Professional Documents
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University of Hull – Healthcare News 2010
News of events and research developments can be found in Healthcare News ◙
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HEFCE welcomes revised timetable for REF
David Willetts, Minister of State for Universities and Science has confirmed a revised timetable for the REF.
See the HEFCE ◙ website for details.
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NHS White Paper – Equity and Excellence: Liberating the NHS ◙
The Government has published a White Paper, "Equity and excellence: Liberating the NHS". It makes
extensive reference to the importance of the conduct of research, and the use of research evidence, as key
elements of the NHS. "The Government is committed to the promotion and conduct of research as a core
NHS role". (para 3.16)
"Research is even more important when resources are under pressure - it identifies new ways of preventing,
diagnosing and treating disease. It is essential if we are to increase the quality and productivity of the NHS,
and to support growth in the economy." (para 3.16)
The White Paper demonstrates an understanding that much of the bureaucracy relating to medical research
is a result of legislation. "The Government will cut the bureaucracy involved in medical research. We have
asked the Academy of Medical Sciences to conduct an independent review of the regulation and governance
of medical research. In the light of this review we will consider the legislation affecting medical research, and
the bureaucracy that flows from it, and bring forward plans for radical simplification". (para 5.8)
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The House of Lords Science and Technology Committee
The Committee has launched a new inquiry into the effectiveness of behaviour change interventions in
achieving government policy goals and helping to meet societal challenges, such as reducing carbon emissions
and alleviating the burden on health services caused by smoking, drinking and the rise in obesity. As part of
its inquiry, the Committee will conduct two case studies. The first will look at behaviour change
interventions designed to reduce obesity, which remains a significant challenge for society as prevalence
rates continue to rise. The subject matter of the second will be decided later in the year.
The Committee have published a call for evidence in which they welcome evidence covering a range of
areas, both generally in regard to behaviour change interventions or specifically about those interventions
aimed at tackling obesity. For more information and the full Call for Evidence please see the Committee
website ◙
Recent Local Publications:
Bradley S, Carradice D. Research and training ◙ BMJ Careers, 28 April 2010. DOI:
10.1136/bmj.c2139
Cleland J G, Coletta A P, Buga L, Ahmed D, Clark A L. Clinical trials update from the American
College of Cardiology meeting 2010: DOSE, ASPIRE, CONNECT, STICH, STOP-AF,
CABANA, RACE II, EVEREST II, ACCORD, and NAVIGATOR ◙ European Journal of Heart
Failure, 2010;12(6):623-9.
Cleland J G, Tageldien A, Buga L, Wong K, Gorcsan J 3rd. Should we be trying to define responders
to cardiac resynchronization therapy? JACC Cardiovascular Imaging, 2010; 3(5): 541-9. DOI
10.1016/j.jcmg.2010.04.003
Cleland J G, Yassin A S, Khadjooi K. Acute heart failure: focusing on acute cardiogenic pulmonary
oedema ◙ Clinical Medicine, 2010, 10 (1): 59-64.
Elston J, Ling M, Jeffs B, Adams K, Thaker H, Moss P, Meigh R, Barlow G. An evaluation of the
usefulness of Staphylococcus aureus serodiagnosis in clinical practice ◙ European Journal of
Clinical Microbiology and Infectious Disease, 2010, 29(6):737-9. DOI 10.1007/s10096-010-0907-1
Shelton R L, Ingle L, Rigby A S, Witte K K, Cleland J G, Clark A L. Cardiac output does not limit
submaximal exercise capacity in patients with chronic heart failure ◙ European Journal of Heart
Failure, 4 June 2010, Epub ahead of print. DOI: 10.1093/eurjhf/hfq086
Events:
World Cancer Research Fund: Nutrition, Physical Activity and Cancer Prevention:
Current Challenges, New Horizons
Sunday 12 and Monday 13 September 2010, Royal College of Physicians, London
This conference will provide a forum for the dissemination of results in the nutrition, physical activity
and cancer field and will examine how this knowledge can be used by policy-makers to inform and
generate thinking and ways of preventing cancer. For further information please see the Fund’s
website ◙
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Leading and Delivering Research and Innovation in the NHS
Monday 27 – Wednesday 29 September 2010, Radcliffe Conference and Training
Centre, The University of Warwick, Coventry
This course has been developed in response to national policy initiatives which will require every
NHS organisation to review their strategies around research and innovation. As spending is reined
in, the NHS must find ways to increase quality without raising costs. For full details and how to
register, please see Research & Innovation Limited’s website ◙
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Creating Innovative NHS Organisation
Tuesday 12 October 2010, Radcliffe Conference and Training Centre, The
University of Warwick, Coventry
This course has been developed in support of the NHS policy requirements around improving
quality and productivity. The purpose is to provide staff with responsibility for innovation with the
knowledge and skills required to support their organization in 'unlocking' innovation to enhance
quality, productivity and patient care. For full details and how to register please see R & D
Forum’s website ◙
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Improving Access to Clinical Research in the NHS
Tuesday 12 October 2010, City Inn, Birmingham
This event will provide examples of best practice, novel ideas and expert advice designed to help R &
D professionals attract new partners, support cultural change and deliver faster approval times. For
more information see SBK Healthcare’s website ◙
For Information:
A Standard Approach to Biobanking
Anne Carter, Portfolio Lead for onCore UK gives her thoughts on the new CCB initiative to develop best
practice guidelines and a way to benchmark biobanks – see onCore’s website ◙
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American Association for Cancer Researchers 101st Annual Meeting
Congressionally Directed Medical Research Programs have posted videos of presentations made at this
meeting giving an overview of their organisation and how to apply for grants. These can be viewed on their
website ◙
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General Medical Council – Research Guidance
Supplementary guidance Good Practice in Research and Consent to Research set out the good practice principles
that doctors are expected to understand and follow if they are involved in research. Online versions are
available on the GMC’s website ◙
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Joseph Rowntree Foundation
The Foundation is developing a new programme focusing on poverty and ethnicity, to be launched in 2011.
As part of an extensive scoping process for the programme, six expert distillation papers are being
commissioned to discuss various aspects of the relationship between poverty and ethnicity. The papers will
help to generate and shape ideas for the new programme. For information please see the Foundation’s
website ◙
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MHRA Drug Safety Update
This is a monthly electronic bulletin from the MHRA and Commission on Medicines bringing the latest
information and advice on the safer use of medicines. Please see the MHRA website ◙ for updates and to
sign up for email notifications of new issues.
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National Institute for Health Research
RDInfo have compiled a useful Jargon Buster ◙
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NRES Guidance on Data Monitoring Committees
This guidance describes responsibilities for oversight of safety issues in clinical trials, the circumstances in
which an independent data monitoring committee (DMC) may be required and the role played by the DMC.
The guidance can be found on the NRES website ◙
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NCRI Cancer Biosample Directory goes live
A directory has been launched which is intended to be a signpost for researchers to find human biosamples
for use in their research. Inclusion in the directory provides tissue collection custodians with the chance to
make researchers aware of their resources, invite requests for access to samples and provide opportunities
for collaborations. A Cancer Clinical Trials Biosample Directory is also available as a separate listing. Please
see the NCRI website ◙ for further information.
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North and East Yorkshire R&D Alliance Unit
Revised Standard Operating Procedure s:
Five revised Templates have been published for internal R&D use and are not published on the
website:
R&D/CTIMP/T21: Feasibility Review Result Letter (version 1.0)
R&D/CTIMP/T22: Sponsorship in Principle Letter (version 1.0)
R&D/CTIMP/T23: Final Sponsorship Letter (version 1.0)
R&D/CTIMP/T06: Amendment Acknowledgement Letter (2.0)
R&D/T02: Amendment Acknowledgement Letter (version 2.0)
Funding Opportunities:
Parkinson’s Disease Society – PhD Studentships ◙
These are fully funded studentships for outstanding students.
Deadline for applications: Friday 27 August 2010
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European Chemical Industry Council – Various Awards ◙
Toxicogenomics as Mechanistic Readouts from In Vitro Studies
Capacity of the Endocrine System to cope with combined exposure to exogenous
endocrine active substances at environmentally relevant concentrations
Threshold of toxicological concern for inhalation exposure
Closing date for all: Tuesday 31 August 2010
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3R Research Foundation – Project Grants ◙
These are for research aimed at reducing the use of animals in scientific experiments.
Closing date: Wednesday 1 September 2010
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Action Medical Research – Research Training Fellowship ◙
These Fellowships are for training in research techniques and methodology in a subject relevant to
the overall aims of the Charity – saving and changing children‟s lives.
Closing date: Wednesday 1 September 2010
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Breast Cancer Campaign – Pilot Grants ◙
These are for established scientists to investigate and develop new ideas in the field of breast cancer
research.
Closing date: Friday 3 September 2010
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Epilepsy Research Foundation – Commercialisation Grants ◙
This project is offering 1:1 matching grants of up to $100,000 to academic and commercial entities
to support the commercialization of novel approaches to the treatment of epilepsy.
Deadline for submission of Letters of Intent: Friday 3 September 2010
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National Institute of General Medical Sciences – Structural Biology of Membrane
Proteins – AIDS Related ◙
This programme solicits AIDS related applications to develop research and methods to enhance the
rate of membrane protein structure determination and to determine specific membrane protein
structures.
Closing date: Tuesday 7 September 2010
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Technology Strategy Board – Living Well With Dementia ◙
This competition is for new innovations to enable people with dementia to live more independently.
Closing date: Thursday 9 September 2010
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National Institute for Health Research
Unplanned Hospital Admissions ◙
Proposals are invited for primary research which examines the organisational behaviours, systems
and relationships across boundaries required to prevent and reduce unplanned hospital admissions.
Responsive Funding in the NIHR SDO Programme ◙
The focus of this programme is to fund secondary research studies. Constraints are not placed on
the nature, source or type of the existing data that research projects might seek to use – they could
be qualitative and/or quantitative; held in electronic, paper or other forms; produced by NHS
organisations or by other national bodies or professional bodies/groups; and in the public domain or
privately held.
Expedited Evidence Synthesis to Support Decision-making by Managers and Leaders in
the NHS ◙
This call is specifically for evidence syntheses and has three main purposes: to respond to the
research needs of NHS decision-makers by commissioning rapid evidence syntheses; to produce
short research reports based on those evidence syntheses which will be easily accessible to research
users in the NHS management with findings which are relevant; and to identify gaps in research
knowledge of importance to the NHS management community to enable the programme to better
target future research commissioning.
Deadline for all: 1pm, Thursday 16 September 2010
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National Institute of Mental Health – Epigenomic Modifications in Neurodevelopment
◙
This funding is for research that proposes to characterize pivotal epigenetic events in
neurodevelopmental processes or uses preclinical and/or translational models to examine
epigenomic profiles related to early environmental influences and vulnerability to mental
disorders. Studies that provide cross-species analysis and/or studies that address heterogeneity
of epigenetic marks across tissue types, are of particular interest.
Deadline for receipt of Letters of Intent: 20 September 2010
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American Society of Clinical Oncology
Young Investigator Award ◙
This Award is to fund physicians during the transition from a fellowship programme to a faculty
appointment.
Career Development Award ◙
This Award provides funding to clinical investigators in their first faculty appointment to establish an
independent clinical cancer research programme.
Closing date: Tuesday 21 September 2010
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Jérôme Lejeune Foundation – Research Grants ◙
These are for projects leading to treatments that will improve the abilities of patients suffering from
genetic diseases with mental deficiency, especially Trisomy 21
Closing date: Thursday 23 September 2010
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National Institute for Health Research – The Research for Patient Benefit Programme
◙
This programme invites applications for applied research projects to provide benefit for NHS
patients and other users of health and social care services. RfPB is a nationally co-ordinated funding
stream for regionally commissioned research.
Closing date: Friday 24 September 2010
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Wellcome Trust – Research Training Fellowships ◙
This scheme is for medical, dental, or clinical psychology graduates who have little or no research
training, but who wish to develop a long-term career in academic medicine. Applications are
encouraged from individuals who wish to undertake substantial training through high-quality research
towards a PhD or MD qualification.
Deadline for applications: Friday 24 September 2010
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Bayer Schering Pharma AG – Research Grants ◙
These support collaborative research projects on novel molecular targets in oncology, cardiology,
gynecology and in vivo imaging.
Closing date: Thursday 30 September 2010
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Biotechnology and Biological Sciences Research Council – Research Fellowships ◙
Various awards are available for researchers at different stages of their careers.
Closing date: Thursday 30 September 2010
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International Council on Amino Acid Science – Research Grants ◙
The aim of these grants is to enhance knowledge on upper limits of amino acid intakes by humans.
Closing date: Thursday 30 September 2010
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Nutricia Research Foundation – Research Grants ◙
These provide funding for nutrition related research for up to two years.
Closing date: Thursday 30 September 2010
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Canada Gairdner Foundation International Awards
Global Health Award ◙
This Award is directed at health issues pertaining to developing countries. It recognises those who
have made major scientific advances which have, or have potential to make a significant impact on
health outcomes in the developing world.
International Award ◙
The aim of this Award is to honour and reward outstanding biomedical scientists who have made
original contributions to medicine with the ultimate goal of contributing through research to the
conquest of disease and relief of human suffering. The Foundation invites the scientific community to
nominate qualified scientists from every branch of biomedicine.
Nomination deadline for both awards: Friday 1 October 2010
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Cancer Research Institute - Irvington Institute Fellowship Programme ◙
These fellowships are designed to foster the training of qualified young scientists in cancer
immunology or general immunology.
Deadline for applications: Friday 1 October 2010
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Epilepsy Foundation – Research and Training Fellowships for Clinicians ◙
These Fellowships are for clinically trained professionals for one year of supervised study and
research.
Closing date: Friday 1 October 2010
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European Crohn’s and Colitis Organisation – IBD Research Grants and Fellowships ◙
These awards are intended to promote innovative scientific research in the area of IBD.
Closing date: Friday 1 October 2010
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European Respiratory Society – Visiting Professorship ◙
These are to enable senior investigators and clinicians to conduct exchange visits.
Closing date: Friday 1 October 2010
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European Society for Paediatric Research – Young Investigators Fellowships ◙
These promote and support basic and clinical research into the causes, prevention and treatment of
disease in children. The programme encourages young investigators to undertaken their research in
a foreign research institution.
Closing date: Friday 1 October 2010
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Federation of European Microbiological Societies – Advanced Fellowship ◙
These are for promising microbiologists who have less than 3 years of postdoctoral experience.
Closing date: Friday 1 October 2010
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Pathological Society of Great Britain and Ireland – Small Grants Scheme ◙
This Scheme aims encourage trainees, Specialist Registrars (or Honorary Specialist Registrars), in
Histopathology or Immunology to undertake investigative research, and is particularly aimed at
generating research data which may contribute towards a substantive application to a research
funding body.
Closing date: Friday 1 October 2010
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Roche Organ Transplantation Research Foundation – Project Grants ◙
Priority is given to clinically oriented research projects that use human transplant samples for
laboratory examinations.
Closing date: Friday 1 October 2010
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International Diabetes Federation – BRiDGES Project ◙
Relevant topics for this project include: methods to improve health care delivery for patients with or
at risk of diabetes; strategies to enhance diabetes self management; methods to develop strategies to
promote healthy lifestyles to reduce the risk of diabetes; new cost effective ways to identify people
with pre-diabetes and treat diabetes.
Closing date: Friday 1 October 2010
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Wellcome Trust – Health Innovation Challenge Fund ◙
Wellcome and The Department of Health are collaborating to stimulate the creation of innovative
healthcare products, technologies and interventions, and facilitate their development for the benefit
of patients in the NHS and beyond.
Deadline for preliminary applications: Friday 1 October 2010
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National Institute on Aging – Subjective Well-Being: Advances in Measurement and
Applications to Aging ◙
This funding is for projects that propose to advance the application of well-being measurement to
the integrated study of experienced and evaluative well-being in aging-relevant contexts.
Deadline for receipt of Letters of Intent: 3 October 2010
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National Institute of Allergy and Infectious Diseases – Partnerships for Next
Generation Biodefense Diagnostics ◙
Applications are invited for research focused on early stage product development projects to
establish proof-of-concept for novel or emerging, rapid and innovative clinical diagnostic
technologies, that do not involve nucleic acid amplification methods to detect NIAID Category A,
B, or C Priority Pathogens and toxins.
Closing date for letters of intent: Monday 4 October 2010
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The Health Foundation – The Shine Challenge 2011 ◙
The Challenge is to find new approaches to delivering healthcare that reduce the need for acute
hospital care – while improving quality and saving money.
Closing date: Monday 4 October 2010
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National Center for Complementary and Alternative Medicine – Biology of Manual
Therapies ◙
The research objective of this funding opportunity is to encourage the submission of high quality
studies of the basic science and mechanisms of action underlying the biomechanical, immunological,
endocrinological or neurophysiological consequences of manual therapies.
Closing date: Tuesday 5 October 2010
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National Institute on Aging – Alzheimer’s Disease Drug Development Program ◙
The objective of this program is to stimulate research in the pre-clinical development and testing
of novel therapeutic compounds aimed at slowing, halting, or reversing the progressive decline in
cognitive function and modifying the behavioral symptoms in Alzheimer's disease; or delaying the
onset of or preventing AD, mild cognitive impairment, or age-related cognitive decline.
Closing date: Tuesday 5 October 2010
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National Institute of Diabetes and Digestive and Kidney Diseases, US – Development
of Assays for High Throughput Drug Screening ◙
The goal of this programme is to establish a stream of scientifically and technologically outstanding
assays that can be automated for HTS.
Closing date: Tuesday 5 October 2010
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National Institute of General Medical Sciences – Structural Biology of Membrane
Proteins ◙
This programme solicits applications to develop research and methods to enhance the rate of
membrane protein structure determination and to determine specific membrane protein structures.
Closing date: Tuesday 5 October 2010
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National Institute for Occupational Safety and Health – Occupational Safety and
Health Research ◙
This funding is to develop an understanding of the risks and conditions that are associated with
occupational diseases and injuries, to explore methods for reducing risks and for preventing or
minimizing exposure to hazardous conditions in the workplace, and to translate significant
scientific findings into prevention practices and products that will effectively reduce work -related
illnesses and injuries.
Closing date: Tuesday 5 October 2010
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National Institute on Alcohol Abuse and Alcoholism – Expanding and Personalizing
Treatment Options for Alcohol Use Disorders ◙
This funding is for projects that study how genetic variation affects responses to medications for
the treatment of Alcohol Use Disorders.
Closing date: Tuesday 5 October 2010
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National Institutes of Health – The Central Processing of Taste Information ◙
The purpose of these grants is to foster basic and clinical research on the central mechanisms
underlying the perception of taste quality.
Closing date: Tuesday 5 October 2010
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Biotechnology and Biological Sciences Research Council
New Investigator Scheme ◙
This scheme assists early-career researchers to secure their first major element of research funding.
Responsive Research Grants ◙
Grants are awarded in response to unsolicited research proposals in any area relevant to BBSRC‟s
mission. A variety of investigator-led research activities can be applied for.
Closing date for both: Wednesday 6 October 2010
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Medical Research Council
Neurosciences and Mental Health Research Grants ◙
MRC research grants are suitable for focused research projects that may be short- or long-term in
nature. In addition, they can be used to support method development or development and
continuation of research facilities and may involve more than one research group or institution.
New Investigator Grants – Neurosciences and Mental Health ◙
These grants are aimed at researchers who are capable of becoming principal investigators and who
are now ready to take the next step towards that goal.
Closing date for both: Wednesday 6 October 2010
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National Institute on Aging – Cell Lineage Determination and Tissue Homeostatis in
the Aged ◙
Applications are sought from organizations that propose to track cell lineages and to determine cell
life spans in normal tissue homeostasis and in response to injury or disease in the elderly.
Closing date: Thursday 7 October 2010
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NIHR Health Technology Assessment Programme – HTA Clinical Evaluation and
Trials ◙
This programme supports research that is immediately useful to clinical practice and policy/decision
makers. HTA research is undertaken when there is evidence to show the technology is efficacious
but there is uncertainty around its clinical and cost effectiveness in a real life NHS setting in
comparison to the current best alternative(s).
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Epilepsy Action
PhD Studentship ◙
Research Project Grants ◙
Proposals are invited for non-laboratory based research projects into the causes and cures for
epilepsy.
Closing date for both: Friday 8 October 2010
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Medical Research Council
Population Health Scientist Fellowship ◙
This scheme is open to early career researchers seeking to acquire multidisciplinary research
training in a range of disciplines.
Career Development Award in Biostatics ◙
This scheme is available to individuals with PhDs in statistics, biostatistics or a related discipline and
less than five years post-doctoral experience or to those who expect to have received such a
doctorate by the time they intend to take up the award.
Methodology Research Fellowship ◙
The MRC methodology research fellowship is a post-doctoral award aimed at providing a period of
specialist training in health research methodology. The scheme is aimed at researchers with a
grounding in health research. ,
Closing date for all: Friday 8 October 2010
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National Institute for Health Research – Programme Grants for Applied Research ◙
These grants support applications in all areas of applied health research.
Deadline for stage 1 applications: Monday 11 October 2010
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Wellcome Trust – Society Awards ◙
These Awards are for ambitious and creative projects that engage people with developments in
biomedical science on a regional or national scale. The theme for this year‟s awards is Grey Matters:
Brain, Mind & Culture.
Closing date: Tuesday 12 October 2010
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Arthritis Research UK
Project Grants ◙
Arthritis Research UK will consider support of clinical projects relating to pathogenesis, diagnosis or
treatment, as well as projects of a more fundamental scientific nature, provided that they offer
promise of advancement in the understanding of arthritis and related musculoskeletal diseases.
Equipment Grants ◙
Applications will be considered only from established units with a track record of research in
arthritis and related musculoskeletal diseases, and the equipment must be able to make a lasting
impact on this research over a period of many years.
Closing date for both: Wednesday 13 October 2010
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Medical Research Council
Methodology Research Fellowship ◙
This includes research on methods development to underpin the biomedical sciences, experimental
medicine, clinical trials, population health sciences, health services research and health policy.
Methodology Underpinning Patient Reported Outcome Measures ◙
The MRC wishes to develop a portfolio of research aimed at improving the methodology
underpinning the application and evaluation of PROMs in health research and health care decision
making.
US Department of Health ◙
Opportunities are frequently available –check their website on a regular basis or sign up to their quarterly
newsletter by clicking the link on there.
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