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00 Intro Histology Text
00 Intro Histology Text
INTRODUCTION
Basic Terminology
Histology :
histos - tissue
logos - study of
So, study of tissue.
Might be better defined as the study of the
structure of tissues.
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Tissue is derived from the French word, tissu which means "weave or texture".
Prior to the late 1700s, tissue did not refer to organic, cellular layers, but rather to
anything woven or textured.
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http://home-and-garden.webshots.com/photo/1092738817041241628bWnrML
http://www.southwestschools.org/jsfaculty/Microscopes/history.html
http://www.college-optometrists.org/index.aspx/pcms/site.college.What_We_Do.museyeum.online_exhibitions.microscopy.early/
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http://www.college-optometrists.org/index.aspx/pcms/site.college.What_We_Do.museyeum.online_exhibitions.microscopy.early/
http://www.yesmag.bc.ca/how_work/microscope.html
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http://www.realcork.org/html/prod_cork_properties.php
Additional study revealed that, in living tissues, these compartments were filled with a fluid
substance which is, of course, the cell cytoplasm.
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1 SCHWANN
THEODOR
18103 - 1882
Stains were not used to examine cells in these early studies. Scientists using the microscope relied
entirely on differences in refractive index to make structures in tissues visible.
This didnt work very well - not enough contrast
Initially only the nucleus (nut) of the cell was noted,
but it soon became obvious that there was an even
smaller structure within the nucleus that was given the
name nucleolus which means small nut.
http://faraday.physics.uiowa.edu/movies/MPEG/6a40.30.mpg
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We now know that all the tissues of the body are formed from 4
basic types of tissue.
Epithelial tissue
Connective tissue
Muscle tissue
Nervous tissue
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Definitions
tissues - interwoven masses of cells and extra cellular material
cells - living, more or less self-sufficient entities that form tissues. Surrounded by a
membrane.
organelles - membrane bound structures within cells (e.g. mitochondria, golgi bodies,
lysosomes)
inclusions - various non-membrane bound structures within cells (e.g. glycogen
granules)
molecules and atoms - well, hopefully you know what these are
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and finally,
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cell metabolism.
2. Structural molecules - such as phospholipids and cholesterol,
proteins such as tubulin, actin, myosin, etc. Raw materials for
synthesis and construction of enzymes, membranes, microtubules,
micro-filaments, organelles, cells, etc.
3. Information molecules - DNA, RNA
4. Catalysts, reaction initiators - special proteins called enzymes.
5. Antigenicity - interaction of cell molecular structure with proteins
called immunoglobulins (antibodies - the immune system)
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