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DRUG THERAPY of PRIMARY DYSMENORRHEA

DRUG
NSAIDs
* Acetic Acid
- Diclofenac CDOC
- Indomethacin
- Sulindac
* Fenamates
- Mefenamic acid CDOC
* Oxicams
- Piroxicam
* Proprionic acid
- Ibuprofen CDOC
- Naproxen CDOC
- Ketoprofen CDOC
* Salicylic acids
- Diflunisal

USUAL DOSE ( per oral )

100mg then 50mg , 3 x daily


25mg 3 x daily
200mg, 4-6 x daily
500mg then 250mg 4 x daily
20mg daily
400mg 6 x daily
500mg then 250mg 3-4 x daily
50mg 3 x daily
1000mg then 500mg 2 x daily

Combination Oral
Contraceptives

1daily, 28-day cycle pack, progestin


dominant

Cyclooxygenase-2 inhibitor
* Refecoxib

50mg daily for 5 days maximum

@-Adrenergic agonists
* Clonidine

0,1mg 3 x daily

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