Solifenacin Manufacturers / Suppliers

Manufacturers pharma intermediates

Somu Organo-Chem Pvt. Ltd is also known for Solifenacin

Manufacturers and Suppliers in Bangalore, Karnataka.
Solifenacin is used as a medicine to treat contraction of
overactive bladder.

SOMU Organo - Chem Pvt. Ltd.

Solifenacin Manufacturers / Suppliers

Somu Organo-Chem Pvt. Ltd is also known for Solifenacin Manufacturers and
Suppliers in Bangalore, Karnataka. Solifenacin is used as a medicine to treat
contraction of overactive bladder.
Somu Organo-Chem Pvt. Ltd was established in the year 1995 with a
manufacturing unit at Malur near Bangalore to manufacture Speciality Fine
Chemicals, Pharma Intermediates, Perfumery and flavour Intermediates, Agro
Chemical Intermediates, Mining Chemicals and Flotation Reagents.

Solifenacin, marketed as solifenacin succinate under the trade name Vesicare, is a

urinary antispasmodic of the anticholinergic class. It is used in the treatment of
overactive bladder with urge incontinence.

Solifenacin is contraindicated for people with urinary retention, gastric retention,

uncontrolled or poorly controlled closed-angle glaucoma, severe liver disease.
Side effects
The most common side effects of solifenacin are dry mouth, blurred vision, and
constipation. As all anticholinergics, solifenacin may rarely cause hyperthermia
due to decreased perspiration.
Solifenacin is metabolized in the liver by the cytochrome P450 enzyme CYP3A4.
When administered concomitantly with drugs that inhibit CYP3A4, such as
ketoconazole, the metabolism of solifenacin is impaired, leading to an increase in
its concentration in the body and a reduction in its excretion.

Mechanism of action
Solifenacin is a competitive cholinergic receptor antagonist, selective for the M 3
receptor subtype. The binding of acetylcholine to these receptors, particularly M 3,
plays a critical role in the contraction of smooth muscle. By preventing the binding
of acetylcholine to these receptors, solifenacin reduces smooth muscle tone in the
bladder, allowing the bladder to retain larger volumes of urine and reducing the
number of micturition, urgency and incontinence episodes. Because of a long
elimination half life, a once-a-day dose can offer 24-hour control of the urinary
bladder smooth muscle tone.
Our Commitment
We Endeavour to be the best company to 'work for' and the best company to 'buy
from'. We will do this through

Surpassing customers expectations by providing prompt, efficient and better

services,
Building and Maintaining Customer Relationships.

Our Mission

To strive relentlessly and constantly improve ourselves, our team, our

products and our services so as to become the best.
To expand our product line and ensure supply of complaint -free products.
To achieve customer satisfaction through continuous improvement.

Somu Organo-Chem Pvt. Ltd

Address:29th Main, 1st Phase, 2nd Stage, BTM Layout,
Bangalore-560 076. KARNATAKA STATE-INDIA.
Phone: +91-80-26783595 / 596 / 26783728 / 26784291
Email: info@somugroup.com
Fax: +91-80-26783729 / 26781255