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Drug Name Dosages Therapeutic Indications Adverse effects Contraindicatio Nursing considerations
Actions ns
atenolol Available forms: Blocks beta- Treatment of Allergic reactions: Contraindicate Assessment
(a ten' o lole) Tablets—25, 50, 100 adrenergic angina Pharyngitis, d with sinus History: Sinus
Apo-Atenolol mg; injection—5 receptors of the pectoris due to erythematous rash, bradycardia, bradycardia, second- or
(CAN), Gen- mg/10 mL sympathetic coronary fever, sore throat, second- or third-degree heart block,
Atenolol (CAN), nervous system atherosclerosi laryngospasm, third-degree cardiogenic shock, CHF,
Novo-Atenol ADULTS in the heart and s respiratory distress heart block, renal failure, diabetes or
(CAN), Hypertension: juxtaglomerular cardiogenic thyrotoxicosis, lactation,
Tenormin Initially, 50 mg PO apparatus Hypertension, CNS: Dizziness, shock, CHF, pregnancy
once a day; after 1– (kidney), thus as a step 1 vertigo, tinnitus, pregnancy. Physical: Baseline
Pregnancy 2 wk, dose may be decreasing the agent, alone fatigue, emotional weight, skin condition,
Category D increased to 100 excitability of the or with other depression, Use cautiously neurologic status, P,
mg/day. heart, drugs, paresthesias, sleep with renal BP, ECG, respiratory
Drug classes Angina pectoris: decreasing especially disturbances, failure, status, renal and thyroid
Beta1- Initially, 50 mg PO cardiac output diuretics hallucinations, diabetes or function tests, blood and
selective daily. If optimal and oxygen disorientation, thyrotoxicosis urine glucose,
adrenergic consumption, Treatment of memory loss, (atenolol can cholesterol, triglycerides
response is not
blocker decreasing the MI slurred speech mask the
achieved in 1 wk,
Antianginal increase to 100 mg release of renin usual cardiac Interventions
from the kidney, Unlabeled CV: Bradycardia, signs of
daily; up to 200 WARNING: Do not
Antihyperten and lowering BP. uses: CHF, cardiac hypoglycemia
mg/day may be discontinue drug
sive Prevention of arrhythmias, and
needed. abruptly after long-term
migraine sinoatrial or AV thyrotoxicosis) therapy (hypersensitivity
headaches; nodal block, , lactation,
Acute MI: Initially, 5 to catecholamines may
alcohol tachycardia, respiratory
mg IV given over 5 have developed,
withdrawal peripheral vascular disease.
min as soon as causing exacerbation of
syndrome, insufficiency,
possible after angina, MI, and
treatment of claudication, CVA,
diagnosis; follow ventricular arrhythmias).
ventricular and pulmonary edema,
with IV injection of 5 Taper drug gradually
supraventricul hypotension
mg 10 min later. over 2 wk with
ar arrhythmias
Switch to 50 mg PO monitoring.
Dermatologic:
10 min after the last Consult physician about
Rash, pruritus,
IV dose; follow with withdrawing drug if
sweating, dry skin
50 mg PO 12 hr patient is to undergo
later. Thereafter, surgery (withdrawal is
EENT: Eye
administer 100 mg controversial).
irritation, dry eyes,
PO daily or 50 mg
conjunctivitis,
PO bid for 6–9 days Teaching points
blurred vision
or until discharge Take drug with meals if
from the hospital. GI: Gastric pain, GI upset occurs.
flatulence, Do not stop taking this
PEDIATRIC PATIENTS constipation, drug unless told to do so
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Safety and efficacy diarrhea, nausea, by a health care
not established. vomiting, anorexia, provider.
ischemic colitis,
renal and Avoid driving or
mesenteric arterial dangerous activities if
thrombosis, dizziness or weakness
retroperitoneal occurs.
fibrosis,
hepatomegaly, You may experience
acute pancreatitis these side effects:
Dizziness, light-
GU: Impotence, headedness, loss of
decreased libido, appetite, nightmares,
Peyronie's disease, depression, sexual
dysuria, nocturia, impotence.
frequent urination
Report difficulty
Musculoskeletal: breathing, night cough,
Joint pain, swelling of extremities,
arthralgia, muscle slow pulse, confusion,
cramps depression, rash, fever,
sore throat.
Respiratory:
Bronchospasm,
dyspnea, cough,
bronchial
obstruction, nasal
stuffiness, rhinitis,
pharyngitis (less
likely than with
propranolol)
Other: Decreased
exercise tolerance,
development of
antinuclear
antibodies,
hyperglycemia or
hypoglycemia,
elevated serum
transaminase,
alkaline
phosphatase, and
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LDH