DRUG MODE OF ACTION INDICATION ADVERSE EFFECTS NURSING

RESPONSIBILITIES
Generic Name: It relaxes vascular Indicated to improve  Hypotension  It is very
nitric oxide smooth muscle by oxygenation and  Withdrawal important that
(inhalation gas) binding to the heme reduce the need for your baby's
 Atelectasis
moiety of cytosolic doctor check
extracorporeal  Hematuria
Brand Name: guanylate cyclase, your baby
INOmax activating guanylate membrane oxygenation  Hyperglycemia closely while
cyclase and in term and near-  Sepsis receiving
Dosage/Route/Frequency increasing term (>34 weeks  Infection nitric oxide.
20 ppm intracellular levels gestation) neonates  Cellulitis This will
of cyclic-guanosine with hypoxic  Stridor allow the
Classification: 3',5'-monophosphate, respiratory failure doctor to see
 Pulmonary Vasodilator which then leads to if the
associated with
vasodilation. medicine is
clinical or
working
echocardiographic properly and
evidence of to decide if
pulmonary your baby
hypertension in should
conjunction with continue to
ventilatory support receive it.
Blood tests
and other
may be needed
appropriate agents. to check for
unwanted
CONTRAINDICATIONS
effects.
Congenital heart  Your baby's
disease doctor also
needs to
characterized by
monitor your
ductal dependent baby's
systemic blood flow breathing,
(eg, interrupted oxygen levels,
aortic arch, and other
critical aortic vital signs
while
stenosis,
receiving
hypoplastic left nitric oxide.
heart syndrome) and  Stopping
severe left nitric oxide
ventricular suddenly may
dysfunction. increase your
baby's risk to
have rebound
pulmonary
hypertension
syndrome.
Symptoms
include:
bluish lips or
skin, slow
heartbeat,
lightheadednes
s, dizziness,
or fainting,
or decreased
cardiac
output.
 Nitric oxide
may cause a
rare, but
serious blood
problem called
methemoglobine
mia. Your
baby's doctor
 will measure
how much
methemoglobin
is in your
baby's blood
while
receiving
nitric oxide.
 Do not take
other
medicines
unless they
have been
discussed with
your doctor.
This includes
prescription
or
nonprescriptio
n (over-the-
counter [OTC])
medicines and
herbal or
vitamin
supplements.