
Diarrhea, abdominal
pain, nausea,
vomiting,
constipation, dry
mouth, URI
symptoms, cough,
epistaxis, Gastric
cancer in preclinical
studies, back pain,
fever

Nursing Responsibility

1. Administer before
meals.
2. Caution patient to
swallow capsules
whole, not to open,
chew, or crush. If
patient has difficulty
swallowing, open
capsule and sprinkle
granules on apple sauce
or use granules, which
can be added to 30ml
water, stirred and drunk
immediately
3. If using orally
disintegrating tablet,
place on your tongue
and allow to dissolve.
Follow with a drink of
water.
4. Arrange to have a
regular follow-up care
while you are taking
this drug.