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INOTROPES/VASOPRESSORS CHEAT SHEET

Overview

Definitions
A. Inotropes medications that increase the hearts force of contraction
B. Vasopressors medications that increase blood pressure by constricting arteries
C. Vasoactive agents a term used to describe medications that alter vascular tone
(vasodilate, vasoconstrict)

Indications
A. Increase mean arterial pressure (MAP)
1. Brain needs MAP of 65-70 mm Hg
2. Kidneys need MAP of 60 mm Hg
B. Improve cardiac output
1. Increasing force of contraction (inotropy)
2. Increasing rate of contraction (chronotropy)
C. Perfuse shunted tissues
1. Increase blood flow to compromised tissue
2. Compensate for loss of function due to inadequate circulation

Presiding Principles

Vasopressors are toxic to tissues and should be used only when absolutely necessary.

Most vasopressors are vesicants that should be administered through a well-established


central venous access. Peripheral sites or short central lines (e.g. cordis introducers,
angiocaths in the femoral vessel) may be used as a short-term solution but should be replaced
as soon as possible.

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