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Fibrilin are microfibrils microprotein dissolve in ground subs Elastin lay down in fibers See ppt.. Formation: elastogenesis Fibroblast secrete microfibrils and tropoeslastin Cartilage cells secrete also microfibrils and tropoelastin

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Reticular: made of collagen III 2 types of fiber collagen and elastin (author) Finer than reticular Few in most connective tissue, form the connective tissue in bone marrow and comprise af lamina reticularis??? Precursor: secreted by fibroblast reticular cells secrete precursor of collagen fibers

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Cells 2 types resident and visiting Fibroblast adipose reticular arise from mesenchymal cell/stem cell Stem cell in cartilage and bone and muscles All cell derived from fertilized ovum or zygote undergo simple mitosis.. can differentiate any cell type of body all cells are pluripotential cell(can t form lil membrane but can form body cells, origin of all cells in the body).. during differentiation 1 grp cell form fetal membrane, 1 grp to differentiate any cell type of the body.. stem cell are common in embryo (mesenchymal) resident cells: 1. Fibrolast 2. Adipose tissue 3. Reticular tissue 4. Mast cell 5. Resident macrophage visiting cells: 1. Inflammatory macrophage 2. Plasma cell 3. Leukocytes or white blood cell

connective tissue: mast cell: resident cells larhe=ge, ovate cell, not distinguishabkle nucelues: centrally located; sphericval

secretory granules: vary in sze and shape; all membrane bpound; -3-08 um in dm; variable in shape; metachromatic; dark purple with toluidine blue; not seen in H&E; contain histamine and heparin; sparse in most resident cells: mast cell vs. basophil both have cytoplasmic granules both arise in bone marrow but from diff progenitor cell mast cells settle permanently in connective tissue and not circulate in blood basophils are smaller but more mobile basophils have shorter life span mast cells live from weeks to months mast cells can divide; basophil cannot

macrophages different from monocytes phagocytes that serve as effectro cell of mononuclear phagocyhte sytem FNX:  Heterophagy  Autophagy  Participates in body s immune system by presenting antigen to lymphocytes Present in all body not just in connective tissue Some have other names: o Pulmonary alveolar marphage (lung) In connective tissue, 1. Resident- inhabits in a given site -not as immunpologically