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PATHOPHYSIOLOGY OF URINARY TRACT INFECTION

Causative organism

Ascent from the urethra and


in circulating blood (rare)

Clumps of bacteria may


be present

Inflammatory changes in
Contributing kidneys, ureters or bladder and
factors urethra.

Reflux Urine retention and Scarring of the kidney


stasis of urine in the parenchyma
bladder

If left untreated, kidney may become small, tissue


may be destroyed, and renal function could fail.

Interferes kidney function

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