NITROGLYCERIN

CLASSIFICATION INDICATION DOSAGE MECHANISM OF SIDE EFFECTS NURSING

ACTION RESPONSIBILITIES
Use to treat:  Aerosol (translingual): Reduces cardiac oxygen  CNS: 1. Nurse should always
 Prevent 0.4mg/metered spray demand by decreasing - Headache double check if she
Therapeutic Class: chronic angina  Injection: left ventricular end- - Dizziness have the right patient,
Vasodilators, attacks 5mg/ml, 100 mcg/ml, 200 diastolic pressure right medicine, right
- Syncope
Antianginals  Acute angina mcg/ml, 400 mcg/ml (preload) and to a lesser dosage, right route
- Weakness
pectoris; to  Ointment: extent, systemic vascular and right time
Pharmacologic Class: prevent or 0.4%, 2% resistance (afterload).  CV: 2. Monitor vital signs,
Nitrate minimize  Powder(SL): Also increases blood flow - Orthostatic particularly BP, during
angina attacks 400 mcg through the collateral hypotension infusion in pt. with MI
before stressful  Tablets (SL): coronary vessels. - Bradycardia 3. Inform client ahead of
events 0.3 mg (1/200 grain), 0.4 mg - Flushing time prior to
 Moderate to (1/150 grain), 0.6 mg (1/100 - Palpitations administering the
severe pain grain) - Peripheral edema drugs that it would
from chronic  Transdermal patch:  EENT: have an adverse effect
anal fissure 0.1mg/hr., 0.2 mg/hr.,0.3 like headache during
- Pharyngitis
mg/hr.,0.4 mg/hr., 0.6 beginning of therapy,
mg/hr., 0.8 mg/hr., - Rhinitis
if headache persist the
- SL Burning
nurse could administer
 GI: aspirin or
- Abdominal ulcer acetaminophen.
- Nausea, vomiting 4. Nurse should monitor
 RESPIRATORY: if pt. felt any SE if
- Dyspnea headache persist the
nurse may inform the
physician about it so
the dosage will be
reduced temporarily.
5. If drugs in a form of
patches the nurse
should wipe off
nitroglycerin paste/
remove patch before
defibrillation to avoid
pt. burns.