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  • Patho of Rectal Cancer

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    kururu_von
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    This document discusses risk factors and the development of colorectal cancer. It notes that age is the primary risk factor, and that mutations can inactivate tumor suppressor genes, activate proto-oncogenes into oncogenes, and impair DNA repair genes, allowing for the proliferation and accumulation of mutated cells. The final diagnosis discussed is adeno-rectal cancer.

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    This document discusses risk factors and the development of colorectal cancer. It notes that age is the primary risk factor, and that mutations can inactivate tumor suppressor genes, activate proto-oncogenes into oncogenes, and impair DNA repair genes, allowing for the proliferation and accumulation of mutated cells. The final diagnosis discussed is adeno-rectal cancer.

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    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
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    10 views2 pages

    Patho of Rectal Cancer

    Uploaded by

    kururu_von
    This document discusses risk factors and the development of colorectal cancer. It notes that age is the primary risk factor, and that mutations can inactivate tumor suppressor genes, activate proto-oncogenes into oncogenes, and impair DNA repair genes, allowing for the proliferation and accumulation of mutated cells. The final diagnosis discussed is adeno-rectal cancer.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
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    of 2

    Age: 65 ↑

    Cell mutation inactivates


    Risk Factors: tumor suppressor genes.

    Modifiable:
    Proliferations of cells
    1. Age.
    2. Gender.
    3. Polyps
    4. Diet. Mutation inactivates DNA
    5. Lifestyle
    repair genes
    factors
    6. Diabetes.
    7. Smoking
    Mutation of proto-oncogenes
    creates oncogenes.

    Non-Modifiable: Mutation inactivates several


    more tumor suppressor genes.
    1. Family
    history.
    2. Personal Cancer
    history.

    Signs/Symptoms:
    Final Diagnosis: Adeno-Rectal
    1. A change in bowel habits. Cancer
    2. Blood (bright either red or very dark) in the
    stool.
    3. Diarrhea, constipation, or feeling that the
    bowel does not empty completely.
    4. Stools that is narrower than usual.
    5. General abdominal discomfort (frequent gas
    pains, bloating, fullness, or cramps).
    6. Weight loss for no known reason.
    Feeling very tired.
    7. Vomiting.

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