SIKLUS SEL dan APOPTOSIS

Biologi Sel
Binar Asrining Dhiani
 SIKLUS SEL
Terbagi dalam:
Fase G1 (Interphase)
Fase S (Sintesis)
Fase G2
Fase M (Mitosis)
 SIKLUS SEL
State Phase Abbreviation Description
quiescent/ A resting phase where the cell has left the cycle and
Gap 0 G0
senescent has stopped dividing.

Cells increase in size in Gap 1.

Gap 1 G1 The G1 checkpoint control mechanism ensures that
everything is ready for DNA synthesis.

Synthesis S DNA replication occurs during this phase.

Interphase
During the gap between DNA synthesis and mitosis,
the cell will continue to grow.
Gap 2 G2 TheG2 checkpoint control mechanism ensures that
everything is ready to enter the M (mitosis) phase
and divide.
Cell growth stops at this stage and cellular energy is
focused on the orderly division into two daughter
Cell division Mitosis M cells. A checkpoint in the middle of mitosis
(Metaphase Checkpoint) ensures that the cell is ready
to complete cell division.
Video Siklus Sel
APOPTOSIS
 APOPTOSIS
The process of programmed cell death (PCD) that may occur
in multicellular organisms.
Biochemical events lead to characteristic cell changes (morphology)
and death. These changes include blubbing , cell shrinkage,
nuclear fragmentation, chromatin condensation,
and chromosomal DNA fragmentation.
Produces cell fragments called apoptotic bodies that phagocytic
cells are able to engulf and quickly remove before the contents of
the cell can spill out onto surrounding cells and cause damage.
In contrast to necrosis, which is a form of traumatic cell death that
results from acute cellular injury, apoptosis, in general, confers
advantages during an organism's life cycle.
For example, the differentiation of fingers and toes in a developing
human embryo occurs because cells between the fingers apoptose;
the result is that the digits are separate.
Between 50 and 70 billion cells die each day due to apoptosis in
the average human adult. For an average child between the ages of
8 and 14, approximately 20 billion to 30 billion cells die a day.