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Body

contouring
TIPS and HINTS

Outline
Weight lose medications and remedies:
Herbal remedies (facts and myths).
Novel pharmacological treatment of obesity.
Special populations (pregnancy, lactation, diabetes, CVSd)

Body contouring medications and protocols:

Localized obesity.
Flabiness and stretch marks.
Cellulite.
Breast enlargement medications.

Pediatric obesity

Adulterated products
HAAD LIST

Adulteration with

T3 and
T4

Phencycli
Phenolphtha
Sibutra
dine

Mazind
NMDAlein
mine
RAntag
(laxative
ol )

Psychologic
Cardiovasc Amphetami
ne like
ular events
al Carcinog
(sympatho
12%
mimetic)
enic
dependence

Herbal remedies and


weight loss

Herbal remedies
Laxative
s and
diuretics
meso-oral

Altered
fat, carb
absorpti
on

Altered fat
storage

Altered
fat, carb
metaboli
sm

Famous and effective


herbal remedies
chemical classification

Caffeine

Garcinia cambogia
(Hydroxycitric Acid)

HCA
.lipid ox
appetite

Chitosan
fat
absorpt
ion

Green Tea

Hoodia
Appetite
suppress
ant

Benincasa hispida (winter


melon)
Appetite
suppressan
t
SSRI

Catha edulis (Yemenians


Esteba7a)

Amphetami
ne like
agent

Capsicum annuum

Sympathomim
etic

Cyamopsis tetragonolobus
(Guar GUM) = Glactomannan

Reduce
appetite by
delaying
gastric
emptying

Inhibition of nutrient
absorption

Hibiscus sabdariffa

Alpha-amylase
inhibitor
(weak)

Phaseolus vulgaris

Alpahaglucosidase
inhibitor

Triticum aestivum (whole


grains)

Alphaamylase
inhibitor

Panax ginseng

Anorexic
Pancreati
c lipase
inhibitor

Punica granatum ()

Pancreatic
lipase
inhibitor

Novel Pharmacological
treatment

Lorcaserin

HT 2c agonist-5

in 12 wk, without diet or 3%


exercise
Approved for BMI > 30

Tesofensine

Noradrenaline,
dopamine and 5HT reuptake
inhibitor

with higher dose (0.5mg) in 25 wks, 9%


with exer & diet

Zonisamide
Anticonvulsan
-t
D2 agonist
MAO inhibitor
(weak)

in 16 wks with exer and diet 5%

Rimonabant
(and taranabant)

inverse
agonist for
the
cannabinoid
receptor CB1

Withdrawn (sever depression and


suicidal) , illegal sales

Contrave (Bupropion +
naltrexone)
NA/ D2 RI->
endorphin release
(-ve feedback) so
add naltrexone

Empatic (Bupropion +
Zonisamide)

Bup offset depression


and sedation of zoni
and Zoni offset Bup
induced results

Qsymia (phentermine +
topiramate)
Low dose
amphetamine + anti
. topiramate convulsant

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