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Drug

Generic name: Biperiden

Classification
Antiparkinsonian

Dosage
Adult:  Parkinsonism – 2mg PO tid to qid; individualize dosage, maximum, 16 mg/day (8 tablets0.  Drug-induced extrapyramidal disorder: 2mg PO daily to tid. Pediatric patients:  Safety and efficacy not established. Geriatric patients:  Strict dosage regulation may be necessary; patient older than 60 yr often develop increased sensitivity to the CNS effects of anticholinergic drugs.

Mechanism Of Action
Anticholinergic acticity int the CNS that is believed to help normalize the hypothesized inbalance of cholinergic and dopaminergic neurotransmission in the basal ganglia in the brain of a parkinsonism patient. Reduces severity of rigidity, and to a lesser extent, akinesia and tremor characterizing parkinsonism; less effective overall than levodopa; peripheral anticholinergic effects suppress secondary symptoms of parkinsonism, such as drooling.

Adverse Reaction

Contraindication

Indication

Teaching Points
 Take this drug exactly as prescribed.  Avoid the use of alcohol, sedative, and over – the counter drugs (can cause dangerous effects).  You may experience these side effects: drowsiness, dizziness, confusion, blurred vision (avoid driving or engaging in activities that require alertness and visual acuity); nausea (eat frequent small meals); dry mouth ( suck sugarless lozenges or ice chips); painful or difficult urination (empty bladder immediately before each dose); constipation (maintain adequate fluid intake and exercise regularly); use caution in hot weather (you are susceptible to heat prostration).  Report difficult or painful urination; constipation; rapid or pounding heartbeat; confusion, eye pain, or rash.

Brand name: Akineton

Pregnancy category: C

 CNS:  Contraindicated with  Adjunct in the disorientation, hypersensitivity to therapy of confusion, benztropine; parkinsonism (post nervousness, glaucoma, especially encephalitic, lightangle –closure arteriosclerotic, headedness, glaucoma; pyloric or and idiopathic dizziness duodenal type) obstruction,  CV:  Relief for stenosing peptic tachycardia, symptoms of ulcers, achalasia palpitations, extrapyramidal (mega – esophagus); hypotension, disorders that prostatic orthostatic accompany hypertrophy or hypotension phenothiazine bladder neck therapy.  Dermatologic: obstractions; rash, urticaria myasthenia gravis.  EENT: blurred  Use cautiously with vision, tachycardia, cardiac mydriasis, angle arrhythmias, closure hypertension, glaucoma hypotension, hepatic  GI: dry mouth, or renal impairment, constipation alcoholism, chronic  GU: urinary illness, people who retension, work in a hot urinary environment; hot hecitancy, weather; lactation; dysuria Alzheimer’s disease,  Others: pregnancy. flushing, decreased sweating, elevated temp.

mg tablets (these tablets contain tartrazine).2-. including those parts of the brain involved with wakefulness and emesis. anorexia. constipation (medication may be available to help). weakness. antipsychotics block postsynaptic dopamine receptors in the brain. urinary retention (empty your bladder before taking the drug). yellowing of the skin or eyes. Pediatric 3 -12 yr or 15 – 40 kg: Initial dosage.  You may experience these side effects: dry mouth (sucking sugarless lozenges may help). however.0 mg bid – tid). depress the RAS. fever.and 10. tardive dyskinesia. CNS infection. all adverse effects associated with phenothiazines therapy should be kept in mind when haloperidol is used.  Avoid prolonged exposure to sun. nausea. allergy to aspirin if giving the 1-. respiratory disorder. and use precautions against heatstroke in hot weather. severe hypotension or hypertension. akathisia. subcortical brain damage. 3 – 5 mg bid – tid PO (more resistant patient).  Control of tics and vocalizations in Tourette syndrome in adults and children. nasal congestion. Adults: Oral – 0. unusual bleeding or bruising. coma or severe CNS depression.Drug Generic name: Haloperidol Classification Antipsychotic Dopaminergic blocker Dosage Full clinical effects may require 6 wk – 6 mo of therapy. debilitated and geriatric patients. Brand name: Haldol Decanoate Pregnancy category: C . Indication  Management of manifestations of psychotic disorders. breast cancer.  Haloperidol decanoate: prolonged parenteral therapy of chronic schizophrenia. Mechanism Of Action Mechanism not fully understood. Use cautiously with pregnancy. Contraindication Contraindicated with hypersensitivity to typical antipsychotics. Adverse Reaction Not all effects have been reported with haloperidol. pseudoparkinson ism.5 – 2. and increase dosage more gradually than in younger pts. 0. blood dyscrasia.  Short – term treatment of hyperactive children with excessive motor activity. and patients with a history of adverse reactions to neuroleptic drugs may require lower dosage.  Avoid driving or engaging in other dangerous activities if dizziness or drowsiness or vision changes occur. explosive hyperexcitability that cannot be attributed to immediate provocation. children younger than 12 yr. Parkinson’s disease. chemically resembles the phenothiazines.5.5 mg/day (25 – 50 mcg/kg/day) PO Geriatric pts: Use lower doses (0. IM – 2 – 5 mg (up to 10 – 30 mg) q60 min or q4 – 8 hr MI. extrapyramidal syndrome – dystonia.  Maintain fluid intake. fever. vomiting. circulatory collapse. impaired vision. liver damage. pale stool. salivation. lactation. pallor  CNS: drowsiness. because haloperidol has certain pharmacologic similarities to the phenothiazine class of antipsychotic drugs. cerebral arteriosclerosis. tremors. Teaching Points  Take this drug exactly as prescribed. coronary disease. mood lability. or use a sunscreen or covering garments. Children.  Report sore throat. bone marrow depression. epilepsy or history of epilepsy.  Autonomic: dry mouth.5 – 2 mg bid – tid PO (moderate s/s).  Behavioral problems in children with combative. rash. dark – colored urine (pink or reddish brown urine is to be expected).

liver  CV: damage. yellowing of the skin and eyes. tachycardia  Use cautiously with  EENT: nasal respiratory congestion.  Control of nausea and vomiting and intractable hiccups. Unusual bleeding or bruising. and alpha – adrenergic blocking. peptic ulcer. hypertrophy. fever. prostate in females. breast galactorrhea. Adults:  Excessive anxiety. glaucoma.  GI: dry children with mouth. coronary ortostatic arteriosclerosis. sensitivity to the sun (avoid prolonged sun exposure. bone syndromes. anorexia.Drug Generic name: Chlorpromazine hydrochloride Classification Antiemetic Antipsychotic Anxiolytic Dopaminergic blocker Phenothiazine Dosage Full clinical antipsychotic effects may require 6 wk to 6 mo of therapy. photophobia. impaired vision. severe hypotension hypertension. Avoid over – the. which increases drowsiness). neuroleptic circulatory collapse. cerebral or hypertension. malignant sub cortical brain syndrome. peptic  Endocrine: ulcer or history of lactation. use caution climbing stairs. breast decrease renal engorgement function.  Learn how to dilute oral drug concentrate or how to use rectal suppository.  You may experience these side effect: drowsiness (avoid driving or operating dangerous machinery. Teaching Points  Take drug exactly as prescribed. Geriatric pts: Start dosage at one-fourth to one-third that given in younger adults and increase more gradually. or hypertension. Brand name: Thorazine Pregnancy category: C  Contraindicated with  CNS: drowsiness.  Do not get oral concentrate on your skin or cloths. allergy to insomnia. pale stools. Mechanism Of Action Mechanism not fully understood.  Severe behavioral problems in children. marrow depression.  Therapy for combativeness. weakness. nausea. dark urine. and do not over exercise in a hot climate. pink or reddish brown urine (expected effect).  Use caution in hot weather risk of heat stroke. rash. comatose or severely extrapyramidal depress states. epilepsy or history blurred vision of epilepsy. faintness. cancer. tremors. damage. Parkinson’s disease. antihistaminic (H1).  Acute intermittent porphyria therapy. dizziness (change position slowly. agitation in psychiatric pt: 25mg IM. SIADH tyrotoxicosis.  Adjunct treatment of tetanus. salivation. keep up fluid intake.  Relief of preoperative restlessness and apprehension. hyperactivity. control of manic phase of manic depressive illness. disorders. contact dermatitis can occur. Adverse Reaction Contraindication Indication  Management of manifestations of psychotic disorders. anticholinergic. constipation . avoid alcohol. usually transient). chicken pox. vomiting. wear protective garments or use sunscreens). hypotension. Pediatric pts: Generally not used in children younger than 6 mo. may repeat in 1 hr. chlorpromazine.counter drugs and alcohol unless you have consulted your health care provider.  Intractable hiccups: 25 – 50mg PO tid – qid. depress those parts of the brain involved in wakefulness and emesis.  Report sore throat. vertigo. antipsychotic drug block postsynaptic dopamine receptors in the brain.

tremor. bone fluphenazine syndrome. prostatic mental retardation. anaphylactoid reaction. laryngeal edema.neurole coma or severe CNS forms. damage. fluphenazine disturbance. lactation.  Fluphenazine brest pregnancy. use a sunscreen or cover skin if exposure is unavoidable.  Maintain fluid intake. tremors. depress the RAS. cerebral schizophrenics) pulmonary edema arteriosclerosis.  Avoid prolonged exposure to sun. and alpha – adrenergic blocking activity also may contribute to some of its therapeutic (and adverse) actions. weakness. rash. CNS infection. unusual bleeding or bruising. extrapyramidal symptoms. tartrazine. patient with leucopenia. Mechanism Of Action Mechanism not fully understood: Antipsychotic drugs block postsynaptic dopamine receptors in the brain. determine subsequent doses and dosage interval based on patient response. Dose should not exceed 100mg.5mg increments. weakness. refractory disease. hypertrophy. children  Hypersensitivity: younger than 12 yrs. parenteral dosage akathisias. Pediatric pts: generally not recommended for children younger than 12 yr. pneumonia”). ptic malignants depression. pale stool. Geriatric pst: Oral – initial oral dose is 1 – 2. . Adverse Reaction Contraindication Indication Teaching Points  Take drug exactly as prescribed. If doses above 50 mg are needed. Brand name: Apo – Fluphenazine Pregnancy category: C  CNS: drowsiness. including the part of the brain involved with wakefulness and emesis. glaucoma. prolonged hypoglycemia. increase cautiously in 12.5mg/day. the longer acting ism). (pseudoparkinson phenothiazines. dystonias. who require  Endocrine: coronary disease. decanoate: engorgement in  Use catiously with management of female respiratory disorder behavioral  Hematologic: (“silent complications in eosinophilia.Drug Generic name: Fluphenazine decanoate Classification Antipsychotic Dopaminergic blocker Phenothiazine Dosage IM or subcutaneous: initial dose. Parkinson’s management of arrest. antihistaminic (H1). and use precautions against heatstroke in hot weather. 12. enanthate and autonomic blood dyscrasia. yellowing of skin or eyes. decanoate. fever. dark urine (pink or reddish brown urine is expected). impaired vision. liver patients (chronic arrhythmias.  Contraindicated with  Management of extrapyramidal hypersensitivity to manifestations of syndrome fluphenazine. or aspirin. urticaria. or vision changes occur.  Avoid driving or engaging in other dangerous activities if drowsiness.  Report sore throat.5 – 25 mg IM or subcutaneous. circulatory collapse. aplastic anemia. or hypertension. severe hypotension parenteral therapy. subcortical brain indicated for  CV: cardiac damage. anticholinergic. SIADH. hemolytic anemia lactation. other psychotic disorder. marrow depression.

pneumonitis or pneumonia Contraindication Indication Teaching Points  Take drug with food as prescribed. Keep all appointments for checkups. these could cause dangerous effects. hepatic. you should consult your physician. hepatitis. massive hepatic cellular necrosis with total loss of intact liver tissue  GU: urinary frequency. Drug is chemically related to the TCAs. acute urinary retention. Pediatric patients younger than 6 yrs: optimal daily dose. including schizoaffective illness. depression. SIADH. with bipolar 1 disorder (Equetro)  Unlabeled use: certain psychiatric disorders. or renal damage. vomiting. do not cut. such as 1 tsp of applesauce. if you wish to become pregnant.  Avoid alcohol. Brand name: Tegretol Pregnancy category: D  Contraindicated with  Refractory seizure hypersensitivity to disorders: partial carbamazepine or seizures with TCAs. lactation. crush or chew them.Drug Generic name: Carbamezepine Classification Antiepileptic Dosage Individualized dosage. side effects.  Do not discontinue drug abruptly or change dosage. until best response is achieved. pruritic and erythematous rashes  GI: nausea. to monitor your response to this drug.  Use contraceptives at all times. may cause confusion. darkened urine. dizziness.000 mg/day in pts 12-15yrs. sleepinducing. except on the advice of your physician. GI upset. chills  CV: heart failure. tonic-clonic (grand pregnancy. abdominal pain. or over-the-counter drugs.  You may experience: drowsiness. antiepileptic activity may be related to its ability to inhibit polysynaptic response and block post-titanic potentiation. generalized MAOIs.200 mg PO bid on the first day. history of complex symptoms bone marrow (psychomotor. swallow extended-release tablets whole. unsteadiness. mal) seizure. dyspnea. yellowing of the skin and eyes.  Report bruising.  Arrange for frequent checkups. Geriatric patient: use caution. including blood tests. temporal lobe concomitant use of epilepsy). Epilepsy: initial dose. drowsiness. a low initial dosage with gradual increase is advised. fever. CV complications  Dermatologic: Stevens-Johnsons syndrome. such as history of cardiac. less than 35mg/kg/day. If using Equetro capsule. excessive sedation. agitation Mechanism Of Action Mechanism of action not understood. resistant schizophrenia . Do not exceed 1. Pediatric patients older than 12yr: Use adult dosage. increase gradually by up to 200 mg/day in divided doses every 6-8hr. renal failure  Respiratory: pulmonary hypersensitivity characterized by fever. psychiatric  Treatment of acute patients (may manic and mixed activate latent episodes associated psychosis). hematologic reaction Reserved to patients to any drug unresponsive to other Iincreased risk of agents with seizures severe hematologic difficult to control or toxicity). blurred vision. Adverse Reaction  CNS: dizziness. mixed seizure patients or  Use cautiously with other partial or history of adverse generalized seizures. they may be opened and contents sprinkled over soft food. 1. unsual bleeding.200mg/day in pts older than 15yr. glaucoma who are experiencing or increased IOP.

decreases intraneuronal content of second messengers and may thereby selectively modulate the responsiveness of hyperactive neurons that might contribute to the manic state. Mechanism Of Action Mechanism is not known. and 1. If you wish to become pregnant or believe that you have become pregnant. infection usual urine with fever. levels: dehydration. but not serotonin. GI upset (eat frequent small meals). lack of coordination or muscular weakness. tartrazine.Mild thirst suicidal or impulsive . tremor. consult your health care provider. hypothyroidism (doses of 600-900 mg/day).5 mEq/l. maintain adequate fluid intake (at least 2.  Arrange for frequent checkups to get the most benefits with the least toxicity.000 md/day. mild thirst.Drug Generic name: Lithium carbonate Classification Antimanic drug Dosage Individualized dosage according to serum level and clinical response. Pediatric patient Safety and efficacy for children younger than 12 yr not established. sodium Therapeutic depletion. Adults  Acute mania:600mg PO tid or 900mg slow-release from PO bid to produce effective serum levels between 1 and 1. maintenance therapy to prevent or diminish frequency and intensity of subsequent manic episode. Duralith Pregnancy category: D Reactions are  Contraindicated with related to serum hypersensitivity to lithium levels. notify your health care provider if severe). serum levels of 0.Drowsiness  Use cautiously with . Unlabeled use: improvement of neutrophil counts in patient cancer chemotherapyinduced neutropenia and in children with chronic neutropenia and HIV patients on zidovudine therapy (dose of 300-1.Greater than patients.GI upset and diarrhea.5 quarts/day). inhibits release of norepinephrine and dopamine. lactation . from stimulated neurons.6-1.5 mEq/l. dizziness (avoid driving or performing tasks that require alertness). prophylaxis of cluster headache and cyclic migraine headache.Dizziness protracted sweating . severe therapeutic debilitation.5 and 1 mEq/l). do not chew or crush.2 inhibitors. pregnancy. Brand name: Carbolith. fine hand tremor (may persist throughout therapy.  Report diarrhea or fever. alters sodium transport in nerve and muscle cells. vomiting.  Discontinue drug and notify your health care provider if toxicity occurs – diarrhea. hyponatremia therapeutic levels increases lithium for maintainance retention). use ACE are 0.2 mEq/l. . volume . after meals or with food or milk. (Toxic lithium significant renal or levels are close to CV disease. drowsiness. patients levels in acute on diuretic (lithium mania range decreases sodium between 1 and reabsorption. Swallow sustained –or controlledrelease tablets whole. Geriatric patients and pts with renal impairment Reduced dosage may be needed. ataxia.  You may experience these side effects: drowsiness. mEq/l. Adverse Reaction Contraindication Indication Treatment of manic episodes of bipolar disorder.6-1. slightly increases intraneuronal stores of atecholamines.  Longer term use: 300mg PO tid-qid to produce a serum level of 0.Fine hand tremor . Teaching Points  Take drug exactly as prescribed. greater than usual urine volume.  Eat a normal diet with normal salt intake. treatment of SIADH.  Use contraceptives to avoid pregnancy.

suicidal thoughts. if a large dose is needed. Brand name: Luvox Pregnancy category: C  CNS: headache. 25mg PO at bedtime. Increase 50mg increments at 4-7 day intervals. acne. alopecia. rash. gingivitis  GU: sexual dysfunction. form of treatment should be reconsidered. abnormal gait. renal function. CV sweating. cystitis. weight loss (eat frequent small meals). light Use cautiously with headedness. insomnia (avoid driving or performing hazardous tasks). dyspnea. delivery. 100300 mg/day. hypersensitivity to drowsiness.  Do not stop taking this drug abruptly. blocks uptake of serotonin with weak effect on norepinephrine. the dose may be divided but take the largest dose at bedtime. panic disorder Teaching Points  Take this drug at bedtime. vomiting. histaminergic.  Report rash. impotence. vomiting. Do not cut. vaginitis  Respiratory: URIs. Mechanism Of Action Selectively inhibits CNS neuronal uptake of serotonin. fluvoxamine. little affinity for muscarinic. cough. CR capsules 100-300 mg/day PO. Divided dose over 100mg/day. contact pregnancy. Pediatric patients 8-17 yr: Initially.Drug Generic name: Fluvoxamine maleate Classification SSRI Dosage Adult: Initially. and alpha1. 50mg PO at bedtime. diarrhea.  Contraindicated nervousness. mania. seizures. frequency. labor and pruritus. with insomnia. taste changes.  You may experience these side effects: dizziness. sexual dysfunction (reversible). seizures.  Dermatologic: ECT therapy. disease. give larger dose at bedtime. Usual range. severe weight loss. it should be discontinued slowly. Increase dosage by 25 mg/day every 4-7 days to achieve desired effect. bulimia nervosa. anxiety. – adrenergic receptors. mania. seizure. dry mouth. Adverse Reaction Contraindication Indication  Treatment of OCD  Treatment of social anxiety disorder (CR capsules)  Unlabeled use: treatment of depression. adjust more slowly. dermatitis  GI: nausea. If symptoms do not improve within 1-2 wk. suicidal tendencies. Geriatric patients or patients with hepatic impairment: Give a reduced dose (25mg PO at bedtime). flatulence. bronchitis . tremor. constipation. crush or chew controlledrelease capsules. pharyngitis. sedation. nausea. drowsiness. nervousness. impaired hepatic or agitation. gastroenteritis. lactation dizziness. anorexia.

histaminergic. increased depression. gastroenteritis  GU: painful menstruation. Geriatric patients or patients with hepatic impairment:  Give a lower or less frequent dose.  Dilute concentrate immediately before use in 4 ounces of water. It may take 4-6 wks to see any improvement. perform frequent mouth care).  PMDD: 50mg/day PO daily or just during luteal phase of menstrual cycle  Social anxiety disorder: 25mg/day PO Pediatric patients:  OCD: 6-12 yr: 25mg PO once daily. and alpha1 – adrenergic or dopaminergic receptors. may be increased up to 200mg/day. impaired hepatic or insomnia. morning or evening. Mechanism Of Action Acts as an antidepressant by inhibiting CNS neuronal uptake of serotonin. seizures. mania. do not exceed the prescribed dose. Use response as dosage guide. rhinitis. lemonade. pregnancy. nervousness. hot flashes. lactation. vomiting. Brand name: Zoloft Pregnancy category: C  CNS: headache. fatigue  Dermatologic: sweating.  You may experience these side effects: dizziness.  Use cautiously with dizziness.  Report rash. nausea. drowsiness. at the same time. hypersensitivity to drowsiness. or orange juice only. vomiting (eat frequent small meals). blocks uptake of serotonin with little effect on norepinephrine.  Contraindicated with nervousness. diarrhea. 50mg daily. renal function.  Panic disorder and PTSD: 25mg PO daily. Adverse Reaction Contraindication Indication  Treatment of major depressive disorder  Treatment of OCD  Treatment of panic disorder with or without agoraphobia  Treatment of PTSD. 13-17 yr: 50mg PO once daily. thirst . tremor. back pain. ginger ale. dry mouth. thought of suicide. dry mouth suck sugarless lozenges. muscarinic. edema. excessive sweating (monitor temperature. sertraline anxiety. difficulty breathing. pruritus  GI: nausea. long-term use to prevent relapse and sustain symptom improvement  Treatment of PMDD  Treatment of social anxiety disorder(social phobia)  Unlabeled uses: Nocturnal enuresis. lemon lime soda. dyspnea  Others: hot flashes. insomnia (avoid driving or performing hazardous tasks). sexual dysfunction  Respiratory: URIs. avoid over heating). morning or evening. fever. vision changes.Drug Generic name: Sertraline hydrochloride Classification Antidepressant SSRI Dosage Adults:  Major depressive disorder and OCD: administer once a day. rash.  Consult your health care provider if you think that you are pregnant or wish to become pregnant. cholestatic pruritus Teaching Points  Take the drug once a day.

or over-the-counter drugs and grapefruit juice. abnormal posture. nervousness. altered taste and smell. dizziness. confusion. Indication  Management of anxiety disorders or short term relief of symptoms of anxiety  Unlabeled use: decreasing the symptoms (aches. cramps. GI upset (eat frequent small meals).  Avoid the use of alcohol. Adverse Reaction  CNS: dizziness. dream disturbance.5 mg bid). urinary hesitancy  Respiratory: hyperventilation shortness of breath. light-headedness (avoid driving or operating complex machinery). dry mouth. involuntary movements  CV: nonspecific chest pain. will stop when the drug is discontinued). vomiting. dreams. constipation  GU: urinary frequency. lacks anti-seizure. difficulty concentrating or sleeping. clamminess. 15 mg/day PO (7. light headedness. binds serotonin receptors. mild renal or hepatic impairment. marked liver or renal impairment. but the clinical significance is unclear. Mechanism Of Action Mechanism of action not known. fatigue. or muscle relaxant properties. Increase dosage 5mg/day at intervals of 2-3 days to achieve optimal therapeutic response. Pediatric patients: Safety and efficacy for patients younger than 18 yr not established. excitement (reversible. Brand name: Buspar Pregnancy category: B . Do not exceed 60mg/day. headache. diarrhea. lactation  Use cautiously with pregnancy. chest congestion  Others: musculoskeletal aches and pain. yellowing of the skin or eyes. sore throat Contraindication  Contraindicated with hypersensitivity to buspirone. flatulence. pains.  Report abnormal involuntary movements of facial or neck muscles. sleepinducing. excitement. Divided doses of 20-30 mg/day have been used.  You may experience these side effects: drowsiness. these could cause dangerous effects. seizures. nightmares. dry mouth (suck sugarless lozenges or ice chips).Drug Generic name: Buspirone hydrochloride Classification Anxiolytic Dosage Adults: Initially. insomnia. tachycardia or palpitation  GI: nausea. abdominal or gastric distress. irritability) of PMS Teaching Points  Take this drug exactly as prescribed.

visual changes. crying. anger. Teaching Points  Take drug exactly as prescribed. polyethylene glycol or benzyl alcohol (parenteral lorazepam). difficulty voiding. 110mg/day in divided doses with largest dose at bedtime. edema of the extremities.  IV: initial dose is 2mg total or 0. salivation  Others: drug dependence with withdrawal syndrome when drug is discontinued.Drug Generic name: Lorazepam Classification Anxiolytic Benzodiazepine Sedativehypnotic Dosage Adults:  Oral: usual dose is 2-6mg/day. GI upset (take drug with food). shock. Contraindication  Contraindicated with hypersensitivity to benzodiazepines.  You may experience these side effects: drowsiness. apathy. Mechanism Of Action Exact mechanisms are not understood.  Report severe dizziness. more common with abrupt discontinuation of higher dosage used for longer than 4 months.05mg/kg up to a maximum of 4mg administered at least 2 hr before operative procedure. fatigue. coma. sedation. disorientation. Indication  Oral: management of anxiety disorder or for short term relief of symptoms of anxiety or anxiety associated with depression.  Parenteral: preanesthetic medication in adults to produce sedation. drowsiness. headache. benzodiazepines potentiate the effects of GABA. rash or skin lesions.  IM: 0. whichever is smaller. insomnia due to anxiety or transient situational stress. acute narrow-angle glaucoma. pregnancy. weakness. range. depression. Brand name: Ativan Pregnancy category: D Controlled substance CIV . Pediatric patients: drug should not be used in children younger than 12 yrs. leaving the cortex relatively unaffected.044 mg/kg. vomiting. avoid driving or engaging in dangerous activities). depression.  Use cautiously with impaired hepatic or renal function. Patient with renal or hepatic impairment: initially. restlessness. an inhibitory neurotransmitter. lightheadedness. acts mainly at subcortical levels of the CNS. dizziness (may be transient. rlieve anxiety. Main site of action may be the limbic system and reticular formation. and decrease racall of events related to surgery. Adjust as needed and tolerated. Adverse Reaction  CNS: transient. confusion. psychoses. emotional upset. paradoxical excitatory reactions during first 2 wk of treatment  EENT: visual and auditory disturbance. diplopia  GI: dry mouth. treatment of status epilepticus. mild drowsiness initially. 12mg/day in divided doses. anxiolytic effects occur at doses well below those needed to cause sedation and ataxia. nocturnal sleep disturbances for several nights after discontinuing the drug if used as a sedative and hypnotic. dreams. do not stop taking drug (in long-term therapy) without consulting health care provider. lactation. nausea. labor and delivery (“floppy infant” syndrome). propylene glycol. lethargy. palpitations. hostility.

DRUG STUDY .

Do’s and Don’ts In the Psyche Ward .