Cendaa, Lorelyn L.

IMSEROLEC1 /7:30-8:30

Feb.10,2016
Surface Markers on T and B Cells

Antigen

Cell type

Function

Thymocytes
T Cells
NK Cells
Thymocytes
T Cells

Involved in T cell activation

Associated with T-cell antigen receptor

role in TCR signal transduction

Helper T cells
Monocytes
macrophages
Mature T cells
Thymocytes
subset of B cells (B1)
Thymocyte subsets
cytotoxic T cells
B and T cell precursors
bone marrow stromal cells

Coreceptor for MHC class II

receptor for HIV

Positive or negative modulation of T

and B cell receptor signaling

Coreceptor for MHC class 1

Protease
Marker for pre-B CALLA

Macrophages
NK cells
neutrophils
B cells
follicular dendritic cells

Low affinity Fc receptor

Mediates phagocytosis and ADCC

Part of B cell coreceptor, signal

transduction molecule that regulates Bcell development and activation

B cells
follicular dendritic cells
subset of immature thymocytes
B cells
Monocytes
follicular dendritic cells

Receptor for complement component

C3d
Part of B-cell coreceptor with CD19
Regulation of IgE synthesis
Triggers release of II-1, II-6 and GMCSF from monocytes

CD25

Activated T,B cells

monocytes

Receptor for II-2

CD44

Most leukocytes

CD45R

Different forms on all

hematopoietic cells
NK cells
subsets of T cells
NK cells, subsets of T cells

Adhesion molecule mediating homing

to peripheral lymphoid organs
Essential in T and B cell antigentimulated activation
Not known

CD2

CD3
CD4

CD5

CD8
CD10
CD16

CD19

CD21

CD23

CD 56
CD 94

Subunit of NKG2-A complex involved in

inhibition of NK cell cytotoxicity

Reference: Clinical Immunology & Serology: A Laboratory Perspective; Christine Dorresteyn Stevens; pg.24