1

5
0T

C: NS32

-2008

)( :

) 4(

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hGH

.
.
.
:

+ hGH )
(.
) 6(

6
) .(G6PD 6
. .
:

G6PD . 1
G6PD 2
.

G6PD B
G6PD M
R

186 - 187 -188 - 189 190
...CAC ATC TCC TCC CTG...
...CAC ATC TTC TCC CTG

G6PD B
G6PD M
R

)(%
100
3

)(:

Arg
Ser
Arg
Gly

C
UAU
UAC

UAA
UAG
CAU
CAC
CAA
CAG
AAU
AAC
AAA
AAG
GAU
GAC

GAA
GAG

Tyr

His
Gln
Asn
Lys
Asp
Glu

5
0T

C: NS32

A
UGU
UGC
UGA
UGG
CGU
CGC
CGA
CGG
AGU
AGC
AGA
AGG
GGU
GGC
GGA
GGG

0T

Ser

Pro

Thr

Ala

UCU
UCC
UCA
UCG
CCU
CCC
CCA
CCG
ACU
ACC
ACA
ACG
GCU
GCC
GCA
GCG

U
Phe
Leu
Leu

Ile
Met
Val

UUU
UUC
U UUA
UUG
CUU
CUC
C CUA
CUG
AUU
AUC
A AUA
AUG
GUU
GUC
G GUA
GUG

(1 ) (3
G6PD B G6PD M
1,5) .(
(2
0.5) .(
R

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U
C
A
G
U
C
A
G
U
C
A
G
U
C
A
G

Cys

Trp

) (2008

4
.
(3 3
3 4 7 ) .8 A a
( 2,5) .(
4

G6PD
400 . G6PD 1/20
.
(4 . ) 1(
(5 ) 0.5(
) 3(

. ATP
.

)(:

) (2008

3
0T

5
C: NS32

ATP
:

. pH = 7,5
ATP O 2
R

.1
.

:t1 :t2 :t3 ADP + Pi - :t4 .

2 .

O2

)2(ADP+P
2ATP
2

'R
T
R

Krebs

'R
T

H2O
R'H
TH
RH22
2

ADP+P
R'H
TH22

:T

O2

ATP

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(1 2 ) (ATP O 2
R

1) .O 2(
R

(2 2 1 ATP 2) .(
) 4(

: ...

)(:

) (2008

4
5
C: NS32

. 1 .
T (LT / L) L

200 4000

B (LB / L) L

1000 2000

1250

)(mg/dL

400

(1
) 1(

T4

2
:

(2
2 1
1,5) .3(

(3

.
) 1,5(

www.diwan-svt.com

) T (B

:1

:2

:3

) 3(

.
:

 1 .

)(:

SW

) (2008

5
5
C: NS32

NW

(1 1) .(

.
/ ) (P/T ) ( 2

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) (

. )( .
)(C

)(C

) (

Km

kbar

) (

Km

kbar

(2 2
1) .(

 (3 1 2
1) .(

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