1. The document reviews 15 literature sources on drug-induced liver injury from anti-tuberculosis drugs.
2. Key topics covered include the incidence, risk factors, patterns of liver enzyme changes, and outcomes of anti-tuberculosis drug-induced hepatotoxicity.
3. Mechanisms of drug-induced liver injury are also discussed, including hepatic metabolism of drugs, current concepts of mechanistic pathways, and challenges in clinical assessment.
1. The document reviews 15 literature sources on drug-induced liver injury from anti-tuberculosis drugs.
2. Key topics covered include the incidence, risk factors, patterns of liver enzyme changes, and outcomes of anti-tuberculosis drug-induced hepatotoxicity.
3. Mechanisms of drug-induced liver injury are also discussed, including hepatic metabolism of drugs, current concepts of mechanistic pathways, and challenges in clinical assessment.
1. The document reviews 15 literature sources on drug-induced liver injury from anti-tuberculosis drugs.
2. Key topics covered include the incidence, risk factors, patterns of liver enzyme changes, and outcomes of anti-tuberculosis drug-induced hepatotoxicity.
3. Mechanisms of drug-induced liver injury are also discussed, including hepatic metabolism of drugs, current concepts of mechanistic pathways, and challenges in clinical assessment.
1. Pedoman Nasional Pengendalian Tuberkulosis. Kementrian Kesehatan
Republik Indonesia. 2014. 2. Chalasani NP, Hayashi PH, Bonkovsky HI, Navarro VJ, Lee WM, et al. ACG Clinical Guidline : The Diagnosis and Management of Idiosyncratic Drug- Induced Liver Injury. Am J Gastroenterol. 2014;131:1-17. 3. Loho IM, Hasan I. Drug-Induced Liver Injury Tantangan dalam Diagnosis. CDK. 2014; 41(3):167-70. 4. Decarbhavi H. Antituberculous Drug Liver Injury: Current Perspective. Tropical Gastroenterology. 2011;32(3):167174 5. Tostmann A, Boeree MJ, Aarnoutse RE, Lange WC, Ven AJ et al. Antituberculosis Drug-Induced Hepatotoxicity: Concise up-to-date Review. J Gastroen Hepatol. 2008;23:192-202. 6. Khalili H, Khavidaki D, Rasoolinejad M, Rezaie L, Etminani M. Anti- tuberculosis drugs related hepatotoxicity; incidence, risk factors, pattern of changes in liver enzymes and outcome. DARU. 2009;17(3):163-7. 7. Ambreen K, Sharma R, Singh KP, Kumar S. Anti-Tuberculosis Drug-Induced Hepatotoxicity: A Review. Int J Adv Biotech Res. 2014:5(3):423-437. 8. Gaude GS. Chaudhury A. Hattiholi J. Drug-induced hepatitis and the risk factors for liver injury in pulmonary tuberculosis patients. J Fam Med. 2015;4(2):238-243. 9. Sukkonen JJ, Cohn DL, Jasmer RM. An Official ATS Statement: Hepatotoxicity of Antituberculosis Therapy. Am J Respir Crit Care Med. 2006;174:935-952. 10. Jeong I, Park JS, Cho YJ, Yoon HI, Song J, Lee CT et al. Drug-induced Hepatotoxicity of Anti-tuberculosis Drugs and Their Serum Levels. J Korean Med Sci. 2015;30:127-172. 11. Bjornsson,E. Review article: drug-induced liver injury in clinical practice. Pharmacol Ther. 2010; 32: 313. 12. Liddle, Christopher and Stedman, Catherine A.M. Hepatic metabolism of drugs. The Textbook of Hepatology: From Basic Science to Clinical Practice, 3rd Edition, July 2007; 2,3,15. 13. Russmann et al. Current Concepts of Mechanisms in Drug-Induced Hepatotoxicity. Curr Med Chem. 2009;16:3041-53. 14. Andrade RJ, Robles M, Fernndez-Castaer A, Lpez-Ortega S, Lpez-Vega MC, Lucena MI. Assessment of drug-induced hepatotoxicity in clinical practice: A challenge for gastroenterologists. World J Gastroenterol.2007; 13(3):329-340. 15. Russmann S.; Jetter A.; Kullak-Ublick G.A.; Pharmacogenetics of Drug- Induced Liver Injury. J Med Hepatol. 2010:5(2):231-40.. 16. Ki Tae Suk, et al. Drug-induced liver injury: present and future. Clinical and Molecular Hepatology 2012;18:249-257.
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