Datasheet of PD0332991 Isethionate

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Product Name PD0332991 Isethionate

6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-
Chemical Name
yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one 2-hydroxyethane-1-sulfonate

Synonyms PD 332991; Palbociclib Isethionate

CAS No. 827022-33-3 Catalog No 52012

Molecular Weight 573.66 OH

O
H
S O N N N

Molecular Formula C24H29N7O2.C2H6O4S HO

O

N N
N

Other information N/A O NH

Items Specifications Results

Appearance Off-white solid Complies

HNMR 400MHz,d6-DMSO Complies

Analysis
HPLC 98.0% Complies

Storage condition Kept under dry and cool condition

The above substance has been tested according to In house Standards, and it
Conclusion
meets requirements.

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 Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11
Description nM/16 nM. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase
3.

No.8 Rd, The Great Wall Park, Donghu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com