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D’ADAMO

NAP PROFESSIONAL SERVICES


Deflect® (ABO Specific Lectin Blocker Formula)

Actions and Indications


The Deflect® formula provides a source of free blocking amino
sugars which bind and block lectins before they can attach to
the cells.
Since each blood type is succeptible to lectins with different
carbohydrate specificities, Dr. D’Adamo designed formulas to
block lectins by using mono and polysaccharides specific for
120 VeggieCaps per bottle. each blood type.
Suggested retail price: $34.95 The amino sugars in Deflect® encourage healthy bowel flora,
Typically, lectins can bind to many of the carbohydrate antigens although they do not provide a source of flora themselves.
found in the gut and immune system, causing a variety of health These same amino sugars are healthy enhancers of joint gliding
problems. This is usually accomplished by direct agglutination of surface and synovia as well.
the target cells. Lectins can occur in very common foods in the One way this repair mechanism works is by ‘prying off’
diet, and the majority is specific for the carbohydrates of the ABO lectins which have already adhered to cellular receptors, such
blood typing system. as insulin. Since insulin blockage by dietary lectins has been
linked to both insulin resistance and obesity, using Deflect® can
Clinical Indications help accelerate weight reduction in diet-compliant individuals
• Intestinal dysbiosis by speeding up the time it takes for the regeneration of new
• Bowel hyperpermiability insulin receptors or the ‘cleansing’ of the old ones.
• Immune dysfunction This can take upwards of one year in some individuals who
just follow the diet, and explains why some dieters do not see
• Food sensitivities and systemic inflammation weight loss in the early stages of the program. It is because of
• Metabolic Syndrome this ‘lectin-locking’ function that many other diets (which do
• Carbohydrate intolerant individuals who typically gain have accelerated weight loss in their early stages) cause their
weight on high carbohydrate diets. followers to lose muscle mass and fat -when what we want is
to lose only the fat. If the weight loss in the Blood Type Diet
In one study, the edible parts of 29 of 88 foods tested, including is occasionally slow, at least it is healthy: Losing only body fat
common salad ingredients, fresh fruits, roasted nuts, and processed means that a person’s weight loss can sometimes be only 50%
cereals were found to possess significant lectin-like activity as as rapid as other programs which are destroying muscle and fat.
assessed by hemagglutination and bacterial agglutination assays. The problem is that muscle is hard to get back, and any drop
Several common lectins, in particular, wheat germ agglutinin, are in muscle mass results in a lower metabolic rate, leaving the
known to bind to the insulin receptor and mimick the hormonal dieter more likely to gain back the weight, but this time only
effects of insulin on adipose tissue, an under-appreciated action in body fat.
which can account for why individuals on high carbohydrate diets Many lectins can amplify the effects of auto-immune disease,
often have difficulty contolling their weight. Thus, lectin blocking such as thyroiditis, rheumatoid arthritis, schleroderma,
is a safe and rational method for enhancing weight loss. fibromylagia and pemphigus. Research shows that some of the
In the words of one lectin researcher: lectins that can cause this may actually be manufactured by the
“Most lectins in our diet are resistant to breakdown during gut passage and
body itself (serum lectins). By acting as sacrificial molecules,
are bound and endocytosed by epithelial cells. These lectins are powerful
Deflect® can block this action.
exogenous growth factors for the small intestine, can induce dramatic Many people with ‘food sensitivities’ or ‘leaky gut’ have a
shifts in its bacterial flora and interfere with its hormone secretion. In phenomena called ‘active endocytosis’ where prior lectin
addition, lectins that are transported across the gut wall into the systemic damage results in an intestinal absorption surface that actively
circulation can modulate the body’s hormone balance, metabolism and scoops up macromolecules. Because these larger molecules are
health. Although these physiological effects are mediated or reinforced by very antigenic, they tend to increase local inflammation and
immune responses, they are primarily the result of the specific chemical thus increase the leaky gut. Again, by acting like ‘sacrifical
reactivity of lectins with cell surface receptors of the gut.” molecules’ Deflect® can block this, while also inhibiting bacterial
adhesion to the gut as well (bacteria use their own lectins to attach References
to the intestines) a secondary cause of leaky gut. The amino sugars 1. Basso, D. (1995). Living calcareous algae by a paleontological approach:
in Deflect® can also help prevent re-infection by H. pylori and 1. Freed DJ. British Medical Journal, 1999 Apr 17;318(7190):1023-4.
many gram-negative bacteria which cause bladder infections, by 2. Pusztai A. Dietary lectins are metabolic signals for the gut and modulate
flooding their own lectin receptors, thereby preventing adhesion, immune and hormone functions. Eur J Clin Nutr 1993 Oct;47(10):691-9
the first step needed for infection. 3. Irache JM, Durrer C, Duchene D, Ponchel Bioadhesion of lectin-latex
conjugates to rat intestinal mucosa. Pharm Res 1996 Nov;13(11):1716-9
The amino sugars in Deflect encourage healthy bowel flora,
®
4. Acarin L, Vela JM, Gonzalez B, Castellano B Demonstration of poly-
although they do not provide a source of flora themselves. These N-acetyl lactosamine residues in ameboid and ramified microglial cells
same amino sugars are healthy enhancers of joint gliding surface in rat brain by tomato lectin binding. J Histochem Cytochem 1994
and synovia as well. Aug;42(8):1033-41
5. Hussain N, Jani PU, Florence AT Enhanced oral uptake of tomato
Synergistic Products lectinconjugated nanoparticles in the rat. Pharm Res 1997 May;14(5):613-
• Redoxa, Quercetin (Leaky gut support in all types) 8
6. Chuang JS, Callaghan JM, Gleeson PA, Toh BH Diagnostic ELISA for
• Itaru’s Tea (Weight management in all types) parietal cell autoantibody using tomato lectin-purified gastric H+/K(+)-
• Polyflora O, Polyflora A, Polyflora B, Polyflora AB (Dysbiosis ATPase (proton pump). Autoimmunity 1992;12(1):1-7
in all types) 7. Tariq SM, Stevens M, Matthews S, Ridout S, Twiselton R, Hide DW
Cohort study of peanut and tree nut sensitisation by age of 4 years. BMJ
• Bromelain (Joint dysfunction in all types) 1996 Aug 31;313(7056):514-7
8. Gan RL[Peanut lectin-binding sites in gastric carcinoma and the adjacent
Dosage mucosa]. Chung-hua Ping Li Hsueh Tsa Chih 1990 Jun;19(2):109-11
• Weight management and anti-lectin support: 1-2 capsules
9. Lin M, et al Peanut lectin-binding sites and mucins in benign and
with meals malignant colorectal tissues associated with schistomatosis. Histol
• Other conditions: 1-2 capsule twice daily away from meals Histopathol. 1998 Oct;13(4):961-6.
10. Melato M, et al The lectin-binding sites for peanut agglutinin in
See Also invasive breast ductal carcinomas and their metastasis. Pathol Res Pract.
1998;194(9):603-8.
• Boyd’s Report of Lectin Specificity
11. Jordinson M, Playford RJ, Calam Effects of a panel of dietary lectins on
• Dietary lectins are metabolic signals for the gut and modulate cholecystokinin release in rats. Am J Physiol 1997 Oct;273(4 Pt 1):G946-
immune and hormone functions 50
12. Jordinson M, et al Soybean lectin stimulates pancreatic exocrine secretion
• Dietary lectins can induce in vitro release of IL-4 and IL-13 via CCK-A receptors in rats Am J Physiol. 1996 Apr;270(4 Pt 1):G653-9.
from human basophils 13. Mikkat U, Damm I, Schroder G, Schmidt K, Wirth C, Weber H, Jonas L
• Glycosylation Effect of the lectins wheat germ agglutinin (WGA) and Ulex europaeus
agglutinin
• Lectins, Mitogen and Blastogenic Effects 14. (UEA-I) on the alpha-amylase secretion of rat pancreas in vitro and in
• Lectins, Resistance to Degradation vivo. Pancreas 1998 May;16(4):529-38
15. Burks AW, et al Identification of peanut agglutinin and soybean trypsin
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Pt 6):411-6
Model: BT004O Model: BT004AB
* Manufactured by: Blood Type Diet * Manufactured by: Blood Type Diet

Model: BT004A Model: BT004B


* Manufactured by: Blood Type Diet * Manufactured by: Blood Type Diet

copyright © 2010, North American Pharmacal, Inc. All Rights Reserved. REV:051810:wst
These statements have not been evaluated by the FDA (U.S. Food & Drug Administration).
Our products are not intended to diagnose, cure or prevent any disease. If a condition persists, please contact your physician.
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