Harvard University Department of Statistics

Stat 140: Design of Experiments

Spring 2007
Instructor:
Professor Rima Izem, Science center office 604, (617) 496-8456, rizem at fas.harvard.edu
T.F:
TBA
Class meetings:
Tue-Thu 1pm-2:30pm, TBA
Additional discussion sections 1hr/week, TBA (check class website for time and location)
Class website:
http://my.harvard.edu/icb/icb.do?keyword=k10325
Textbook (required):
Design and Analysis of Experiments (1999) by A. M. Dean and D.T. Voss. (Springer texts in
statistics).
Other references (not required):
- Design and Analysis of Experiments (6th edition) by Douglas C. Montgomery.
- Statistics for Experimenters: Design, Innovation, and Discovery (2nd Edition) by George E.
P. Box, J. Stuart Hunter, William G. Hunter
- The Theory of the Design of Experiments by D.R. Cox and N. Reid.
Software:
You can use the software of your choice to solve hwk problems or analyze your own data
(for ex: SAS, Matlab, Minitab, Splus, or R). However, only R and Splus will be supported by
the T.F
Prerequisites:
Stat 100 or equivalent, and Math 19a and 19b, or Math 21a and 21b, or equivalent, or above.
Course Requirements and Grading:
- Assigned reading (from textbook) at every class.
- One hwk assignment, solving a set of exercises, every week (usually assigned on
Thursday, due in class the following Thursday). Assignments handed in after the due
time will be subject to a reduction of 20% of the grade for each workday. Lowest
score will be dropped.
- Class (group) project, due during reading session.
- Midterm and final exams are closed books. A calculator is required. You may bring
one sheet of paper with your notes. There will be no make-up exams.
- Final will cover all the material in the class.

Assignments and Exams

Reading
Exercise set
Class project (proposal)
Class project (poster and essay)
Midterm
Final

Occurrence
1 each class
1 set each week
Tue 03-20-07 (in class)
TBA
Thu 03-15-07 (in class)
TBA

% of grade
0
25
0
15
25
35

(Check the class website for the list of assignments (reading and exercise set))
Office hours:
(Instructor): Tue 3pm-4pm and Thu 4pm-5:30pm, Science center 604.
I will also be available in class 5min before and after each class meeting.
(T.F): TBA (check class website for time and location)
Topics to be covered:
Introduction and overview, some basic statistical inference procedures (Chapters 1-2) ANOVA (one factor) (chapters 3-4-5) - Factorial designs (2 factors and more) (chapters 67) - Randomized block design, Latin square, and related designs (chapter 10-11-12) - Random
factors and nested split plot designs (chapters 17-18-19). Special topics: Analysis of
covariance (Chapter 9) - Response surface methodology (Chapter 16) - Fractional factorial
design (Chapter 15).
Class Attendance:
Be on time (classes begin exactly at 1:07pm); bring textbook, and a calculator; turn off your
cell phones, pdas, and laptops during class. An attendance sheet will be passed around during
each class meeting (attendance is not graded).
Collaboration to solve hwk:
I encourage you to work with other students on homework assignments, and use the
discussion link on the class website. However, each student should produce his/her own
work to be graded, and verbatim copying of homework is NOT allowed.
Your comments and suggestions:
Best way to reach me outside the classroom is during my office hours. You may send me an
email, but please allow for 1 business day for a reply. You may also leave me anonymous notes
in my mailbox, or send me an anonymous midterm review through the class website.