Generic Name: Tetanus toxoid

Brand name: not specified

Classification: Vaccines, Antisera & Immunologicals

Indications: Prevention against tetanus in children and adult

Contraindications: Hypersensitivity, febrile illness and other acute infections, patient with
low immune response

Actual Dosage:

Adverse reactions: Local reactions (e.g., redness, swelling & pain with local
lymphadenopathy), tachycardia, hypotension, flushing, muscle pain, thrombocytopenia.

Mechanism of Action: Tetanus toxoid adsorbed induces active immunity to tetanus

antigen by stimulating the immune system to produce specific antitoxin.

Nursing Responsilbilities:
• Observe the 12 rights in giving the medication.
• Monitor vital signs.
• Allow the patient to lie down to prevent vomiting.
• Educate the patient to increase fluid intake to prevent dehydration.
• Educate patient that pain and tenderness in the injection site may occur.

Rationale: Prophylaxis for tetanus

Generic Name: Anti-Tetanus Serum

Brand Name: Not Specified

Classification: Vaccines, Antisera & Immunologicals

Indications: Prophylaxis and treatment of tetanus

Contraindications: Hypersensitivity, in patient with thrombocytopenia or coagulation

disorders

Actual Dosage:

Adverse Reactions: slight fever, nephritic syndrome, anaphylaxis angioedema, erythema,

pain, stiffness at injection site.

Mechanism of Action: Provide passive immunity to tetanus

Nursing Responsibilities:
• Observe 12 rights in giving the medication.
• Monitor vital signs.
• Monitor intake and output.
• Educate patient that pain and tenderness at injection site may occur.
• Educate patient to increase fluid intake.