Scribd Logo
Upload

Welcome to Scribd!

  • Den Ti No Genesis

    Uploaded by

    Munir Ahmad
    31 views20 pages
    Dentinogenesis is the formation of dentin, which occurs prior to amelogenesis or enamel formation. Odontoblasts are integral parts of both dentin and pulp - they form the dentin matrix and help convey sensory information via neurons. Soon after the first layer of mantle dentin is deposited, odontoblasts secrete enzymes that digest the basement membrane and allow direct contact between the enamel and dentin matrices, forming a strong bond. Dentinogenesis and enamel formation begin after the crown shape is established in the soft tissue during the bell stage.

    Original Description:

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Dentinogenesis is the formation of dentin, which occurs prior to amelogenesis or enamel formation. Odontoblasts are integral parts of both dentin and pulp - they form the dentin matrix and help convey sensory information via neurons. Soon after the first layer of mantle dentin is deposited, odontoblasts secrete enzymes that digest the basement membrane and allow direct contact between the enamel and dentin matrices, forming a strong bond. Dentinogenesis and enamel formation begin after the crown shape is established in the soft tissue during the bell stage.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    31 views20 pages

    Den Ti No Genesis

    Uploaded by

    Munir Ahmad
    Dentinogenesis is the formation of dentin, which occurs prior to amelogenesis or enamel formation. Odontoblasts are integral parts of both dentin and pulp - they form the dentin matrix and help convey sensory information via neurons. Soon after the first layer of mantle dentin is deposited, odontoblasts secrete enzymes that digest the basement membrane and allow direct contact between the enamel and dentin matrices, forming a strong bond. Dentinogenesis and enamel formation begin after the crown shape is established in the soft tissue during the bell stage.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 20

    Dentinogenesis

    Professor Dr Maha M.F Mounir

    Dentin & Pulp


    Odontoblasts are an integral part of both dentin & pulp

    Dentin is a vital tissue containing cell processes of odontoblasts & neurons. Odontoblasts form dentin matrix, & neurons convey sensory information

    Dentinogenesis occurs prior to amelogenesis


    Soon after the deposition of the first layer of dentin (mantle dentin), odontoblasts express MMPs to digest the basement membrane to allow E & D matrices & their respective mineral phases to come onto direct contact a strong mechanical bond is formed between E & D

    Bell stage-establishing coronal form


    Secretion & mineralization of dentin & enamel matrices begins only after the shape of crown has been determined in soft tissue Secretion & mineralization of dentin precedes enamel formation

    Dentinogenesis

    Dentinogenesis
    Preodontoblast elongates & forms the odontoblastic process. The nuclei occupies the basal portion of the cell & organelles are located at apical end,Polarity

    ODONTOBLATS
    Consists of a cell body + an odontoblastic process ( that branches laterally & terminally)
    Function: secretion, distribution & removal of matrix components+ mineralization of dentin

    Mantle Dentin
    First formed layer of dentin. It contains thick collagen fibers that lie perpendicular to the ADJ ( fibers of circumpulpal dentin are parallel approximately to ADJ & are finer)

    Von Korffs Fibers


    Are the first secreted collagen fibers (dentin matrix protein) that may pass between differentiating odontoblasts & extend towards basal lamina where they end in a fan shaped arrangement (argyrophilic= take silver stain) Consists of type I + type III collagen

    Predentin
    Is the un-mineralized dentin matrix

    Predentin

    Dentin Matrix proteins


    Are secreted externally via transport vesicles

    incremental deposition of enamel & dentin

    Forming dentin in crown area

    Dentine mineralization
    Small mineral crystals in:1.Matrix vesicles
    2.nucleated in spaced within collagen fibrils ( globular & linear mineralization)

    Incremental deposition of dentin


    Incremental lines of Von Ebner Neo-natal line

    Thank you

    You might also like