DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING

ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES

YOUR CLIENT
Tramadol Ultram Its exact mechanism INDICATION: Commonly To relieve client’s 1. Assess client for pain
of action is unknown reported side pain. and to hypersensitivity
50 mg/cap but similar Used to treat moderate to effects include to the drug.
q8 PRN morphine. Like moderately severe pain nausea, 2. Administer drug with or
morphine, tramadol and most types of constipation, without food. If patient
binds to receptors in dizziness, complains of nausea,
neuralgia, including
the brain (opioid headache, administer drug with
receptors) that are trigeminal neuralgia. It drowsiness, and food.
important for has been suggested that vomiting. Less 3. This drug may may
transmitting the tramadol could be commonly cause the client dizzy or
sensation of pain effective for alleviating reported side drowsy. To reduce
from throughout the symptoms of depression, effects include dizziness and
body to. anxiety, and phobias. itching, lightheadedness, assist
sweating, dry client in getting up
mouth, diarrhea, slowly when rising from
rash, visual a sitting or lying position.
disturbances, 4. Assess client’s pain
CONTRAINDICATION:
and vertigo. after 30 minutes to
evaluate client’s
Hypersensitivity to response to medication
Tramadol. as well as drug’s action.
 DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING
ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Methylerg Methergine A semisynthetic INDICATION: Hypertension For prevention 1. If I.V. administration is
onovine ergot alkaloid and a associated in and control of considered essential as a
maleate derivative of For routine management several cases postpartum lifesaving measure,
ergonovine and is after delivery of the with seizure hemorrhage. Methergine
0.2mg/1mL used for the placenta; postpartum (methylergonovine
IM prn and/or
prevention and atony and hemorrhage; maleate) should be given
headache.
control of subinvolution. Under full slowly over a period of no
postpartum and obstetric supervision, it Nausea and less than 60 seconds with
post-abortion may be given in the vomiting have careful monitoring of blood
hemorrhage. All of second stage of labor occurred pressure.
the alkaloids of ergot following delivery of the occasionally. 2. Caution should be
significantly increase anterior shoulder exercised in the presence
the motor activity of of sepsis,
the uterus. After obliterativevascular diseas
small doses CONTRAINDICATION: e,hepaticor renal 
contractions are involvement. Also use with
increased in force or Hypersensitivity to the caution during thesecond
frequency, or both, stage of labor . The
drug. Hypertension;
but are followed by a necessity for manual
toxemia; pregnancy;
normal degree of removal of a
relaxation. As the and hypersensitivity. retainedplacentashould
dose is increased, occur only rarely with
contractions become proper technique and
more forceful and adequate allowance of
prolonged, resting time for itsspontaneous
tonus is markedly separation.
increased, and
sustained
contracture can
result.

DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING

 ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Oxytocin Pitocin The uterine INDICATION: Shortness of To induce uterine 1. Assess client for pain
myometrium breath; closing contractions and to hypersensitivity
0.5 to 1 contains receptors Used to induce labor, during delivery. to the drug.
of the throat;
mL TIV specific to oxytocin strengthen labor
prn.
hives; swelling
Oxytocin stimulates contractions during 2. Administer drug exactly
of the lips,
contraction of childbirth, control bleeding as prescribed.
uterine smooth after childbirth, or to
face, or tongue;
muscle by induce an abortion.For rash; or fainting
increasing routine management after ; difficulty 3. Monitor for client’s
intracellular calcium delivery of the placenta; urinating;chest uterine contractions.
concentrations, thus postpartum atony and pain or
mimicking hemorrhage; irregular heart 4. Monitor for any adverse
contractions of subinvolution. beat; effects of the drug.
normal,
spontaneous labor
and transiently CONTRAINDICATION:
impeding uterine
blood flow. Hypersensitivity to the
Amplitude and drug. Use cautiously
duration of uterine
with eclampsia, herpes,
contractions are
increased, leading to prolapsed uterus, or
dilation and have a breech, placenta
effacement of the previa or any other
cervix. issues with the fetus or
umbilical cord.

DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING

ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
 YOUR CLIENT
Hyoscine N- Buscopan Active component in INDICATION: Constipation, To relieve bladder 1. Assess for
butylbromide buscopan is dry mouth, or intestinal hypersensitivity.
substance called Indicated for bladder, photophobia, spasms. 2. Tell your doctor your
10 mg/tab hyoscine. Hyoscin is genitor-urinary, or flushing, skin medical history,
PO, TID isolated from a intestinal spasms. especially of:
rash. Busopan
flower called glaucoma or other
may also cause
Hyosciamus niger. It eye problems, heart
belongs to group of urinary urgency disease, enlarged
CONTRAINDICATION:
alkaloids. Morphine and urinary prostate (males),
is maybe the most Hypersensivity to the retention. allergies, stomach or
popular alkaloid that drug. intestinal diseases.
is used in medicine. 3. Administer as
Buscopan is made ordered.
to relieve pain in 4. The usual maximum
gastrointestinal and number of tablets
urogenital tract. Its per day is 6.
targets are muscles Swallow tablets
in the walls of whole with a glass of
stomach and water.
intestines. Buscopan 5. If client is taking
helps those muscles antacids, administer
to relax. Mechanism at least one hour
of action of before antacids or
buscopan differents certain anti-diarrhea
from mechanism of drugs (e.g., kaolin-
classical analgesics pectin type).
or NSAILs.

DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING

ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Cefuroxime Ceftin A second generation INDICATION: Diarrhea, loose To prevent the  Assess client’s
cephalosporin with a stools, nausea, growth of bacteria hypersensitivity to the
750 mg/ 5ml broad antimicrobial The preoperative vomiting. that may cause drug.
TIV, 30 activity against both prophylactic infections during
 As with other
minutes to 1 Gram-positive and administration of labor and
hour before Gram-negative delivery. cephalosporins,
Cefuroxime for Injection reconstituted
operation organisms. It has
excellent in vitro USP and Dextrose Cefuroxime for Injection
activity against Injection USP may USP and Dextrose
staphylococcal prevent the growth of Injection USP tends to
strains, susceptible disease- darken depending on
streptococcal strains causing bacteria and storage conditions,
(other than thereby may reduce the within the stated
enterococci), N. recommendations.
incidence of certain
gonorrhoeae, H. However, product
influenzae and N. postoperative infections in
patients undergoing potency is not adversely
meningitidis.
surgical procedures (e.g., affected.
vaginal hysterectomy,  Use only if
delivery) that are prepared solution is
classified as clean- clear and free from
contaminated or
particulate matter.
potentially contaminated
 Monitor forany
adverse reactions.
procedures.

CONTRAINDICATION:

Hypersensivity to the
drug.
DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING
ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Metronidazole Flagyl Anti-protozoals. INDICATION: •CNS: To prevent  Assess client’s
Disrupts DNA and seizures, protozoal hypersensitivity to the
7.5 mg/kg protein synthesis in Protozoal or bacterial dizziness, infection for the drug.
q6hr PO (not susceptible infections; Amebicide in headache client.
 Administer with food
to exceed organisms. the management of
• GI: abdominal or milk to minimize GI
4g/day) Have bactericidal, or amebic dysentery.
amebicidal action.
pain, anorexia, irritation. Tablets may be
nausea, crushed for patients with
CONTRAINDICATION: difficulty swallowing.
diarrhea, dry
mouth, furry  May cause dizziness
Hypersensivity to the
tongue, or light-headedness.
drug.
glossitis, Caution patient or other
unpleasant activities requiring
alertness until response to
taste, vomiting
medication is known.
• Hematologic:
 Inform patient that
leukopenia
medication may cause an
• Skin: rashes, unpleasant metallic taste.
urticaria  Inform patient that
medication may cause
urine to turn dark.
 Advise patient to
consult health care
professional if no
improvement in a few
days or if signs and
symptoms of
superinfection (black furry
overgrowth on tongue;
loose or foul-smelling
stools develop).
 DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING
ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Cefuroxime Ceftin A second generation INDICATION: Diarrhea, loose To prevent the  Assess client’s
cephalosporin with a stools, nausea, growth of bacteria hypersensitivity to the
750 mg/ 5ml broad antimicrobial The preoperative vomiting. that may cause drug.
TIV, 30 activity against both prophylactic infections during
 As with other
minutes to 1 Gram-positive and administration of labor and
hour before Gram-negative delivery. cephalosporins,
Cefuroxime for Injection reconstituted
operation organisms. It has
excellent in vitro USP and Dextrose Cefuroxime for Injection
activity against Injection USP may USP and Dextrose
staphylococcal prevent the growth of Injection USP tends to
strains, susceptible disease- darken depending on
streptococcal strains causing bacteria and storage conditions,
(other than thereby may reduce the within the stated
enterococci), N. recommendations.
incidence of certain
gonorrhoeae, H. However, product
influenzae and N. postoperative infections in
patients undergoing potency is not adversely
meningitidis.
surgical procedures (e.g., affected.
vaginal hysterectomy,  Use only if
delivery) that are prepared solution is
classified as clean- clear and free from
particulate matter.
contaminated or
potentially contaminated
 Monitor forany
adverse reactions.
procedures.

CONTRAINDICATION:

Hypersensivity to the
drug.
DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING
 ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Diclofenac Cataflam A nonsteroidal anti- INDICATION: Hypertension, To treat pain and  Assess client’s
Sodium inflammatory drug abdominal pain, redness, swelling, hypersensitivity to the
(NSAID) that exhibits  Menstrual cramps and constipation, and heat drug.
100 mg/tab diarrhea,
anti-inflammatory, other types of short- (inflammation)  Assess for any
PO, OD analgesic, and term pain. dyspepsia, from delivery. contraindication such as
antipyretic activities in  For relief of the signs flatulence, gross heart disease.
animal models. The and symptoms of bleeding/perforat  Administer exactly
mechanism of action osteoarthritis. ion, heartburn, as prescribed.
of Diclofenac Sodium  For relief of the signs nausea, GI  Monitor for any
is related to and symptoms of ulcers. adverse effects of the
prostaglandin rheumatoid arthritis.
synthetase inhibition.
drug.

CONTRAINDICATION:

Hypersensivity to the
drug. Asthma, heart
disease, urticaria, or other
allergic-type reactions
after taking aspirin or
other NSAIDs.
 DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING
ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Cefuroxime Ceftin A second generation INDICATION: Diarrhea, loose To prevent the  Assess client’s
cephalosporin with a stools, nausea, growth of bacteria hypersensitivity to the
750 mg/ 5ml broad antimicrobial The preoperative vomiting. that may cause drug.
TIV, 30 activity against both prophylactic infections during
 As with other
minutes to 1 Gram-positive and administration of labor and
hour before Gram-negative delivery. cephalosporins,
Cefuroxime for Injection reconstituted
operation organisms. It has
excellent in vitro USP and Dextrose Cefuroxime for Injection
activity against Injection USP may USP and Dextrose
staphylococcal prevent the growth of Injection USP tends to
strains, susceptible disease- darken depending on
streptococcal strains causing bacteria and storage conditions,
(other than thereby may reduce the within the stated
enterococci), N. recommendations.
incidence of certain
gonorrhoeae, H. However, product
influenzae and N. postoperative infections in
patients undergoing potency is not adversely
meningitidis.
surgical procedures (e.g., affected.
vaginal hysterectomy,  Use only if
delivery) that are prepared solution is
classified as clean- clear and free from
particulate matter.
contaminated or
potentially contaminated
 Monitor forany
adverse reactions.
procedures.

CONTRAINDICATION:

Hypersensivity to the
drug.
DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING
 ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Ranitidine Zantac H2 antagonist and INDICATION: Confusion, To prevent acid  Assess client’s
an anti-ulcer agent. dizziness, indigestion of the hypersensitivity to the
20mg/mL TIV Inhibits the action of Treatment and prevention drowsiness, client. drug.
every 8 hours histamine at the H2 of heartburn, acid hallucinations,  Assess patient for
receptor site located indigestion, and sour headache, epigastric or abdominal pain
primarily in gastric stomach. arrhythmias. and frank or occult blood in
parietal cells, the stool, emesis, or gastric
resulting in aspirate
CONTRAINDICATION:
inhibition of gastric  Inform patient that it
acid secretion. In may cause drowsiness or
Hypersensivity to the
addition, ranitidine dizziness.
drug.
bismuth citrate has  Inform patient that
some antibacterial increased fluid and fiber
Use Cautiously in:
action against H. intake may minimize
pylori. constipation.
• Renal impairment
• Pregnancy, Lactation,  Advise patient to
After Delivery report onset of black, tarry
stools; fever, sore throat;
diarrhea; dizziness; rash;
confusion; or hallucinations
to health care professional
promptly.
 Inform patient that
medication may temporarily
cause stools and tongue to
appear gray black.
 DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING
ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Cefuroxime Ceftin A second generation INDICATION: Diarrhea, loose To prevent the  Assess client’s
cephalosporin with a stools, nausea, growth of hypersensitivity to the
750 mg/ 5ml broad antimicrobial The preoperative vomiting. bacteria that drug.
TIV, 30 activity against both prophylactic may cause
 As with other
minutes to 1 Gram-positive and administration of infections
hour before Gram-negative during labor cephalosporins,
Cefuroxime for Injection reconstituted Cefuroxime
operation organisms. It has and delivery.
excellent in vitro USP and Dextrose for Injection USP and
activity against Injection USP may Dextrose Injection USP
staphylococcal prevent the growth of tends to darken depending
strains, susceptible disease- on storage conditions,
streptococcal strains causing bacteria and within the stated
(other than thereby may reduce the recommendations.
enterococci), N. However, product potency
incidence of certain
gonorrhoeae, H. is not adversely affected.
influenzae and N. postoperative infections in
meningitidis. patients undergoing  Use only if prepared
surgical procedures (e.g., solution is clear and free
vaginal hysterectomy, from particulate matter.
delivery) that are  Monitor forany
classified as clean- adverse reactions.
contaminated or
potentially contaminated
procedures.

CONTRAINDICATION:

Hypersensivity to the
drug.
DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING
 ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON RESPONSIBILITIES
YOUR CLIENT
Keterolac Toradol Nonsteroidal anti- INDICATION: Drowsiness, To relieve  Assess client’s
inflammatory abnormal client’s pain. hypersensitivity to the drug.
30mg/amp agents, nonopioid Short term management of thinking,  Patients who have
1amp IM, prn analagesics. Inhibits pain (not to exceed 5 days dizziness, asthma, aspirin-induced
prostaglandin total for all routes euphoria, edema, allergy, and nasal polyps are at
synthesis, producing combined). pallor. increased risk for developing
peripherally hypersensitivity reactions.
mediated analgesia.  Assess pain (note type,
CONTRAINDICATION:
Also has antipyretic location, and intensity) prior to
and anti- and 1-2 hr following
Hypersensivity to the
inflammatory administration.
drug.
properties. - Cross-sensitivity with  Ketorolac therapy should
other NSAIDs may exist always be given initially by the
IM or IV route. Oral therapy
¨Pre- or perioperative use
should be used only as a
- Known alcohol
continuation of parenteral
intolerance.
therapy.
Use cautiously in:  Caution patient to avoid
concurrent use of alcohol,
1) History of GI bleeding
aspirin, NSAIDs,
2) Renal impair-ment
acetaminophen, or other OTC
(dosage reduction may be
medications without consulting
required)
health care professional.
3) Cardiovascular disease.
 Advise patient to consult
if rash, itching, visual
disturbances, tinnitus, weight
gain, edema, black stools,
persistent headche, or
influenza-like syndromes occur.
 DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING RESPONSIBILITIES
ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON
YOUR CLIENT
Cefuroxime Ceftin A second generation INDICATION: Diarrhea, loose To prevent the  Assess client’s
cephalosporin with a stools, nausea, growth of hypersensitivity to the drug.
750 mg/ 5ml broad antimicrobial The preoperative vomiting. bacteria that  As with other
TIV, 30 activity against both prophylactic may cause
cephalosporins,
minutes to 1 Gram-positive and administration of infections
hour before Gram-negative during labor reconstituted Cefuroxime
Cefuroxime for Injection for Injection USP and
operation organisms. It has and delivery.
excellent in vitro USP and Dextrose Dextrose Injection USP
activity against Injection USP may tends to darken depending
staphylococcal prevent the growth of on storage conditions,
strains, susceptible disease- within the stated
streptococcal strains causing bacteria and recommendations.
(other than thereby may reduce the However, product potency
enterococci), N. is not adversely affected.
incidence of certain
gonorrhoeae, H.
postoperative infections in  Use only if prepared
influenzae and N.
meningitidis. patients undergoing solution is clear and free
surgical procedures (e.g., from particulate matter.
vaginal hysterectomy,  Monitor forany
delivery) that are adverse reactions.
classified as clean-
contaminated or
potentially contaminated
procedures.

CONTRAINDICATION:

Hypersensivity to the
drug.
DRUG BRAND PHARMACOLOGIC INDICATIONS AND ADVERSE DESIRED NURSING RESPONSIBILITIES
 ORDER NAME ACTION CONTRAINDICATIONS REACTIONS ACTION ON
YOUR CLIENT
nalbuphine Nubain INDICATION: Sweaty, clammy, To relieve  Assess client’s
nausea, client’s pain. hypersensitivity to the drug.
mg IM, prn Indicated for the relief of vomiting,
moderate to severe pain. dizziness,
NUBAIN can also be used as vertigo.
a supplement to balanced
anesthesia, for preoperative
and postoperative analgesia,
and for obstetrical analgesia
during labor and delivery.

CONTRAINDICATION:

Hypersensivity to the
drug.