Professional Documents
Culture Documents
KG - Germany
VesicoUreteral Reflux
Treatment Options:
1. Medications: antibiotics such as
cephalosporins, Bactrim,
Amoxicillin.
Treatment Options:
Urethral Injections Bulking Agents:
Is a minimal surgical procedure providing
An alternative in treatment options:
The Ideal Bulking agent of choice must
include following charecteristics:
1. Biocompatible.
2. Biodegradable.
3. Bio-stable: no deformation after
injection.
4. No Migration after implantion.
5. No erosion after implantion.
6. Easy to applicate without the need
to apply pressure when injecting.
Treatment Options:
Available Bulking Agents for VUR:
1. Vantris: polyacrylate polyalcohol
copolymer immersed in 40% glycerol
solution carrier. It is non-resorbable
permanent treatment.
2. Deflux: dextranomere microspheres
50mg/ml in a carrier gel of non-animal
stabilized hyaluronic acid 15mg/ml.
3. CRM Vurdex:
DEAE-Sephadex dextran positively
charged dextranomere.
4. CRM Vurdex composition:
17mg
6.9mg
1.0ml
3. After that and as a long duration effect is favorable in treatment of VUR the
Specially designed cross linking process was applied to DEAE-DEXTRAN to obtain a cross
Linked DEAE-DEXTRANOMERE or what is called a DEAE-Sephadex-Dextran , Sephadex
Is a trade mark for cross linked dextran, where cross linking process results in a long term
Duration of the implant to be degraded gradually.
CRM Vurdex:
CRM Vurdex:
1 syringe 1.0ml
sterile needle
Implantation procedure:
Video is available.
Clinical trials
Clinical trials
Thank You