ANTIGEN

Killing of bacteria
Inflammation
Inactivation of viruses
Allergy

APC
Antigen
processing
(dendritic cells,
M et al.)
Antigen
"presentation"

B
Antigenspecific
triggering

Proliferation
Differentiation

AFC

ANTIBODY
AUTOIMMUNITY

TH2 T-cell
"help"

T-CELL FUNCTIONS

TC

T-cell killing: virus-infected

cells, transplants

Mixed Lymphocyte Reaction (MLR)

TH1

Delayed type hypersensitivity,

(DTH); e.g. tuberculin reaction

Treg

AFFERENT

CENTRAL

Tolerance, suppression

EFFERENT

THREE "LIMBS" OF THE IMMUNE RESPONSE

01_Roadmap.prz 16 IX 11

Handout #1, 20 September 2011

Complement

Ag/Ab complexes